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Gene Ontology Browser
Term Detail
GO term:phagocytosis
GO id:GO:0006909
Definition:An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-a2-aminoethylphosphonate transport
                                        is-aacetate ester transport +
                                        is-aalkane transport
                                        is-aamide transport +
                                        is-aamine transport +
                                        is-acarbohydrate derivative transport +
                                        is-acarbohydrate transport +
                                        is-acargo loading into vesicle +
                                        is-achaperone-mediated protein transport +
                                        is-acofactor transport +
                                        is-acutin transport
                                        is-aDNA import into cell involved in transformation
                                        is-adrug transport +
                                        is-adsRNA transport
                                        is-aeye pigment precursor transport
                                        is-afatty acid derivative transport +
                                        is-afatty-acyl group transport
                                        is-afluid transport +
                                        is-agas transport +
                                        is-aglycoside transport +
                                        is-ahormone transport +
                                        is-ahydrogen transport +
                                        is-aion transport +
                                        is-airon coordination entity transport +
                                        is-alactone transport
                                        is-alipid hydroperoxide transport
                                        is-alipid transport +
                                        is-alipoprotein transport
                                        is-amonoamine transport +
                                        is-amultivesicular body sorting pathway
                                        is-aneurotransmitter transport +
                                        is-anitric oxide transport
                                        is-anucleobase transport +
                                        is-aone-carbon compound transport +
                                        is-aorganic acid transport +
                                        is-aorganic hydroxy compound transport +
                                        is-aorganic phosphonate transport +
                                        is-aorganophosphate ester transport +
                                        is-aovarian nurse cell to oocyte transport +
                                        is-aphagocytosis [GO:0006909] (114 genes, 183 annotations)
                                                is-aapoptotic cell clearance +
                                                part-ofFc-gamma receptor signaling pathway involved in phagocytosis
                                                part-ofimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                                negatively-regulatesnegative regulation of phagocytosis +
                                                part-ofopsonization +
                                                part-ofphagocytosis, engulfment +
                                                part-ofphagocytosis, recognition +
                                                part-ofphagolysosome assembly +
                                                positively-regulatespositive regulation of phagocytosis +
                                                regulatesregulation of phagocytosis +
                                        is-apigment granule transport +
                                        is-apolyamine transport +
                                        is-aprotein import +
                                        is-aprotein transport across periplasmic space +
                                        is-aprotein transport within extracellular region
                                        is-aquaternary ammonium group transport +
                                        is-areceptor internalization +
                                        is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                        is-arRNA transport +
                                        is-asecretion +
                                        is-asilicate transport +
                                        is-asingle-organism intercellular transport +
                                        is-asingle-organism intracellular transport +
                                        is-asingle-organism pinocytosis +
                                        is-asnRNA transport +
                                        is-asperm entry
                                        is-asulfur compound transport +
                                        is-asynaptic vesicle transport +
                                        is-athioester transport +
                                        is-atranscytosis +
                                        is-atransepithelial transport +
                                        is-atransmembrane transport +
                                        is-atRNA transport +
                                        is-aubiquitin-dependent endocytosis +
                                        is-avascular transport +
                                        is-avesicle transport along actin filament
                                        is-avesicle-mediated transport involved in floral organ abscission +
                                        is-avitamin transport +
                                        is-axenobiotic transport +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-avesicle-mediated transport
                                        is-aendocytosis
                                                is-aendocytosis involved in viral entry into host cell +
                                                negatively-regulatesnegative regulation of endocytosis +
                                                is-aphagocytosis [GO:0006909] (114 genes, 183 annotations)
                                                        is-aapoptotic cell clearance +
                                                        part-ofFc-gamma receptor signaling pathway involved in phagocytosis
                                                        part-ofimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                                        negatively-regulatesnegative regulation of phagocytosis +
                                                        part-ofopsonization +
                                                        part-ofphagocytosis, engulfment +
                                                        part-ofphagocytosis, recognition +
                                                        part-ofphagolysosome assembly +
                                                        positively-regulatespositive regulation of phagocytosis +
                                                        regulatesregulation of phagocytosis +
                                                is-apinocytosis +
                                                positively-regulatespositive regulation of endocytosis +
                                                is-areceptor-mediated endocytosis +
                                                regulatesregulation of endocytosis +
                                                is-asperm entry
                                                is-asynaptic vesicle endocytosis +
                                                is-aubiquitin-dependent endocytosis +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-a2-aminoethylphosphonate transport
                                                is-aacetate ester transport +
                                                is-aalkane transport
                                                is-aamide transport +
                                                is-aamine transport +
                                                is-acarbohydrate derivative transport +
                                                is-acarbohydrate transport +
                                                is-acargo loading into vesicle +
                                                is-achaperone-mediated protein transport +
                                                is-acofactor transport +
                                                is-acutin transport
                                                is-aDNA import into cell involved in transformation
                                                is-adrug transport +
                                                is-adsRNA transport
                                                is-aeye pigment precursor transport
                                                is-afatty acid derivative transport +
                                                is-afatty-acyl group transport
                                                is-afluid transport +
                                                is-agas transport +
                                                is-aglycoside transport +
                                                is-ahormone transport +
                                                is-ahydrogen transport +
                                                is-aion transport +
                                                is-airon coordination entity transport +
                                                is-alactone transport
                                                is-alipid hydroperoxide transport
                                                is-alipid transport +
                                                is-alipoprotein transport
                                                is-amonoamine transport +
                                                is-amultivesicular body sorting pathway
                                                is-aneurotransmitter transport +
                                                is-anitric oxide transport
                                                is-anucleobase transport +
                                                is-aone-carbon compound transport +
                                                is-aorganic acid transport +
                                                is-aorganic hydroxy compound transport +
                                                is-aorganic phosphonate transport +
                                                is-aorganophosphate ester transport +
                                                is-aovarian nurse cell to oocyte transport +
                                                is-aphagocytosis [GO:0006909] (114 genes, 183 annotations)
                                                        is-aapoptotic cell clearance +
                                                        part-ofFc-gamma receptor signaling pathway involved in phagocytosis
                                                        part-ofimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                                        negatively-regulatesnegative regulation of phagocytosis +
                                                        part-ofopsonization +
                                                        part-ofphagocytosis, engulfment +
                                                        part-ofphagocytosis, recognition +
                                                        part-ofphagolysosome assembly +
                                                        positively-regulatespositive regulation of phagocytosis +
                                                        regulatesregulation of phagocytosis +
                                                is-apigment granule transport +
                                                is-apolyamine transport +
                                                is-aprotein import +
                                                is-aprotein transport across periplasmic space +
                                                is-aprotein transport within extracellular region
                                                is-aquaternary ammonium group transport +
                                                is-areceptor internalization +
                                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                                is-arRNA transport +
                                                is-asecretion +
                                                is-asilicate transport +
                                                is-asingle-organism intercellular transport +
                                                is-asingle-organism intracellular transport +
                                                is-asingle-organism pinocytosis +
                                                is-asnRNA transport +
                                                is-asperm entry
                                                is-asulfur compound transport +
                                                is-asynaptic vesicle transport +
                                                is-athioester transport +
                                                is-atranscytosis +
                                                is-atransepithelial transport +
                                                is-atransmembrane transport +
                                                is-atRNA transport +
                                                is-aubiquitin-dependent endocytosis +
                                                is-avascular transport +
                                                is-avesicle transport along actin filament
                                                is-avesicle-mediated transport involved in floral organ abscission +
                                                is-avitamin transport +
                                                is-axenobiotic transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-avesicle-mediated transport
                                                is-aendocytosis
                                                        is-aendocytosis involved in viral entry into host cell +
                                                        negatively-regulatesnegative regulation of endocytosis +
                                                        is-aphagocytosis [GO:0006909] (114 genes, 183 annotations)
                                                                is-aapoptotic cell clearance +
                                                                part-ofFc-gamma receptor signaling pathway involved in phagocytosis
                                                                part-ofimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                                                negatively-regulatesnegative regulation of phagocytosis +
                                                                part-ofopsonization +
                                                                part-ofphagocytosis, engulfment +
                                                                part-ofphagocytosis, recognition +
                                                                part-ofphagolysosome assembly +
                                                                positively-regulatespositive regulation of phagocytosis +
                                                                regulatesregulation of phagocytosis +
                                                        is-apinocytosis +
                                                        positively-regulatespositive regulation of endocytosis +
                                                        is-areceptor-mediated endocytosis +
                                                        regulatesregulation of endocytosis +
                                                        is-asperm entry
                                                        is-asynaptic vesicle endocytosis +
                                                        is-aubiquitin-dependent endocytosis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-a2-aminoethylphosphonate transport
                                is-aacetate ester transport +
                                is-aalkane transport
                                is-aamide transport +
                                is-aamine transport +
                                is-acarbohydrate derivative transport +
                                is-acarbohydrate transport +
                                is-acargo loading into vesicle +
                                is-achaperone-mediated protein transport +
                                is-acofactor transport +
                                is-acutin transport
                                is-aDNA import into cell involved in transformation
                                is-adrug transport +
                                is-adsRNA transport
                                is-aeye pigment precursor transport
                                is-afatty acid derivative transport +
                                is-afatty-acyl group transport
                                is-afluid transport +
                                is-agas transport +
                                is-aglycoside transport +
                                is-ahormone transport +
                                is-ahydrogen transport +
                                is-aion transport +
                                is-airon coordination entity transport +
                                is-alactone transport
                                is-alipid hydroperoxide transport
                                is-alipid transport +
                                is-alipoprotein transport
                                is-amonoamine transport +
                                is-amultivesicular body sorting pathway
                                is-aneurotransmitter transport +
                                is-anitric oxide transport
                                is-anucleobase transport +
                                is-aone-carbon compound transport +
                                is-aorganic acid transport +
                                is-aorganic hydroxy compound transport +
                                is-aorganic phosphonate transport +
                                is-aorganophosphate ester transport +
                                is-aovarian nurse cell to oocyte transport +
                                is-aphagocytosis [GO:0006909] (114 genes, 183 annotations)
                                        is-aapoptotic cell clearance +
                                        part-ofFc-gamma receptor signaling pathway involved in phagocytosis
                                        part-ofimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                        negatively-regulatesnegative regulation of phagocytosis +
                                        part-ofopsonization +
                                        part-ofphagocytosis, engulfment +
                                        part-ofphagocytosis, recognition +
                                        part-ofphagolysosome assembly +
                                        positively-regulatespositive regulation of phagocytosis +
                                        regulatesregulation of phagocytosis +
                                is-apigment granule transport +
                                is-apolyamine transport +
                                is-aprotein import +
                                is-aprotein transport across periplasmic space +
                                is-aprotein transport within extracellular region
                                is-aquaternary ammonium group transport +
                                is-areceptor internalization +
                                is-areceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
                                is-arRNA transport +
                                is-asecretion +
                                is-asilicate transport +
                                is-asingle-organism intercellular transport +
                                is-asingle-organism intracellular transport +
                                is-asingle-organism pinocytosis +
                                is-asnRNA transport +
                                is-asperm entry
                                is-asulfur compound transport +
                                is-asynaptic vesicle transport +
                                is-athioester transport +
                                is-atranscytosis +
                                is-atransepithelial transport +
                                is-atransmembrane transport +
                                is-atRNA transport +
                                is-aubiquitin-dependent endocytosis +
                                is-avascular transport +
                                is-avesicle transport along actin filament
                                is-avesicle-mediated transport involved in floral organ abscission +
                                is-avitamin transport +
                                is-axenobiotic transport +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory