About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3576233
Allelic
Composition
B2mtm1Jae/B2mtm1Jae
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Jae mutation (8 available); any B2m mutation (122 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• abnormal deposits of ferric iron in liver and increased total hepatic iron levels (1583 ug/g dry tissue vs. 468 ug/g in wildtype)
• occasionally saw deposits of ferric iron in myocytes, in the branchial wall and lumen of the lung, in the pancreas, and in 5 week old marginal zone of the spleen

hematopoietic system

immune system

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hemochromatosis DOID:2352 OMIM:231100
OMIM:PS235200
J:17527


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory