119 phenotypes from 9 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr/Gt(ROSA)26Sor+ involves: C57BL/6	decreased neutrophil cell number	J:202499
Tg(Krt1-15-cre/PGR*)22Cot/0 Wlstm1.1Lan/Wlstm1.1Lan involves: 129S6/SvEvTac * C57BL/6 * SJL	normal integument phenotype	J:204142
Tg(KRT5-rtTA)#Glk/0 Tg(tetO-cre)1Jaw/0 Wlstm1.1Lan/Wlstm1.1Lan involves: 129S6/SvEvTac * C57BL/6 * FVB/N	abnormal epidermal layer morphology	J:204142
	abnormal hair cycle catagen phase	J:204142
	abnormal hair follicle morphology	J:204142
	abnormal keratinocyte morphology	J:204142
	cutaneous mastocytosis	J:204142
Wlsem1Jgg/Wlsem1Jgg involves: C57BL/6J	abnormal dentate gyrus morphology	J:341542
	abnormal nervous system development	J:341542
	abnormal neural tube closure	J:341542
	abnormal neuron differentiation	J:341542
	abnormal tail bud morphology	J:341542
	adactyly	J:341542
	decreased brain size	J:341542
	decreased caudal vertebrae number	J:341542
	decreased neuron number	J:341542
	hydronephrosis	J:341542
	perinatal lethality, complete penetrance	J:341542
Wlsem2Jgg/Wlsem2Jgg involves: C57BL/6J	abnormal dentate gyrus morphology	J:341542
	abnormal nervous system development	J:341542
	abnormal neural tube closure	J:341542
	abnormal neuron differentiation	J:341542
	abnormal tail bud morphology	J:341542
	adactyly	J:341542
	decreased brain size	J:341542
	decreased caudal vertebrae number	J:341542
	decreased neuron number	J:341542
	hydronephrosis	J:341542
	perinatal lethality, complete penetrance	J:341542
WlsGt(RRJ545)Byg/WlsGt(RRJ545)Byg involves: 129P2/OlaHsd	abnormal developmental patterning	J:154679
	abnormal ectoderm development	J:154679
	abnormal endoderm development	J:154679
	abnormal germ layer development	J:154679
	absent mesoderm	J:154679
	embryonic lethality during organogenesis, complete penetrance	J:154679
	failure of primitive streak formation	J:154679
Wlstm1.1Arte/Wlstm1.1Arte Krt14tm1(cre)Wbm/Krt14+ involves: 129P2/OlaHsd * C57BL/6	abnormal adipose tissue physiology	J:202499
	abnormal ear morphology	J:202499
	abnormal eye morphology	J:202499
	abnormal hair growth	J:202499
	abnormal nose morphology	J:202499
	abnormal skin appearance	J:202499
	abnormal skin physiology	J:202499
	abnormal T cell differentiation	J:202499
	abnormal T cell physiology	J:202499
	abnormal T cell subpopulation ratio	J:202499
	cutaneous mastocytosis	J:202499
	decreased body size	J:202499
	decreased body surface temperature	J:202499
	decreased double-positive T cell number	J:202499
	decreased gamma-delta T cell number	J:202499
	decreased hair follicle number	J:202499
	decreased T cell number	J:202499
	decreased thymus weight	J:202499
	epidermal spongiosis	J:202499
	flaky skin	J:202499
	hair follicle degeneration	J:202499
	impaired skin barrier function	J:202499
	increased double-negative T cell number	J:202499
	increased keratinocyte proliferation	J:202499
	increased macrophage cell number	J:202499
	increased neutrophil cell number	J:202499
	increased T cell proliferation	J:202499
	postnatal growth retardation	J:202499
	premature death	J:202499
	reddish skin	J:202499
	scaly skin	J:202499
	skin inflammation	J:202499
	small thymus medulla	J:202499
	sparse hair	J:202499
	thin dermal layer	J:202499
	thin hypodermis	J:202499
	thin skin	J:202499
	thymus atrophy	J:202499
	thymus hypoplasia	J:202499
Wlstm1.1Arte/Wlstm1.1Arte Tg(CMV-cre)1Cgn/? involves: BALB/cJ * C57BL/6	embryonic lethality, complete penetrance	J:202499
Wlstm1.1Arte/Wlstm1.1Arte Tg(Foxn1-cre)1Tbo/0 involves: C57BL/6	normal immune system phenotype	J:202499
	normal integument phenotype	J:202499
	sparse hair	J:202499
Wlstm1.1Lan/Wlstm1.1Lan H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S/SvEv * C57BL/6J * CBA/J * SJL	abnormal metencephalon morphology	J:164701
	abnormal neural tube morphology	J:164701
	absent cerebellum	J:164701
	absent choroid plexus	J:164701
	absent midbrain	J:164701
	absent midbrain-hindbrain boundary	J:164701
	decreased forebrain size	J:164701
	perinatal lethality	J:164701
	short rostral-caudal axis	J:164701
Wlstm1.1Lan/Wlstm1.1Lan Tg(EIIa-cre)C5379Lmgd/0 involves: 129S/SvEv * FVB/N * SJL	embryonic growth arrest	J:164701
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:164701
	failure of primitive streak formation	J:164701
Wlstm1.1Lan/Wlstm1.1Lan Tg(Pdx1-cre)6Tuv/0 involves: 129S/SvEv * FVB/N * SJL	pancreas hypoplasia	J:164701
Wlstm1.1Whsu/Wlstm1.1Whsu H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal brain morphology	J:167835
	abnormal cranial nerve morphology	J:167835
	abnormal craniofacial development	J:167835
	abnormal craniofacial morphology	J:167835
	abnormal hindbrain development	J:167835
	abnormal midbrain development	J:167835
	abnormal midbrain-hindbrain boundary development	J:167835
	abnormal neurocranium morphology	J:167835
	abnormal salivary gland morphology	J:167835
	abnormal serous gland morphology	J:167835
	abnormal tooth morphology	J:167835
	abnormal viscerocranium morphology	J:167835
	absent cerebellum	J:167835
	absent choroid plexus	J:167835
	absent tectum	J:167835
	absent tegmentum	J:167835
	cleft palate	J:167835
Wlstm1.2Whsu/Wlstm1.2Whsu involves: 129S6/SvEvTac	abnormal rostral-caudal axis patterning	J:167835
	absent mesoderm	J:167835
	embryonic growth arrest	J:167835
	embryonic lethality during organogenesis, complete penetrance	J:167835
	failure of primitive streak formation	J:167835
Wlstm1Xzg/Wlstm1Xzg Tg(Msx2-cre)5Rem/0 Not Specified	abnormal apical ectodermal ridge morphology	J:184918
	abnormal dermal layer morphology	J:184918
	abnormal forelimb morphology	J:184918
	abnormal forelimb stylopod morphology	J:184918
	abnormal hair follicle development	J:184918
	abnormal hindlimb morphology	J:184918
	abnormal hindlimb zeugopod morphology	J:184918
	abnormal ligament morphology	J:184918
	abnormal limb development	J:184918
	abnormal muscle development	J:184918
	abnormal tendon morphology	J:184918
	decreased autopod size	J:184918
	decreased cell proliferation	J:184918
	delayed cranial suture closure	J:184918
	increased apoptosis	J:184918
	oligodactyly	J:184918
	short fibula	J:184918
	short limbs	J:184918
	short tibia	J:184918
	thin apical ectodermal ridge	J:184918
Wlstm1Xzg/Wlstm1Xzg Tg(Prrx1-cre)1Cjt/0 involves: C57BL/6J * SJL/J	abnormal digit development	J:184918
	abnormal limb development	J:184918
	abnormal skeleton morphology	J:184918
	adipsia	J:184918
	chondrodystrophy	J:184918
	decreased autopod size	J:184918
	decreased cell proliferation	J:184918
	delayed bone ossification	J:184918
	increased apoptosis	J:184918
	lethality at weaning, incomplete penetrance	J:184918
	short limbs	J:184918