Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARNT
  • Mouse genes Arnt
  • Rat genes Arnt
  • Zfish genes arnt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arnt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017162	aryl hydrocarbon receptor binding	ARNT	IPI	UniProtKB:P35869	Human	PMID:9079689
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ARNT	IDA		Human	PMID:23275542
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ARNT	IDA		Human	PMID:29454749
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Arnt	IDA		Mouse	MGI:MGI:6158748|PMID:28602820
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Arnt	IDA		Mouse	PMID:15363889
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ARNT	IDA		Human	PMID:7539918
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ARNT	IDA		Human	PMID:8756616
Molecular Function	GO:0004879	nuclear receptor activity	ARNT	IDA		Human	PMID:34521881
Molecular Function	GO:0004879	nuclear receptor activity	Arnt	IMP	MGI:MGI:2176696	Mouse	PMID:11043581
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:P35869	Human	PMID:10395741
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q8NI08	Human	PMID:10395741
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q9Y618	Human	PMID:10395741
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:11018023
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:14668441
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:14668441
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:16181639
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:19129502
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:20603618
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:20932347
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:21620138
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:23434853
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:24434214
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:P30561	Human	PMID:28396409
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:P35869	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:P35869	Human	PMID:34521881
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:P35869	Human	PMID:9704006
Molecular Function	GO:0005515	protein binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:9704006
Molecular Function	GO:0005515	protein binding	Arnt	IPI	UniProtKB:Q61045	Mouse	MGI:MGI:86070|PMID:9020169
Molecular Function	GO:0005515	protein binding	Arnt	IPI	UniProtKB:P30561	Mouse	MGI:MGI:5547895|PMID:24001774
Molecular Function	GO:0005515	protein binding	Arnt	IPI	UniProtKB:Q61045	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Arnt	IPI	UniProtKB:Q16665	Mouse	PMID:9113979
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:P97459	Mouse	PMID:27782878
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:Q61221	Mouse	PMID:20440072
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:P30561	Mouse	PMID:27782878
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:Q61221	Mouse	PMID:8702901
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:P30561	Mouse	PMID:28602820
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:Q61221	Mouse	PMID:26245371
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:P97481	Mouse	PMID:9113979
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:Q61079	Mouse	PMID:11782478
Molecular Function	GO:0005515	protein binding	Arnt	IPI	PR:P97481	Mouse	PMID:26245371
Molecular Function	GO:0005515	protein binding	Arnt	IPI	UniProtKB:P41738	Rat	PMID:11259609|RGD:8554020
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT	IDA		Human	PMID:16181639
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT	IDA		Human	PMID:34521881
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT	IPI	UniProtKB:Q16665	Human	PMID:9079689
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT	IPI	UniProtKB:Q99814	Human	PMID:9079689
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt	IDA		Mouse	MGI:MGI:5927132|PMID:26245371
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt	IDA		Mouse	MGI:MGI:5547895|PMID:24001774
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt	IDA		Mouse	MGI:MGI:5824181|PMID:27782878
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt	IDA		Mouse	MGI:MGI:6158748|PMID:28602820
Molecular Function	GO:0042803	protein homodimerization activity	ARNT	IDA		Human	PMID:16181639
Molecular Function	GO:0044877	protein-containing complex binding	Arnt	IDA		Rat	PMID:11029639|RGD:2301215
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Arnt	IGI	UniProtKB:Q99814	Mouse	PMID:9000051
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Arnt	IGI	MGI:MGI:109169	Mouse	PMID:9113979
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Arnt	IGI	MGI:MGI:106918	Mouse	PMID:9113979
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ARNT	IPI	UniProtKB:Q9UBP5	Human	PMID:10692439
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ARNT	IPI	UniProtKB:Q9Y5J3	Human	PMID:10692439
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ARNT	IPI	UniProtKB:Q16665	Human	PMID:7539918
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ARNT	IPI	UniProtKB:Q99814	Human	PMID:9079689
Molecular Function	GO:0043565	sequence-specific DNA binding	ARNT	IDA		Human	PMID:7539918
Molecular Function	GO:0043565	sequence-specific DNA binding	Arnt	IDA		Mouse	MGI:MGI:5927132|PMID:26245371
Molecular Function	GO:0043565	sequence-specific DNA binding	Arnt	IDA		Rat	PMID:11029639|RGD:2301215
Molecular Function	GO:0043565	sequence-specific DNA binding	arnt	IPI	UniProtKB:Q45FA8,UniProtKB:Q9YGV3	Zfish	PMID:16306231
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ARNT	IDA		Human	PMID:28396409
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ARNT	IDA		Human	PMID:34521881
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	Arnt	IDA		Mouse	MGI:MGI:6158748|PMID:28602820
Cellular Component	GO:0005737	cytoplasm	Arnt	IDA		Mouse	PMID:11074397
Cellular Component	GO:0005737	cytoplasm	Arnt	IDA		Mouse	PMID:11025203
Cellular Component	GO:0034753	nuclear aryl hydrocarbon receptor complex	ARNT	IDA		Human	PMID:34521881
Cellular Component	GO:0016604	nuclear body	ARNT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ARNT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ARNT	IDA		Human	PMID:34521881
Cellular Component	GO:0005634	nucleus	ARNT	IDA		Human	PMID:8089148
Cellular Component	GO:0005634	nucleus	Arnt	IDA		Mouse	PMID:20440072
Cellular Component	GO:0005634	nucleus	Arnt	IDA		Mouse	PMID:15016652
Cellular Component	GO:0005634	nucleus	Arnt	IDA		Mouse	PMID:11025203
Cellular Component	GO:0005634	nucleus	Arnt	IDA		Mouse	PMID:11074397
Cellular Component	GO:0005634	nucleus	Arnt	IDA		Rat	PMID:10873592|RGD:2301216
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ARNT	IDA		Human	PMID:7539918
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ARNT	IDA		Human	PMID:8756616
Cellular Component	GO:0005667	transcription regulator complex	Arnt	IDA		Mouse	PMID:9000051
Biological Process	GO:0030154	cell differentiation	Arnt	IMP	MGI:MGI:1857680	Mouse	PMID:16287860
Biological Process	GO:0001892	embryonic placenta development	Arnt	IMP	MGI:MGI:1857680	Mouse	PMID:16287860
Biological Process	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	arnt	IMP	ZFIN:ZDB-GENO-210721-3	Zfish	PMID:32379754
Biological Process	GO:0050728	negative regulation of inflammatory response	ARNT	IDA		Human	PMID:29454749
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Arnt	IDA		Mouse	PMID:15363889
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	arnt	IPI	UniProtKB:Q64FF8,UniProtKB:Q9YGV3	Zfish	PMID:16306231
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	arnt	IPI	UniProtKB:Q45FA8,UniProtKB:Q9YGV3	Zfish	PMID:16306231
Biological Process	GO:0046886	positive regulation of hormone biosynthetic process	ARNT	IDA		Human	PMID:1448077
Biological Process	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	arnt	IGI	ZFIN:ZDB-GENO-210721-1	Zfish	PMID:32379754
Biological Process	GO:0033235	positive regulation of protein sumoylation	Arnt	IDA		Mouse	MGI:MGI:4359338|PMID:19251700
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ARNT	IDA		Human	PMID:34521881
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ARNT	IDA		Human	PMID:7539918
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ARNT	IDA		Human	PMID:8089148
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:97858	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:106918	Mouse	PMID:9113979
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:109169	Mouse	PMID:9113979
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:97857	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	UniProtKB:Q99814	Mouse	PMID:9000051
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:106918	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt	IGI	MGI:MGI:97856	Mouse	PMID:15766748
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	ARNT	IDA		Human	PMID:8756616
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	ARNT	IDA		Human	PMID:8089148
Biological Process	GO:0071548	response to dexamethasone	Arnt	IEP		Rat	PMID:27856527|RGD:127285625
Biological Process	GO:0001666	response to hypoxia	ARNT	IDA		Human	PMID:8756616
Biological Process	GO:0001666	response to hypoxia	Arnt	IDA		Mouse	PMID:8702901
Biological Process	GO:0001666	response to hypoxia	Arnt	IEP		Rat	PMID:10873592|RGD:2301216
Biological Process	GO:0009636	response to toxic substance	arnt	IMP	ZFIN:ZDB-MRPHLNO-060126-2	Zfish	PMID:16936225
Biological Process	GO:0009410	response to xenobiotic stimulus	arnt	IPI	UniProtKB:Q64FF8,UniProtKB:Q9YGV3	Zfish	PMID:16306231
Biological Process	GO:0009410	response to xenobiotic stimulus	arnt	IPI	UniProtKB:Q45FA8,UniProtKB:Q9YGV3	Zfish	PMID:16306231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern