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Informative Gene Names Initiative
The Mouse Genome Nomenclature group is evaluating gene names and symbols for mouse protein coding genes with gene model nomenclature to make them more informative. New names and symbols are based on annotations of protein domains from InterPro. Name changes are coordinated with the Human Gene Nomenclature Committee, Rat Genome Database and with the GenCode mouse genome annotation team. Contact nomen@jax.org with suggestions or comments regarding the new names.

Completed Genes

What's new in mouse gene nomenclature?

Histone genes have been renamed at the request of histone researchers. We renamed the genes where the histone experts agree that mouse and human genes are orthologous (experts such as Paul Talbert and David Landsman; a paper will be published in the near future). This resulted in the streamlining of histone nomenclature. For example, Hist1h2aa has become H2ac1 in parallel to its human ortholog H2AC1; H2afy is now Macroh2a1, human is MACROH2A1, in keeping with the wishes of histone researchers.

MGI IDOld SymbolNew Symbol  New NameDate Updated
MGI:1931523  Hist1h1aH1f1H1.1 linker histone, cluster member March 17, 2020
MGI:1931526Hist1h1cH1f2H1.2 linker histone, cluster memberMarch 17, 2020
MGI:107502Hist1h1dH1f3H1.3 linker histone, cluster memberMarch 17, 2020
MGI:1931527Hist1h1eH1f4H1.4 linker histone, cluster memberMarch 17, 2020
MGI:1861461Hist1h1bH1f5H1.5 linker histone, cluster memberMarch 17, 2020
MGI:1888530Hist1h1tH1f6H1.6 linker histone, cluster memberMarch 17, 2020
MGI:1917319H1fntH1f7H1.7 linker histoneMarch 17, 2020
MGI:2176207H1fooH1f8H1.8 linker histoneMarch 17, 2020
MGI:2685307H1fxH1f10H1.10 linker histoneMarch 17, 2020
MGI:3645322Gm6970H1f11-psH1.11 linker histone, pseudogeneMarch 17, 2020
MGI:3642445H2afb1H2ab1H2A.B variant histone 1March 17, 2020
MGI:3644980H2afb2H2ab2H2A.B variant histone 2March 17, 2020
MGI:3644875H2afb3H2ab3H2A.B variant histone 3March 17, 2020
MGI:1349392H2afyMacroh2a1macroH2A.1 histoneMarch 17, 2020
MGI:3037658H2afy2Macroh2a2macroH2A.2 histoneMarch 17, 2020
MGI:1914802H2afy3Macroh2a3macroH2A.3 histoneMarch 17, 2020
MGI:102688H2afxH2axH2A.X variant histoneMarch 17, 2020
MGI:1888388H2afzH2az1H2A.Z variant histone 1March 17, 2020
MGI:2448285Hist1h2aaH2ac1H2A clustered histone 1March 17, 2020
MGI:2448306Hist1h2abH2ac4H2A clustered histone 4March 17, 2020
MGI:3651860Gm11336H2ac5-psH2A clustered histone 5, pseudogene  March 17, 2020
MGI:2448287Hist1h2acH2ac6H2A clustered histone 6March 17, 2020
MGI:2448289Hist1h2adH2ac7H2A clustered histone 7March 17, 2020
MGI:2448290Hist1h2aeH2ac8H2A clustered histone 8March 17, 2020
MGI:2448309Hist1h2afH2ac10H2A clustered histone 10March 17, 2020
MGI:2448293Hist1h2agH2ac11H2A clustered histone 11March 17, 2020
MGI:2448295Hist1h2ahH2ac12H2A clustered histone 12March 17, 2020
MGI:2448457Hist1h2aiH2ac13H2A clustered histone 13March 17, 2020
MGI:2448312Hist1h2ajH2ac14H2A clustered histone 14March 17, 2020
MGI:2448297Hist1h2akH2ac15H2A clustered histone 15March 17, 2020
MGI:96097Hist2h2aa1H2ac18H2A clustered histone 18March 17, 2020
MGI:2448283Hist2h2aa2H2ac19H2A clustered histone 19March 17, 2020
MGI:2448316Hist2h2acH2ac20H2A clustered histone 20March 17, 2020
MGI:2448314Hist2h2abH2ac21H2A clustered histone 21March 17, 2020
MGI:2448375Hist1h2baH2bc1H2B clustered histone 1March 17, 2020
MGI:2448377Hist1b2bbH2bc3H2B clustered histone 3March 17, 2020
MGI:1915274Hist1h2bcH2bc4H2B clustered histone 4March 17, 2020
MGI:2448380Hist1h2beH2bc6H2B clustered histone 6March 17, 2020
MGI:2448383Hist1h2bfH2bc7H2B clustered histone 7March 17, 2020
MGI:2448386Hist1h2bgH2bc8H2B clustered histone 8March 17, 2020
MGI:2448387Hist1h2bhH2bc9H2B clustered histone 9March 17, 2020
MGI:2448388Hist1h2bjH2bc11H2B clustered histone 11March 17, 2020
MGI:2448399Hist1h2bkH2bc12H2B clustered histone 12March 17, 2020
MGI:2448403Hist1h2blH2bc13H2B clustered histone 13March 17, 2020
MGI:2448404Hist1h2bmH2bc14H2B clustered histone 14March 17, 2020
MGI:2448407Hist1h2bnH2bc15H2B clustered histone 15March 17, 2020
MGI:2448413Hist1h2bbH2bc18H2B clustered histone 18March 17, 2020
MGI:2448415Hist2h2beH2bc21H2B clustered histone 21March 17, 2020
MGI:1925553Hist3h2baH2bu2H2B.U histone 2March 17, 2020
MGI:1922442Hist3h2bb-psH2bu1-psH2B.U histone 1, pseudogeneMarch 17, 2020
MGI:2668828Hist1h3aH3c1H3 clustered histone 1March 17, 2020
MGI:2448319Hist1h3bH3c2H3 clustered histone 2March 17, 2020
MGI:2448320Hist1h3cH3c3H3 clustered histone 3March 17, 2020
MGI:2448322Hist1h3dH3c4H3 clustered histone 4March 17, 2020
MGI:2448326Hist1h3eH3c6H3 clustered histone 6March 17, 2020
MGI:2448329Hist1h3fH3c7H3 clustered histone 7March 17, 2020
MGI:2145541Hist1h3gH3c8H3 clustered histone 8March 17, 2020
MGI:2448349Hist1h3hH3c10H3 clustered histone 10March 17, 2020
MGI:2448350Hist1h3iH3c11H3 clustered histone 11March 17, 2020
MGI:2448351Hist2h3bH3c13H3 clustered histone 13March 17, 2020
MGI:2448355Hist2h3c1H3c14H3 clustered histone 14March 17, 2020
MGI:2448357Hist2h3c2H3c15H3 clustered histone 15March 17, 2020
MGI:2448419Hist1h4aH4c1H4 clustered histone 1March 17, 2020
MGI:2448420Hist1h4bH4c2H4 clustered histone 2March 17, 2020
MGI:2448421Hist1h4cH4c3H4 clustered histone 3March 17, 2020
MGI:2448423Hist1h4dH4c4H4 clustered histone 4March 17, 2020
MGI:2448425Hist1h4fH4c6H4 clustered histone 6March 17, 2020
MGI:2448427Hist1h4hH4c8H4 clustered histone 8March 17, 2020
MGI:2448432Hist1h4iH4c9H4 clustered histone 9March 17, 2020

 

Previous Updates:
MGI IDOld SymbolNew Symbol  New NameDate Updated
MGI:1914825  4930430A15RikA26c3ANKRD26-like family C, member 319 September, 2019
MGI:3028051C130079G13Rik  Aadacl2fm1  AADACL2 family member 119 September, 2019
MGI:3779495Gm5538Aadacl2fm2  AADACL2 family member 219 September, 2019
MGI:3643798Gm8298Aadacl2fm3AADACL2 family member 319 September, 2019
MGI:26858809430007A20RikAadacl4fm1AADACL4 family member 119 September, 2019
MGI:3652194Gm13124Aadacl4fm2AADACL4 family member 219 September, 2019
MGI:3650721Gm13178Aadacl4fm3AADACL4 family member 319 September, 2019
MGI:2685282Gm436Aadacl4fm4AADACL4 family member 419 September, 2019
MGI:2685284Gm438Aadacl4fm5AADACL4 family member 519 September, 2019
MGI:19258751700061G19RikAcsbg3acyl-CoA synthetase bubblegum family member 319 September, 2019
MGI:19233425830473C10RikAlbfm1albumin superfamily member 119 September, 2019
MGI:30453474933408B17RikBrd8dcBRD8 domain containing19 September, 2019
MGI:19186455430419D17RikCdcp3CUB domain containing protein 319 September, 2019
MGI:26859204922502D21RikClec2mC-type lectin domain family 2, member m19 September, 2019
MGI:3644285Gm6880Ctag2l1CTAG2 like 119 September, 2019
MGI:3645826Gm6890Ctag2l2CTAG2 like 219 September, 2019
MGI:3709605Gm14851Defa38defensin, alpha, 3819 September, 2019
MGI:3708769Gm15292Defa40defensin, alpha, 4019 September, 2019
MGI:3705230Gm15293Defa41defensin, alpha, 4119 September, 2019
MGI:3645033Gm7849Defa42defensin, alpha, 4219 September, 2019
MGI:3648003Gm7861Defa43defensin, alpha, 4319 September, 2019
MGI:19170111600015I10RikDoxl1diamine oxidase-like protein 119 September, 2019
MGI:19261461500015O10RikEcrg4ECRG4 augurin precursor19 September, 2019
MGI:19166911700023F06RikEfcab15EF-hand calcium binding domain 1519 September, 2019
MGI:3644226Gm8994Eif4a3l1eukaryotic translation initiation factor 4A3 like 119 September, 2019
MGI:26870414833423E24RikFads2bfatty acid desaturase 2B19 September, 2019
MGI:37143511700047I17Rik2Fam177a2family with sequence similarity 177 member A219 September, 2019
MGI:24416894931440F15RikFem1alfem-1 homolog A like19 September, 2019
MGI:2685441Gm595Fsip2lpredicted gene 595fibrous sheath-interacting protein 2-like19 September, 2019
MGI:3045360E330017A01RikFtdcferritin domain containing19 September, 2019
MGI:2685002Gm156Klrh1killer cell lectin-like receptor subfamily H, member 119 September, 2019
MGI:19173842210011C24RikMisp3MISP family member 319 September, 2019
MGI:19140134933425L06RikNt5el5' nucleotidase, ecto-like19 September, 2019
MGI:3710598Gm13769Olfr1565olfactory receptor 156519 September, 2019
MGI:19140054933415F23RikPpp1r14blprotein phosphatase 1, regulatory inhibitor subunit 14B like19 September, 2019
MGI:2441881C130060K24RikQrfprlpyroglutamylated RFamide peptide receptor like19 September, 2019
MGI:26849739130204L05RikS100a7l2S100 calcium binding protein A7 like 219 September, 2019
MGI:19253424921511M17RikSamt1bspermatogenesis associated multipass transmembrane protein 1b19 September, 2019
MGI:3710528Gm10057Samt1cspermatogenesis associated multipass transmembrane protein 1c19 September, 2019
MGI:3709336Gm15140Samt1dspermatogenesis associated multipass transmembrane protein 1d19 September, 2019
MGI:19223214930524N10RikSamt2bspermatogenesis associated multipass transmembrane protein 2b19 September, 2019
MGI:2441788A230050P20RikShflshiftless antiviral inhibitor of ribosomal frameshifting19 September, 2019
MGI:3645333Gm5868Slc10a4l solute carrier family 10 (sodium/bile acid cotransporter family), member 4 like    19 September, 2019
MGI:3702173Gm14085Slc28a2bsolute carrier family 28 member 2b19 September, 2019
MGI:26859396430531B16RikSpef1lsperm flagellar 1 like19 September, 2019
MGI:19139824921530L21RikSpertlspermatid associated like19 September, 2019
MGI:3702972Gm10696Spopfm2speckle-type BTB/POZ protein family member 219 September, 2019
MGI:3645677Gm4858Tdpoz8TD and POZ domain containing 819 September, 2019
MGI:3702970Gm9125Tdpoz9TD and POZ domain containing 919 September, 2019
MGI:3702974Gm7534Zpld2zona pellucida like domain containing 219 September, 2019

In Progress

The table below lists a subset of the genes we are currently working on. This subset lists unnamed members of the PRAME gene family.
Current SymbolCurrent NameUniProt ID  UniProt Name
A430089I19Rik  RIKEN cDNA A430089I19 gene  IPR026271PRAME family
B020004J07RikRIKEN cDNA B020004J07 geneIPR026271PRAME family
Gm10424  predicted gene 10424  IPR026271   PRAME family  
Gm10436predicted gene 10436IPR026271 PRAME family  
Gm12794predicted gene 12794IPR026271PRAME family
Gm12800predicted gene 12800IPR026271PRAME family
Gm13023predicted gene 13023IPR026271PRAME family
Gm13078predicted gene 13078IPR026271PRAME family
Gm13083predicted gene 13083IPR026271PRAME family
Gm13084predicted gene 13084IPR026271PRAME family
Gm13088predicted gene 13088IPR026271PRAME family
Gm13089predicted gene 13089IPR026271PRAME family
Gm13101predicted gene 13101IPR026271PRAME family
Gm13103predicted gene 13103IPR026271PRAME family
Gm13119predicted gene 13119IPR026271PRAME family
Gm13128predicted gene 13128IPR026271PRAME family
Gm16367predicted gene 16367IPR026271PRAME family
Gm16427predicted gene 16427IPR026271PRAME family
Gm16429predicted gene 16429IPR026271PRAME family
Gm3106predicted gene 3106IPR026271PRAME family
Gm3139predicted gene 3139IPR026271PRAME family
Gm3147predicted gene 3147IPR026271PRAME family
Gm3259predicted gene 3259IPR026271PRAME family
Gm6502predicted gene 6502IPR026271PRAME family
Gm6509predicted gene 6509IPR026271PRAME family
Gm7682predicted gene 7682IPR026271PRAME family
Gm7792predicted gene 7792IPR026271PRAME family
Gm7942predicted gene 7942IPR026271PRAME family
Gm7971predicted gene 7971IPR026271PRAME family
Gm7978predicted gene 7978IPR026271PRAME family

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory