Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADGRB1
  • Mouse genes Adgrb1
  • Rat genes Adgrb1
  • Zfish genes adgrb1a,adgrb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adgrb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	ADGRB1	IDA		Human	PMID:23782696
Molecular Function	GO:0001530	lipopolysaccharide binding	Adgrb1	IDA		Mouse	MGI:MGI:4939876|PMID:21245295
Molecular Function	GO:0030165	PDZ domain binding	Adgrb1	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5521259|PMID:23782696
Molecular Function	GO:0001786	phosphatidylserine binding	Adgrb1	IDA		Mouse	MGI:MGI:3764740|PMID:17960134
Molecular Function	GO:0005515	protein binding	ADGRB1	IPI	UniProtKB:Q92556-1	Human	PMID:17960134
Molecular Function	GO:0005515	protein binding	ADGRB1	IPI	UniProtKB:O94812	Human	PMID:9790924
Molecular Function	GO:0005515	protein binding	Adgrb1	IPI	UniProtKB:Q92556-1	Mouse	MGI:MGI:3764740|PMID:17960134
Molecular Function	GO:0005515	protein binding	Adgrb1	IPI	UniProtKB:P23804	Mouse	MGI:MGI:5643972|PMID:25751059
Molecular Function	GO:0005515	protein binding	Adgrb1	IPI	UniProtKB:Q8BPU7|UniProtKB:Q8BUR4	Mouse	MGI:MGI:3764740|PMID:17960134
Molecular Function	GO:0005515	protein binding	Adgrb1	IPI	PR:Q8K0S0	Mouse	PMID:11245925
Molecular Function	GO:0005515	protein binding	Adgrb1	IPI	RGD:1307455	Rat	PMID:23595754|RGD:13831359
Molecular Function	GO:0004888	transmembrane signaling receptor activity	Adgrb1	IDA		Mouse	MGI:MGI:3764740|PMID:17960134
Cellular Component	GO:0030425	dendrite	Adgrb1	IDA		Mouse	MGI:MGI:5908337|PMID:20888903
Cellular Component	GO:0005615	extracellular space	ADGRB1	IDA		Human	PMID:15782143
Cellular Component	GO:0005615	extracellular space	ADGRB1	IDA		Human	PMID:22330140
Cellular Component	GO:0005925	focal adhesion	Adgrb1	IDA		Mouse	MGI:MGI:5908337|PMID:20888903
Cellular Component	GO:0098978	glutamatergic synapse	Adgrb1	IDA		Rat	PMID:23595754|RGD:13831359
Cellular Component	GO:0098978	glutamatergic synapse	Adgrb1	IMP		Rat	PMID:23595754|RGD:13831359
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ADGRB1	IDA		Human	PMID:26838550
Cellular Component	GO:0001891	phagocytic cup	Adgrb1	IDA		Mouse	MGI:MGI:3764740|PMID:17960134
Cellular Component	GO:0005886	plasma membrane	ADGRB1	IDA		Human	PMID:26838550
Cellular Component	GO:0005886	plasma membrane	Adgrb1	IDA		Mouse	MGI:MGI:3764740|PMID:17960134
Cellular Component	GO:0005886	plasma membrane	Adgrb1	IDA		Mouse	MGI:MGI:5908337|PMID:20888903
Cellular Component	GO:0014069	postsynaptic density	Adgrb1	IDA		Mouse	MGI:MGI:5490407|PMID:23595754
Cellular Component	GO:0014069	postsynaptic density	Adgrb1	IDA		Mouse	MGI:MGI:5521259|PMID:23782696
Cellular Component	GO:0045211	postsynaptic membrane	Adgrb1	IDA		Rat	PMID:23595754|RGD:13831359
Cellular Component	GO:0045211	postsynaptic membrane	Adgrb1	IMP		Rat	PMID:23595754|RGD:13831359
Biological Process	GO:0043277	apoptotic cell clearance	ADGRB1	IMP		Human	PMID:24509909
Biological Process	GO:0043277	apoptotic cell clearance	adgrb1b	IMP	ZFIN:ZDB-MRPHLNO-160413-3,ZFIN:ZDB-MRPHLNO-160413-4	Zfish	PMID:24898390
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Adgrb1	IMP		Mouse	MGI:MGI:4939876|PMID:21245295
Biological Process	GO:0043652	engulfment of apoptotic cell	ADGRB1	IMP		Human	PMID:24509909
Biological Process	GO:0043652	engulfment of apoptotic cell	Adgrb1	IDA		Mouse	MGI:MGI:3764740|PMID:17960134
Biological Process	GO:0043652	engulfment of apoptotic cell	adgrb1b	IMP	ZFIN:ZDB-MRPHLNO-160413-3,ZFIN:ZDB-MRPHLNO-160413-4	Zfish	PMID:24898390
Biological Process	GO:0016525	negative regulation of angiogenesis	ADGRB1	IDA		Human	PMID:15782143
Biological Process	GO:0016525	negative regulation of angiogenesis	ADGRB1	IDA		Human	PMID:19176395
Biological Process	GO:0016525	negative regulation of angiogenesis	ADGRB1	IDA		Human	PMID:22330140
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ADGRB1	IDA		Human	PMID:15782143
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ADGRB1	IDA		Human	PMID:19176395
Biological Process	GO:0042177	negative regulation of protein catabolic process	Adgrb1	IMP		Mouse	MGI:MGI:5643972|PMID:25751059
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Adgrb1	IMP		Mouse	MGI:MGI:5643972|PMID:25751059
Biological Process	GO:0006911	phagocytosis, engulfment	Adgrb1	IMP		Mouse	MGI:MGI:5908515|PMID:26838550
Biological Process	GO:0006910	phagocytosis, recognition	Adgrb1	IMP		Mouse	MGI:MGI:4939876|PMID:21245295
Biological Process	GO:0090387	phagolysosome assembly involved in apoptotic cell clearance	adgrb1b	IMP	ZFIN:ZDB-MRPHLNO-160413-3,ZFIN:ZDB-MRPHLNO-160413-4	Zfish	PMID:24898390
Biological Process	GO:1901741	positive regulation of myoblast fusion	Adgrb1	IMP		Mouse	MGI:MGI:5498642|PMID:23615608
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	ADGRB1	IMP		Human	PMID:26838550
Biological Process	GO:0051965	positive regulation of synapse assembly	Adgrb1	IDA		Mouse	PMID:24613359
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Adgrb1	IDA		Rat	PMID:23595754|RGD:13831359
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Adgrb1	IMP		Rat	PMID:23595754|RGD:13831359
Biological Process	GO:0048167	regulation of synaptic plasticity	Adgrb1	IMP		Mouse	MGI:MGI:5643972|PMID:25751059

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern