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Adgrb1 Gene Detail
Summary
  • Symbol
    Adgrb1
  • Name
    adhesion G protein-coupled receptor B1
  • Synonyms
    B830018M07Rik, Bai1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933736
    NCBI Gene: 107831
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:74516195-74589465 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      73271 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 34.22 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ADGRB1, adhesion G protein-coupled receptor B1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ADGRB1, adhesion G protein-coupled receptor B1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAI1, GDAIF
  • Links
    NCBI Gene ID: 575
    neXtProt AC: NX_O14514
    UniProt: O14514

  • Chr Location
    8q24.3; chr8:142449703-142545009 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    34 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000045270 VEGA Gene Model | MGI Sequence Detail 73271 C57BL/6J ±  kb
    transcript OTTMUST00000118895 VEGA | MGI Sequence Detail 6228 Not Applicable  
    polypeptide OTTMUSP00000066298 VEGA | MGI Sequence Detail 1582 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      454 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      13 Sequences
    • Protein Ontology
      PR:000004629 brain-specific angiogenesis inhibitor 1
    • InterPro Domains
      IPR032471 GAIN domain, N-terminal
      IPR008077 GPCR, family 2, brain-specific angiogenesis inhibitor
      IPR001879 GPCR, family 2, extracellular hormone receptor domain
      IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
      IPR017981 GPCR, family 2-like
      IPR000832 GPCR, family 2, secretin-like
      IPR000203 GPS motif
      IPR000884 Thrombospondin type-1 (TSP1) repeat
      IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
    Molecular
    Reagents
    less
    • All nucleic 40
      Genomic 1
      cDNA 36
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2146318
    References
    more
    • Summaries
      All 71
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 13
      Phenotypes 34
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:243461 Billings EA, et al., The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria. Sci Signal. 2016 Feb 02;9(413):ra14

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory