Phenotypes Associated with This Genotype

Genotype
MGI:3033469

• Allelic Composition: Hfe^tm3Sly/Hfe^tm3Sly
• Genetic Background: involves: 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased liver iron level ( J:88143 )

• increased hepatic iron concentrations in both males and females

• increased relative to Hfe^tm2Sly (H67D)

• iron has a predominantly periportal distribution

liver/biliary system

increased liver iron level ( J:88143 )

• increased hepatic iron concentrations in both males and females

• increased relative to Hfe^tm2Sly (H67D)

• iron has a predominantly periportal distribution

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hemochromatosis type 1		DOID:0111029	OMIM:235200	J:88143