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Ssbp3 Gene Detail
Summary
  • Symbol
    Ssbp3
  • Name
    single-stranded DNA binding protein 3
  • Synonyms
    2610021L12Rik, 2610200M23Rik, 5730488C10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919725
    NCBI Gene: 72475
  • Alliance
    genome feature page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106768667-106906891 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 49.90 cM, cytoband C7
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2951 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919725
 protein coding gene Chr4:106767898-106906891 (+)
129S1/SvImJ ENSMUSG00200045666
 protein coding gene Chr4:101826818-101966325 (+)
A/J ENSMUSG00195041230
 protein coding gene Chr4:102369631-102509170 (+)
AKR/J ENSMUSG00220006037
 protein coding gene Chr4:101777999-101917515 (+)
BALB/cJ ENSMUSG00180031039
 protein coding gene Chr4:101212843-101352392 (+)
C3H/HeJ ENSMUSG00175014774
 protein coding gene Chr4:102217354-102356881 (+)
C57BL/6NJ ENSMUSG00215024385
 protein coding gene Chr4:102099923-102239257 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026241
 protein coding gene Chr4:98995550-99134029 (+)
CAST/EiJ ENSTCUG00005007073
 protein coding gene Chr4:101319326-101457928 (+)
CBA/J ENSMUSG00210053102
 protein coding gene Chr4:101850353-101989894 (+)
DBA/2J ENSMUSG00185044097
 protein coding gene Chr4:102546422-102685885 (+)
FVB/NJ ENSMUSG00205014937
 protein coding gene Chr4:100781325-100920848 (+)
JF1/MsJ ENSUMUG00000021136
 protein coding gene Chr4:102563679-102703305 (+)
LP/J ENSMUSG00230008898
 protein coding gene Chr4:105863279-106002785 (+)
NOD/ShiLtJ ENSMUSG00190042934
 protein coding gene Chr4:101220182-101359703 (+)
NZO/HlLtJ ENSMUSG00225032462
 protein coding gene Chr4:110965021-111104479 (+)
PWK/PhJ ENSLUMG00010017575
 protein coding gene Chr4:100283214-100421737 (+)
SPRET/EiJ ENSMSPG00010026372
 protein coding gene Chr4:102531788-102670595 (+)
WSB/EiJ ENSIUOG00005002962
 protein coding gene Chr4:101428383-101567878 (+)



Homology
more
  • Human Ortholog
    SSBP3, single stranded DNA binding protein 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SSBP3, single stranded DNA binding protein 3
  • Synonyms
    CSDP, SSDP, SSDP1
  • Links
    NCBI Gene ID: 23648
    UniProt: Q9BWW4

  • Chr Location
    1p32.3; chr1:54225432-54413490 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 2 alleles in 1 genetic background
    31 phenotypes from multigenic genotypes
    1 images
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Embryos homozygous for a gene trap mutation that deletes the proline-rich domain show a severe anterior truncation and a lethal headless phenotype (loss of fore- and midbrain). Embryos homozygous for a gene trap mutation which retains most of the proline-rich domain show normal head development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    659
  • Tissues
    40
  • cDNA Data
    19
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72475 NCBI Gene Model | MGI Sequence Detail 138225 C57BL/6J ±  kb
    transcript NM_023672 RefSeq | MGI Sequence Detail 3211 C57BL/6  
    polypeptide Q9D032 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 19
      Primer pair 1
      Other 1
      Antibodies 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1917840, MGI:1919697, MGI:2140399, MGI:2140595
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 9
      Gene Ontology 8
      Phenotypes 15
    • Earliest
      J:47326 Bayarsaihan D, et al., Cloning and characterization of a novel sequence-specific single-stranded-DNA-binding protein. Biochem J. 1998 Apr 15;331(Pt 2):447-52
    • Latest
      J:339475 Toren E, et al., The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity. Mol Metab. 2023 Aug 1;76:101785
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory