104 phenotypes from 14 alleles in 17 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
En1em1Smun/En1em1Smun involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1	abnormal rib morphology	J:306235
	decreased sternebra size	J:306235
	polydactyly	J:306235
	short sternum	J:306235
	syndactyly	J:306235
En1tm1(Otx2)Wrst/En1+ either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal brain commissure morphology	J:57538
	abnormal brain morphology	J:57538
	abnormal cerebellar lobule formation	J:57538
	abnormal cerebellum morphology	J:57538
	abnormal cerebellum vermis morphology	J:57538
	abnormal corpora quadrigemina morphology	J:57538
	abnormal gait	J:57538
	abnormal locomotor coordination	J:57538
	absent cerebellar lobules	J:57538
	ataxia	J:57538
	decreased anterior vermis size	J:57538
	impaired coordination	J:57538
	increased inferior colliculus size	J:57538
	increased superior colliculus size	J:57538
En1tm1(Otx2)Wrst/En1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	abnormal neuron morphology	J:88192
	abnormal serotonergic neuron morphology	J:88192
	decreased serotonin level	J:88192
	ectopic dopaminergic neuron	J:88192
	increased dopamine level	J:88192
	increased locomotor activity	J:88192
En1tm1(PDGFB)Nist/En1+ involves: 129/Sv * C57BL/6	abnormal brain vasculature morphology	J:90898
	abnormal cell migration	J:90898
	abnormal cerebellum development	J:90898
	normal behavior/neurological phenotype	J:90898
En1tm1(PDGFB)Nist/En1tm1(PDGFB)Nist involves: 129/Sv * C57BL/6	neonatal lethality, complete penetrance	J:90898
En1tm1(Tnf)Fpit/En1tm1(Tnf)Fpit involves: C57BL/6	decreased physiological sensitivity to xenobiotic	J:170743
	normal nervous system phenotype	J:170743
En1tm1(Tnf)Fpit/En1tm1(Tnf)Fpit involves: C57BL/6	abnormal dopaminergic neuron morphology	J:170743
	astrocytosis	J:170743
	decreased neuron number	J:170743
	increased monocyte cell number	J:170743
	microgliosis	J:170743
	neuron degeneration	J:170743
En1tm1(Wnt1)Wrst/En1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cell cycle	J:91004
	abnormal cerebellum morphology	J:91004
	abnormal hindbrain morphology	J:91004
	increased cell proliferation	J:91004
	increased inferior colliculus size	J:91004
En1tm1(Wnt1)Wrst/En1tm1(Wnt1)Wrst involves: 129S1/Sv * 129X1/SvJ * C57BL/6	increased inferior colliculus size	J:91004
	neonatal lethality, complete penetrance	J:91004
En1tm1Alj/En1tm1Alj B6.129-En1tm1Alj	abnormal autopod morphology	J:84363
	abnormal cerebellar lobule formation	J:84363
	abnormal digit morphology	J:84363
	decreased body size	J:84363
	decreased inferior colliculus size	J:84363
	deformed nails	J:84363
	polydactyly	J:84363
	postnatal lethality, incomplete penetrance	J:84363
	syndactyly	J:84363
En1tm1Alj/En1tm1Alj either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal autopod morphology	J:34307
	abnormal axial skeleton morphology	J:19212
	abnormal brain development	J:19212
	abnormal brain morphology	J:19212
	abnormal cerebellum morphology	J:19212
	abnormal choroid plexus morphology	J:19212
	abnormal cranial nerve morphology	J:19212
	abnormal digit morphology	J:19212, J:34307
	abnormal eccrine sweat gland morphology	J:34307
	abnormal foot pad morphology	J:34307
	abnormal hair follicle dermal papilla morphology	J:34307
	abnormal hair follicle development	J:34307
	abnormal limb morphology	J:34307
	abnormal midbrain development	J:19212
	abnormal nail morphology	J:34307
	abnormal suckling behavior	J:19212
	absent cerebellum	J:19212
	absent oculomotor nerve	J:19212
	absent trochlear nerve	J:19212
	aphagia	J:19212
	decreased inferior colliculus size	J:19212
	decreased rib number	J:19212
	delayed bone ossification	J:19212
	ectopic digits	J:34307
	neonatal lethality, complete penetrance	J:19212
	polydactyly	J:19212
	short sternum	J:19212
	syndactyly	J:19212
	thin apical ectodermal ridge	J:34307
	truncated digits	J:19212
	wrinkled skin	J:19212
En1tm1Alj/En1tm1Alj involves: 129 * C57BL/6J	abnormal apical ectodermal ridge morphology	J:45301
En1tm1Alj/En1tm3(En2)Alj either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	no abnormal phenotype detected	J:27767
En1tm1Gld/En1tm1Gld involves: 129S/SvEv	abnormal CNS synaptic transmission	J:106437
En1tm1Gld/En1tm1Gld involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster	decreased dopaminergic neuron number	J:115270
	perinatal lethality, complete penetrance	J:115270
En1tm1Gld/En1tm1Gld involves: 129S/SvEv * C57BL/6	abnormal axon guidance	J:52637
	abnormal innervation	J:52637
	abnormal limb morphology	J:52637
	abnormal neuron differentiation	J:52637
	decreased midbrain size	J:52637
En1tm2(cre)Gld/En1tm2(cre)Gld involves: 129S1/Sv	abnormal synapse morphology	J:87771
	perinatal lethality, incomplete penetrance	J:87771
En1tm2(cre)Wrst/En1tm8.1Alj involves: 129/Sv * Black Swiss * C57BL/6 * SJL	abnormal cerebellum anterior vermis morphology	J:134516
	abnormal inferior colliculus morphology	J:134516
	decreased anterior vermis size	J:134516
En1tm2Alj/En1+ involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	normal nervous system phenotype	J:134516
En1tm2Alj/En1+ Tg(Th-EGFP)6-7Okn/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1	abnormal autophagy	J:214073
	abnormal synaptic dopamine release	J:214073
	axon degeneration	J:214073
	axonal dystrophy	J:214073
	axonal spheroids	J:214073
	decreased dopamine level	J:214073
	decreased dopaminergic neuron number	J:214073
	neurodegeneration	J:214073
En1tm2Alj/En1tm2Alj involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	abnormal cerebellum morphology	J:134516
	abnormal cerebellum posterior vermis morphology	J:134516
	absent inferior colliculus	J:134516
	decreased midbrain size	J:134516
	decreased rhombomere 1 size	J:134516
	decreased superior colliculus size	J:134516
En1tm4(en)Alj/En1tm4(en)Alj involves: 129S1/Sv * 129X1/SvJ	abnormal brain morphology	J:50311
	abnormal cerebellum development	J:50311
	abnormal digit morphology	J:50311
	abnormal digit pigmentation	J:50311
	abnormal fertility/fecundity	J:50311
	abnormal sternebra morphology	J:50311
	abnormal sternum ossification	J:50311
	asymmetric sternocostal joints	J:50311
	decreased inferior colliculus size	J:50311
	deformed nails	J:50311
	male infertility	J:50311
	polydactyly	J:50311
	premature death	J:50311
	syndactyly	J:50311
En1tm5(en)Alj/En1tm5(en)Alj involves: 129S1/Sv * 129X1/SvJ	abnormal brain morphology	J:50311
	abnormal cerebellar lobule formation	J:50311
	abnormal digit morphology	J:34307, J:50311
	abnormal digit pigmentation	J:50311
	abnormal eccrine sweat gland morphology	J:34307
	abnormal foot pad morphology	J:34307
	abnormal hair follicle development	J:34307
	abnormal limb bone morphology	J:34307
	abnormal nail morphology	J:34307
	decreased midbrain size	J:50311
	deformed nails	J:50311
	fused phalanges	J:34307
	polydactyly	J:50311
	premature death	J:50311
	normal skeleton phenotype	J:50311
	syndactyly	J:50311
En1tm5(en)Alj/En1tm5(en)Alj involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	normal mortality/aging	J:134516
	normal nervous system phenotype	J:134516