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All mouse models of metal metabolism disorder with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | acrodermatitis enteropathica |
Slc39a4tm2Gka/Slc39a4tm2Gka Tg(Vil1-cre/ERT2)23Syr/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:187178 | View | |||
| Albright's hereditary osteodystrophy | Gnastm1Gwa/Gnas+ | involves: 129S/SvEv * 129S4/SvJae | J:174525 | View | ||||
| Albright's hereditary osteodystrophy | Gnastm4Lsw/Gnas+ | involves: 129S6/SvEvTac | J:233851 | View | ||||
| atransferrinemia | Trfhpx/Trf+ | BALB/cJ-Trfhpx | J:64456, J:8936 | View | ||||
| atransferrinemia | Trfhpx/Trfhpx | BALB/cJ-Trfhpx | J:64456, J:8936 | View | ||||
| autosomal dominant hypocalcemia 1 | CasrNuf/Casr+ | either: (involves: 102/El * 102/H * C3H/He) or (involves: 102/El * C3H/He * C3H/HeH) | J:92612 | View | ||||
| autosomal dominant hypocalcemia 1 | CasrNuf/CasrNuf | involves: 102/El * C3H/He | J:92612 | View | ||||
| autosomal dominant hypocalcemia 2 | Gna11em1Mman/Gna11+ | C57BL/6NCrl-Gna11em1Mman | J:280180 | View | ||||
| autosomal dominant hypocalcemia 2 | Gna11em1Mman/Gna11em1Mman | C57BL/6NCrl-Gna11em1Mman | J:280180 | View | ||||
| hemochromatosis type 1 | Hfetm1.1Gfn/Hfetm1.1Gfn | B6.129P2-Hfetm1.1Gfn | J:114351 | View | ||||
| hemochromatosis type 1 | Hfetm1.1Nca/Hfetm1.1Nca | involves: 129S6/SvEvTac | J:78536 | View | ||||
| hemochromatosis type 1 | Hfetm1.1Nca/Hfetm1.1Nca | involves: 129S6/SvEvTac * C57BL/6J | J:78536 | View | ||||
| hemochromatosis type 1 | Hfetm1.1Nca/Hfetm1.1Nca | Not Specified | J:62112 | View | ||||
| hemochromatosis type 1 | Hfetm1.1Wsr/Hfetm1.1Wsr | involves: 129P2/OlaHsd * C57BL/6 | J:141745 | View | ||||
| hemochromatosis type 1 | Hfetm1Gfn/Hfetm1Gfn | involves: 129P2/OlaHsd * C57BL/6 | J:68025, J:262906 | View | ||||
| hemochromatosis type 1 | Hfetm1Sly/Hfetm1Sly | Not Specified | J:88143 | View | ||||
| hemochromatosis type 1 | Hfetm1Sly/Hfetm2Sly | involves: 129X1/SvJ * C57BL/6J | J:88143 | View | ||||
| hemochromatosis type 1 | Hfetm2Nca/Hfetm2Nca | involves: 129S6/SvEvTac | J:78536, J:62112 | View | ||||
| hemochromatosis type 1 | Hfetm2Nca/Hfetm2Nca | involves: 129S6/SvEvTac * C57BL/6J | J:78536 | View | ||||
| hemochromatosis type 1 | Hfetm2Sly/Hfetm2Sly | involves: 129X1/SvJ * C57BL/6J | J:88143 | View | ||||
| hemochromatosis type 1 | Hfetm2Sly/Hfetm3Sly | involves: 129X1/SvJ * C57BL/6J | J:88143 | View | ||||
| hemochromatosis type 1 | Hfetm3Sly/Hfetm3Sly | involves: 129X1/SvJ * C57BL/6J | J:88143 | View | ||||
| hemochromatosis type 2A | Hjvtm1Arbr/Hjvtm1Arbr | involves: 129S4/SvJae * 129X1/SvJ | J:100173 | View | ||||
| hemochromatosis type 2A | Hjvtm1Nca/Hjvtm1Nca | involves: 129S4/SvJae * 129S6/SvEvTac | J:100178 | View | ||||
| hemochromatosis type 2B | Hamptm1Svl/Hamptm1Svl | involves: 129S2/SvPas * C57BL/6 | J:119004 | View | ||||
| hemochromatosis type 3 | Tfr2tm1.1Anro/Tfr2tm1.1Anro | 129.Cg-Tfr2tm1.1Anro | J:160785 | View | ||||
| hemochromatosis type 3 | Tfr2tm1Slu/Tfr2tm1Slu | involves: 129X1/SvJ * C57BL/6J | J:78360 | View | ||||
| hemochromatosis type 4 | Slc40a1ffe/Slc40a1+ | either: (involves: 129X1/SvJ * C57BL/6J) or (involves: C3H/HeJ * C57BL/6J) | J:118592 | View | ||||
| hemochromatosis type 4 | Slc40a1tm1.1Mmfe/Slc40a1+ | involves: 129P2/OlaHsd * C57BL/6 | J:215585 | View | ||||
| hemochromatosis type 4 | Slc40a1tm1.1Mmfe/Slc40a1tm1.1Mmfe | involves: 129P2/OlaHsd * C57BL/6 | J:215585 | View | ||||
| hyperkalemic periodic paralysis | Scn4atm1.1Ljh/Scn4a+ | B6.129S4-Scn4atm1.1Ljh | J:135831 | View | ||||
| hyperkalemic periodic paralysis | Scn4atm1.1Ljh/Scn4atm1.1Ljh | B6.129S4-Scn4atm1.1Ljh | J:135831 | View | ||||
| hyperkalemic periodic paralysis | Scn4atm1Ljh/Scn4a+ | B6.129S4-Scn4atm1Ljh | J:135831 | View | ||||
| hyperkalemic periodic paralysis | Scn4atm1Ljh/Scn4atm1Ljh | B6.129S4-Scn4atm1Ljh | J:135831 | View | ||||
| hypokalemic periodic paralysis | Cacna1stm1.1Cann/Cacna1s+ | involves: 129 | J:193967 | View | ||||
| hypokalemic periodic paralysis | Cacna1stm1.1Cann/Cacna1stm1.1Cann | involves: 129 | J:19367 | View | ||||
| Menkes disease | Atp7aMo-blo/Atp7a+ | involves: C57BL/6J | J:36268 | View | ||||
| Menkes disease | Atp7aMo-blo/Y | involves: C57BL/6J | J:36268 | View | ||||
| Menkes disease | Atp7aMo-br/Y | involves: C57BL | J:5462 | View | ||||
| Menkes disease | Atp7aMo-dp/Atp7a+ | involves: 101/H * C3H/HeH | J:220263 | View | ||||
| Menkes disease | Atp7aMo-dp/Y | involves: 101/H * C3H/HeH | J:220263 | View | ||||
| Menkes disease | Atp7aMo-ml/Y | involves: C3Hf/He | J:1132, J:12745 | View | ||||
| Menkes disease | Atp7aMo-ms/Y | Not Specified | J:168658 | View | ||||
| Menkes disease | Atp7aMo-Tohm/Atp7a+ | B6.Cg-Atp7aMo-Tohm | J:105797 | View | ||||
| Menkes disease | Atp7aMo-vbr/Y | Not Specified | J:53559 | View | ||||
| Menkes disease | Atp7aMo/Atp7a+ | Not Specified | J:249 | View | ||||
| Menkes disease | Loxtm1Ikh/Loxtm1Ikh | involves: 129X1/SvJ * C57BL/6J | J:82926 | View | ||||
| molybdenum cofactor deficiency type A | Mocs1tm1Jre/Mocs1tm1Jre | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:80807 | View | ||||
| molybdenum cofactor deficiency type B | Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg | involves: C57BL/6NTac | J:242197 | View | ||||
| pseudohypoparathyroidism | Del(2Nespas-Gnas)1Hju/+ | either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J) | J:160293 | View | ||||
| pseudohypoparathyroidism |
Gnastm5.1Lsw/Gnastm5.1Lsw Tg(Slc5a2-cre)1Tauc/0 |
involves: C57BL/6 * DBA/2 | J:233851 | View | ||||
| pseudopseudohypoparathyroidism | Gnastm1Gwa/Gnas+ | involves: 129S/SvEv * 129S4/SvJae | J:174525 | View | ||||
| renal hypomagnesemia 3 | Cldn16tm1.1Dmu/Cldn16tm1.1Dmu | involves: 129 * BALB/cJ * C57BL/6 | J:159706 | View | ||||
| renal hypomagnesemia 3 | Tg(RNU6-RNAi:Cldn16)551Dago/0 | involves: C57BL/6 * DBA/2 | J:122766 | View | ||||
| Wilson disease | Atp7btm1Tcg/Atp7btm1Tcg | involves: 129S1/Sv | J:57632 | View | ||||
| Wilson disease | Atp7btx-J/Atp7btx-J | C3H/HeJ-Atp7btx-J/J | J:130273 | View | ||||
| Wilson disease | Atp7btx/Atp7btx | DL-Atp7btx | J:35781 | View | ||||
| | Albright's hereditary osteodystrophy | Pthlhtm1Hmk/Pthlhtm1Hmk | either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) | J:16911 | View | |||
| hemochromatosis | B2mtm1Jae/B2mtm1Jae | involves: 129S2/SvPas | J:17527 | View | ||||
| hemochromatosis | Hmox1tm1Poss/Hmox1tm1Poss | involves: 129S2/SvPas * C57BL/6 | J:79254 | View | ||||
| hypokalemic periodic paralysis | Scn4atm1.1Cann/Scn4atm1.1Cann | involves: 129 | J:178228 | View | ||||
| pseudohypoparathyroidism | Gnasas1tm1.1Hju/Gnasas1+ | either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J) | J:160293 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | hemochromatosis type 1 |
Hfetm1Wsr/Hfetm1Wsr Tg(Vil1-cre)997Gum/? |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:141745 | View | |||
| hemochromatosis type 4 | Slc40a1tm1Nca/Slc40a1+ | involves: 129S4/SvJae * 129S6/SvEvTac | J:129846 | View | ||||