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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prdm1
PR domain containing 1, with ZNF domain
MGI:99655
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Clptm1ltm1d(EUCOMM)Wtsi/Clptm1ltm1d(EUCOMM)Wtsi
Prdm1tm1Nutt/Prdm1+
involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N 		normal immune system phenotype J:265892
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+
Prdm1tm2Masu/Prdm1tm2Masu
involves: 129P2/OlaHsd * 129X1/SvJ 		abnormal germinal center B cell physiology J:167612
abnormal plasma cell differentiation J:167612
decreased IgG1 level J:167612
decreased survivor rate J:167612
enlarged liver J:167612
enlarged lymph nodes J:167612
enlarged spleen J:167612
increased B cell derived lymphoma incidence J:167612
increased germinal center B cell number J:167612
premature death J:167612
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+
Prdm1tm2Masu/Prdm1tm2Masu
involves: 129P2/OlaHsd * C57BL/6 		abnormal germinal center B cell physiology J:167612
abnormal plasma cell differentiation J:167612
decreased IgG1 level J:167612
decreased survivor rate J:167612
increased B cell derived lymphoma incidence J:167612
increased germinal center B cell number J:167612
premature death J:167612
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Krastm4Tyj/Kras+
Prdm1tm1Clme/Prdm1tm1Clme
Tg(Pdx1-cre)6Tuv/0
Trp53tm2Tyj/Trp53+
involves: 129 * C57BL/6NCrl * FVB/N 		increased pancreatic ductal adenocarcinoma incidence J:245611
increased pancreatic intraepithelial neoplasia incidence J:245611
premature death J:245611
Il6tm1Kopf/Il6+
Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA 		normal immune system phenotype J:178876
Itm2cem1Nutt/Itm2cem1Nutt
Prdm1tm1Nutt/Prdm1+
involves: C57BL/6 * C57BL/6J 		normal immune system phenotype J:265892
Kdrtm1Jrt/Kdr+
Prdm1tm2Rob/Prdm1tm2Rob
involves: 129 		abnormal placental labyrinth vasculature morphology J:187742
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+
involves: C57BL/6 * C57BL/6N 		normal immune system phenotype J:265892
Prdm1tm3.1Liz/Prdm1tm3.1Liz
involves: 129S/SvEv 		abnormal embryo development J:196531
abnormal placenta morphology J:196531
embryonic growth retardation J:196531
embryonic lethality during organogenesis, complete penetrance J:196531
normal hematopoietic system phenotype J:196531
normal immune system phenotype J:196531
Prdm1tm4.1Liz/Prdm1tm4.1Liz
involves: 129S/SvEv 		no abnormal phenotype detected J:196531
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory