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Gene Ontology Browser
Term Detail
GO term:focal adhesion assembly
Synonym: focal adhesion formation
GO id:GO:0048041
Definition:The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological adhesion
                        is-acell adhesion
                                is-acell-substrate adhesion
                                        is-acell-matrix adhesion
                                                is-acalcium-dependent cell-matrix adhesion
                                                is-acalcium-independent cell-matrix adhesion
                                                is-acell-matrix adhesion involved in ameboidal cell migration +
                                                part-offocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                        regulatesregulation of focal adhesion assembly +
                                                is-amesangial cell-matrix adhesion
                                                negatively-regulatesnegative regulation of cell-matrix adhesion +
                                                positively-regulatespositive regulation of cell-matrix adhesion +
                                                regulatesregulation of cell-matrix adhesion +
                                                is-asmooth muscle cell-matrix adhesion +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component biogenesis
                                part-ofcellular component assembly
                                        is-acell junction assembly
                                                is-aadherens junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component biogenesis
                                part-ofcellular component assembly
                                        is-acell junction assembly
                                                is-acell-substrate junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-aadherens junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-acell-substrate junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-acell junction organization
                                        is-acell-cell junction organization
                                                is-aadherens junction organization
                                                        is-aadherens junction assembly
                                                                is-acell-substrate adherens junction assembly
                                                                        is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                                negatively-regulatesnegative regulation of focal adhesion assembly
                                                                                positively-regulatespositive regulation of focal adhesion assembly
                                                                                regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-acellular component assembly
                                        is-acell junction assembly
                                                is-aadherens junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-acellular component assembly
                                        is-acell junction assembly
                                                is-acell-substrate junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell adhesion
                                        is-acell-substrate adhesion
                                                is-acell-matrix adhesion
                                                        is-acalcium-dependent cell-matrix adhesion
                                                        is-acalcium-independent cell-matrix adhesion
                                                        is-acell-matrix adhesion involved in ameboidal cell migration +
                                                        part-offocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                negatively-regulatesnegative regulation of focal adhesion assembly
                                                                positively-regulatespositive regulation of focal adhesion assembly
                                                                regulatesregulation of focal adhesion assembly +
                                                        is-amesangial cell-matrix adhesion
                                                        negatively-regulatesnegative regulation of cell-matrix adhesion +
                                                        positively-regulatespositive regulation of cell-matrix adhesion +
                                                        regulatesregulation of cell-matrix adhesion +
                                                        is-asmooth muscle cell-matrix adhesion +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-aadherens junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-acell-substrate junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell-cell junction organization
                                                is-aadherens junction organization
                                                        is-aadherens junction assembly
                                                                is-acell-substrate adherens junction assembly
                                                                        is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                                negatively-regulatesnegative regulation of focal adhesion assembly
                                                                                positively-regulatespositive regulation of focal adhesion assembly
                                                                                regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell adhesion
                                        is-acell-substrate adhesion
                                                is-acell-matrix adhesion
                                                        is-acalcium-dependent cell-matrix adhesion
                                                        is-acalcium-independent cell-matrix adhesion
                                                        is-acell-matrix adhesion involved in ameboidal cell migration +
                                                        part-offocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                negatively-regulatesnegative regulation of focal adhesion assembly
                                                                positively-regulatespositive regulation of focal adhesion assembly
                                                                regulatesregulation of focal adhesion assembly +
                                                        is-amesangial cell-matrix adhesion
                                                        negatively-regulatesnegative regulation of cell-matrix adhesion +
                                                        positively-regulatespositive regulation of cell-matrix adhesion +
                                                        regulatesregulation of cell-matrix adhesion +
                                                        is-asmooth muscle cell-matrix adhesion +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-aadherens junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell junction assembly
                                                is-acell-substrate junction assembly
                                                        is-acell-substrate adherens junction assembly
                                                                is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                        negatively-regulatesnegative regulation of focal adhesion assembly
                                                                        positively-regulatespositive regulation of focal adhesion assembly
                                                                        regulatesregulation of focal adhesion assembly +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell junction organization
                                        is-acell-cell junction organization
                                                is-aadherens junction organization
                                                        is-aadherens junction assembly
                                                                is-acell-substrate adherens junction assembly
                                                                        is-afocal adhesion assembly [GO:0048041] (44 genes, 49 annotations)
                                                                                negatively-regulatesnegative regulation of focal adhesion assembly
                                                                                positively-regulatespositive regulation of focal adhesion assembly
                                                                                regulatesregulation of focal adhesion assembly +


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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory