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Term Detail
GO term:GTPase activator activity
Synonym: ARF GAP activity
Synonym: ARF GTPase activator activity
Synonym: GAP activity
Synonym: Rab GAP activity
Synonym: Rab GTPase activator activity
Synonym: Rac GAP activity
Synonym: Rac GTPase activator activity
Synonym: Ral GAP activity
Synonym: Ral GTPase activator activity
Synonym: RanGAP
Synonym: Ran GAP activity
Synonym: Ran GTPase activator activity
Synonym: Rap GAP activity
Synonym: Rap GTPase activator activity
Synonym: Ras GAP activity
Synonym: Ras GTPase activator activity
Synonym: Rho GAP activity
Synonym: Rho GTPase activator activity
Synonym: Sar GAP activity
Synonym: Sar GTPase activator activity
GO id:GO:0005096
Alternate id: GO:0046582, GO:0005098, GO:0005100, GO:0008060, GO:0005097, GO:0005099, GO:0005101, GO:0017123, GO:0030675
Definition:Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
CommentsNote that the name Sar derives from ''secretion-associated, Ras-related''.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-aenzyme activator activity
                                is-aacetyltransferase activator activity
                                is-aATPase activator activity +
                                is-aexoribonuclease activator activity
                                is-aGTPase activator activity [GO:0005096] (197 genes, 242 annotations)
                                is-aguanylate cyclase activator activity +
                                is-akinase activator activity +
                                is-aL-dopa decarboxylase activator activity
                                is-alipase activator activity +
                                is-am7G(5')pppN diphosphatase activator activity
                                is-ametalloenzyme activator activity
                                is-aornithine decarboxylase activator activity
                                is-apeptidase activator activity +
                                is-aphosphatase activator activity +
                                is-aphosphatidylcholine-sterol O-acyltransferase activator activity
                                is-aribulose-1,5-bisphosphate carboxylase/oxygenase activator activity
                                is-aRNA lariat debranching enzyme activator activity
                                is-asingle-stranded DNA endodeoxyribonuclease activator activity
                                is-asphingolipid activator protein activity
                                is-asuperoxide dismutase copper chaperone activity
                                is-asuperoxide-generating NADPH oxidase activator activity
                                is-atryptophan hydroxylase activator activity
                                is-atyrosine 3-monooxygenase activator activity
                                is-aurease activator activity


Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-anucleoside-triphosphatase regulator activity
                                is-aGTPase regulator activity
                                        is-aGDP-dissociation inhibitor activity +
                                        is-aGTPase activator activity [GO:0005096] (197 genes, 242 annotations)
                                        is-aGTPase inhibitor activity
                                        is-aguanyl-nucleotide exchange factor adaptor activity
                                        is-aSar guanyl-nucleotide exchange factor activity


Gene_Ontology
        is-amolecular_function
                is-amolecular function regulator
                        is-aenzyme regulator activity
                                is-aenzyme activator activity
                                        is-aacetyltransferase activator activity
                                        is-aATPase activator activity +
                                        is-aexoribonuclease activator activity
                                        is-aGTPase activator activity [GO:0005096] (197 genes, 242 annotations)
                                        is-aguanylate cyclase activator activity +
                                        is-akinase activator activity +
                                        is-aL-dopa decarboxylase activator activity
                                        is-alipase activator activity +
                                        is-am7G(5')pppN diphosphatase activator activity
                                        is-ametalloenzyme activator activity
                                        is-aornithine decarboxylase activator activity
                                        is-apeptidase activator activity +
                                        is-aphosphatase activator activity +
                                        is-aphosphatidylcholine-sterol O-acyltransferase activator activity
                                        is-aribulose-1,5-bisphosphate carboxylase/oxygenase activator activity
                                        is-aRNA lariat debranching enzyme activator activity
                                        is-asingle-stranded DNA endodeoxyribonuclease activator activity
                                        is-asphingolipid activator protein activity
                                        is-asuperoxide dismutase copper chaperone activity
                                        is-asuperoxide-generating NADPH oxidase activator activity
                                        is-atryptophan hydroxylase activator activity
                                        is-atyrosine 3-monooxygenase activator activity
                                        is-aurease activator activity


Gene_Ontology
        is-amolecular_function
                is-amolecular function regulator
                        is-aenzyme regulator activity
                                is-anucleoside-triphosphatase regulator activity
                                        is-aGTPase regulator activity
                                                is-aGDP-dissociation inhibitor activity +
                                                is-aGTPase activator activity [GO:0005096] (197 genes, 242 annotations)
                                                is-aGTPase inhibitor activity
                                                is-aguanyl-nucleotide exchange factor adaptor activity
                                                is-aSar guanyl-nucleotide exchange factor activity


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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory