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H3c2 Gene Detail
Summary
  • Symbol
    H3c2
  • Name
    H3 clustered histone 2
  • Synonyms
    H3-53, Hist1h3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448319
    NCBI Gene: 319150
  • Member of
    Hist1 cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23936328-23936823 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448319
 protein coding gene Chr13:23936250-23936869 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018335
 protein coding gene Chr13:19579983-19580521 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010029052
 protein coding gene Chr13:19873132-19873750 (+)
SPRET/EiJ ENSMSPG00010018147
 protein coding gene Chr13:19650179-19650798 (+)
WSB/EiJ ENSIUOG00005032281
 protein coding gene Chr13:19837899-19838518 (+)



Homology
more
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Vertebrate Orthologs
    11
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Synonyms
    HIST2H3D
  • Links
    NCBI Gene ID: 653604
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149813225-149813693 (-)  GRCh38
  • Human Ortholog
    H3C14, H3 clustered histone 14
  • Synonyms
    H3, H3.2, H3F2, H3FM, H3FN, H3/M, HIST2H3C
  • Links
    NCBI Gene ID: 126961
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149840687-149841208 (-)  GRCh38
  • Human Ortholog
    H3C15, H3 clustered histone 15
  • Synonyms
    H3/n, H3/o, HIST2H3A
  • Links
    NCBI Gene ID: 333932
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149852608-149853125 (+)  GRCh38
  • Human Ortholog
    H3C2, H3 clustered histone 2
  • Synonyms
    H3FL, H3/l, HIST1H3B
  • Links
    NCBI Gene ID: 8358
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26031589-26032099 (-)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    620
  • Tissues
    21
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319150 NCBI Gene Model | MGI Sequence Detail 496 C57BL/6J ±  kb
transcript NM_178203 RefSeq | MGI Sequence Detail 496 C57BL/6  
polypeptide P84228 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 3
    Genomic 1
    Primer pair 2
Other
Accession IDs
less
MGI:6324965
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Diseases 1
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:332290 Vetrivel S, et al., Identification of ocular regulatory functions of core histone variant H3.2. Exp Eye Res. 2022 Dec 15;226:109346
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory