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H4c8 Gene Detail
Summary
  • Symbol
    H4c8
  • Name
    H4 clustered histone 8
  • Synonyms
    Hist1h4h
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448427
    NCBI Gene: 69386
  • Member of
    Hist1 cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23715214-23715648 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.77 cM, cytoband A2-A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448427
protein coding gene Chr13:23715214-23715689 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018316
protein coding gene Chr13:19372753-19373225 (+)
CAST/EiJ ENSTCUG00005009964
protein coding gene Chr13:20498410-20498879 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000010105
protein coding gene Chr13:20761473-20761944 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010026331
protein coding gene Chr13:19660157-19660628 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005031828
protein coding gene Chr13:19612196-19612665 (+)



Homology
more
  • Human Ortholog
    H4C1, H4 clustered histone 1
  • Vertebrate Orthologs
    31
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H4C1, H4 clustered histone 1
  • Synonyms
    H4FA, HIST1H4A
  • Links
    NCBI Gene ID: 8359
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26021649-26022847 (+)  GRCh38

  • Human Ortholog
    H4C11, H4 clustered histone 11
  • Synonyms
    dJ160A22.2, H4/e, H4F2iv, H4FE, HIST1H4J, TEBIVANED2, TEVANED2
  • Links
    NCBI Gene ID: 8363
    UniProt: P62805

  • Chr Location
    6p22.1; chr6:27824092-27824480 (+)  GRCh38

  • Human Ortholog
    H4C12, H4 clustered histone 12
  • Synonyms
    dJ160A22.1, H4/d, H4F2iii, H4FD, HIST1H4K
  • Links
    NCBI Gene ID: 8362
    UniProt: P62805

  • Chr Location
    6p22.1; chr6:27830918-27831560 (-)  GRCh38

  • Human Ortholog
    H4C13, H4 clustered histone 13
  • Synonyms
    H4FK, H4.k, H4/k, HIST1H4L
  • Links
    NCBI Gene ID: 8368
    UniProt: P62805

  • Chr Location
    6p22.1; chr6:27873148-27873534 (-)  GRCh38

  • Human Ortholog
    H4C14, H4 clustered histone 14
  • Synonyms
    FO108, H4, H4F2, H4FN, H4/n, HIST2H4, HIST2H4A
  • Links
    NCBI Gene ID: 8370
    UniProt: P62805

  • Chr Location
    1q21.2; chr1:149832657-149839767 (+)  GRCh38

  • Human Ortholog
    H4C15, H4 clustered histone 15
  • Synonyms
    H4/o, HIST2H4B
  • Links
    NCBI Gene ID: 554313
    UniProt: P62805

  • Chr Location
    1q21.2; chr1:149844488-149861240 (-)  GRCh38

  • Human Ortholog
    H4C16, H4 histone 16
  • Synonyms
    H4-16, H4/p, HIST4H4
  • Links
    NCBI Gene ID: 121504
    UniProt: P62805

  • Chr Location
    12p12.3; chr12:14767999-14771131 (-)  GRCh38

  • Human Ortholog
    H4C2, H4 clustered histone 2
  • Synonyms
    H4FI, H4/I, HIST1H4B
  • Links
    NCBI Gene ID: 8366
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26025802-26027283 (-)  GRCh38

  • Human Ortholog
    H4C3, H4 clustered histone 3
  • Synonyms
    dJ221C16.1, H4FG, H4/g, HIST1H4C, TEBIVANED1, TEVANED1
  • Links
    NCBI Gene ID: 8364
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26103933-26104337 (+)  GRCh38

  • Human Ortholog
    H4C4, H4 clustered histone 4
  • Synonyms
    dJ221C16.9, H4/b, H4FB, HIST1H4D
  • Links
    NCBI Gene ID: 8360
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26188710-26189112 (-)  GRCh38

  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Synonyms
    H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
  • Links
    NCBI Gene ID: 8367
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26204610-26205021 (+)  GRCh38

  • Human Ortholog
    H4C6, H4 clustered histone 6
  • Synonyms
    H4, H4/c, H4FC, HIST1H4F
  • Links
    NCBI Gene ID: 8361
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26240393-26240793 (+)  GRCh38

  • Human Ortholog
    H4C8, H4 clustered histone 8
  • Synonyms
    H4FH, H4/h, HIST1H4H
  • Links
    NCBI Gene ID: 8365
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26277609-26285638 (-)  GRCh38

  • Human Ortholog
    H4C9, H4 clustered histone 9
  • Synonyms
    H4FM, H4/m, H4M, HIST1H4I, TEBIVANED4, TEVANED4
  • Links
    NCBI Gene ID: 8294
    UniProt: P62805

  • Chr Location
    6p22.1; chr6:27139282-27140640 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H4c8
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69386 NCBI Gene Model | MGI Sequence Detail 435 C57BL/6J ±  kb
transcript NM_153173 RefSeq | MGI Sequence Detail 435 C57BL/6  
polypeptide P62806 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916636, MGI:6324989
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:320332 Kujirai T, et al., Transcription through the nucleosome. Curr Opin Struct Biol. 2020 Apr;61:42-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory