About   Help   FAQ
Adgrb1 Gene Detail
Summary
  • Symbol
    Adgrb1
  • Name
    adhesion G protein-coupled receptor B1
  • Synonyms
    B830018M07Rik, Bai1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933736
    NCBI Gene: 107831
Location & Maps
more
  • Sequence Map
    Chr15:74516195-74589465 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      73271 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ADGRB1, adhesion G protein-coupled receptor B1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ADGRB1, adhesion G protein-coupled receptor B1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BAI1, GDAIF
  • Links
    NCBI Gene ID: 575
    neXtProt AC: NX_O14514

  • Chr Location
    8q24.3; chr8:142449888-142545008 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 2 genetic backgrounds
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    5 involving Adgrb1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045270 VEGA Gene Model | MGI Sequence Detail 73271 C57BL/6J ±  kb
transcript OTTMUST00000118895 VEGA | MGI Sequence Detail 6228 Not Applicable  
polypeptide OTTMUSP00000066298 VEGA | MGI Sequence Detail 1582 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    454 from dbSNP Build 137
Protein
Information
less
  • UniProt
    13 Sequences
  • Protein Ontology
    PR:000004629 brain-specific angiogenesis inhibitor 1
  • InterPro Domains
    IPR032471 GAIN domain, N-terminal
    IPR008077 GPCR, family 2, brain-specific angiogenesis inhibitor
    IPR001879 GPCR, family 2, extracellular hormone receptor domain
    IPR017981 GPCR, family 2-like
    IPR000832 GPCR, family 2, secretin-like
    IPR000203 GPS motif
    IPR000884 Thrombospondin type-1 (TSP1) repeat
Molecular
Reagents
less
  • All nucleic 40
    Genomic 1
    cDNA 36
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146318
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 6
    Phenotypes 28
  • Earliest
    J:68103 Koh JT, et al., Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein. Brain Res Mol Brain Res. 2001 Mar 5;87(2):223-37
  • Latest
    J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory