| GO term: | transmembrane signaling receptor activity |
| Synonym: | non G protein coupled 7TM receptor activity |
| Synonym: | non-G-protein coupled 7TM receptor activity |
| Synonym: | non-G-protein-coupled 7TM receptor activity |
| Synonym: | transmembrane receptor activity |
| Synonym: | transmembrane signalling receptor activity |
| GO id: | GO:0004888 |
| Definition: | Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| Comments | 'Transmembrane' in the term name refers to the mechanism of transmitting the signal across the membrane, rather than the subcellular location of the receptor. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activityleucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity +neurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity [GO:0004888] (2084 genes, 3995 annotations)acetylcholine receptor activity +apolipoprotein A-I receptor activityaxon guidance receptor activitycollagen receptor activity +complement receptor activity +cytokine receptor activity +cytokinin receptor activity +death receptor activity +G-protein coupled receptor activity +GABA receptor activity +glutamate receptor activity +hedgehog receptor activityICAM-3 receptor activityimmunoglobulin receptor activity +latrotoxin receptor activityMHC class I receptor activity +MHC class Ib receptor activityMHC class II receptor activitynetrin receptor activity +neuregulin receptor activityneurotensin receptor activity, non-G-protein couplednon-tyrosine kinase fibroblast growth factor receptor activitynucleotide receptor activity +olfactory receptor activity +opsonin receptor activity +osmosensor activitypurinergic receptor activity +reelin receptor activitysemaphorin receptor activitysulfonylurea receptor activitytiggrin receptor activitytransmembrane receptor protein kinase activity +transmembrane receptor protein phosphatase activity +Wnt-activated receptor activityU-plasminogen activator receptor activitymolecular_functionreceptor activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activityleucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity +neurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity [GO:0004888] (2084 genes, 3995 annotations)acetylcholine receptor activity +apolipoprotein A-I receptor activityaxon guidance receptor activitycollagen receptor activity +complement receptor activity +cytokine receptor activity +cytokinin receptor activity +death receptor activity +G-protein coupled receptor activity +GABA receptor activity +glutamate receptor activity +hedgehog receptor activityICAM-3 receptor activityimmunoglobulin receptor activity +latrotoxin receptor activityMHC class I receptor activity +MHC class Ib receptor activityMHC class II receptor activitynetrin receptor activity +neuregulin receptor activityneurotensin receptor activity, non-G-protein couplednon-tyrosine kinase fibroblast growth factor receptor activitynucleotide receptor activity +olfactory receptor activity +opsonin receptor activity +osmosensor activitypurinergic receptor activity +reelin receptor activitysemaphorin receptor activitysulfonylurea receptor activitytiggrin receptor activitytransmembrane receptor protein kinase activity +transmembrane receptor protein phosphatase activity +Wnt-activated receptor activityU-plasminogen activator receptor activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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