| GO term: | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
| Synonym: | ligand-dependent nuclear receptor activity |
| Synonym: | ligand-dependent transcription factor activity |
| Synonym: | nuclear hormone receptor |
| Synonym: | nuclear receptor activity |
| GO id: | GO:0004879 |
| Definition: | Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. |
| Comments | GO:0004879 is intended for annotation of nuclear receptors that regulate transcription by binding directly to DNA. When the nuclear receptor functions by binding to other transcription factors or transcription factor complexes, consider instead annotating to 'ligand-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038049'. |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activityleucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [GO:0004879] (40 genes, 59 annotations)androgen receptor activityecdysteroid hormone receptor activityestrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activityglucocorticoid-activated sequence-specific DNA binding RNA polymerase II transcription factor activityjuvenile hormone receptor activitymineralocorticoid receptor activityretinoic acid receptor activity +thyroid hormone receptor activityvitamin D3 receptor activityneurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity +U-plasminogen activator receptor activitymolecular_functionnucleic acid binding transcription factor activitysequence-specific DNA binding transcription factor activitysequence-specific DNA binding RNA polymerase II transcription factor activityligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [GO:0004879] (40 genes, 59 annotations)androgen receptor activityecdysteroid hormone receptor activityestrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activityglucocorticoid-activated sequence-specific DNA binding RNA polymerase II transcription factor activityjuvenile hormone receptor activitymineralocorticoid receptor activityretinoic acid receptor activity +thyroid hormone receptor activityvitamin D3 receptor activitymetal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity +RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity +RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity +RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity +RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription +RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription +molecular_functionreceptor activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activityleucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [GO:0004879] (40 genes, 59 annotations)androgen receptor activityecdysteroid hormone receptor activityestrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activityglucocorticoid-activated sequence-specific DNA binding RNA polymerase II transcription factor activityjuvenile hormone receptor activitymineralocorticoid receptor activityretinoic acid receptor activity +thyroid hormone receptor activityvitamin D3 receptor activityneurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity +U-plasminogen activator receptor activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 05/08/2013 MGI 5.13 |
|
|
|
||
Analysis Tools