77 phenotypes from 8 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bcl6tm1.1Dent/Bcl6tm1.1Dent involves: 129S/SvEv * C57BL/6 * FVB/N	no abnormal phenotype detected	J:202372
Bcl6tm1.1Dent/Bcl6tm1.1Dent Tg(Cd4-cre)1Cwi/0 involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N	abnormal T follicular helper cell differentiation	J:202372
	decreased germinal center B cell number	J:202372
	decreased IgG level	J:202372
	decreased interleukin-4 secretion	J:202372
	decreased T follicular helper cell number	J:202372
	increased interleukin-10 secretion	J:202372
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Cd79atm1(cre)Reth/Cd79a+ involves: BALB/c * C57BL/6 * C57BL/6JJcl	abnormal humoral immune response	J:190943
	abnormal memory B cell morphology	J:190943
	abnormal memory B cell physiology	J:190943
	abnormal somatic hypermutation frequency	J:190943
	decreased germinal center B cell number	J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Cd79atm1(cre)Reth/Cd79a+ Tg(Cd4-cre)1Cwi/0 involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2	decreased germinal center B cell number	J:190943
	normal immune system phenotype	J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Ighg1tm1(cre)Cgn/Ighg1+ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl	decreased germinal center B cell number	J:190943
	normal immune system phenotype	J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * C57BL/6JJcl * DBA/2	abnormal humoral immune response	J:190943
	abnormal somatic hypermutation frequency	J:190943
	absent germinal center B cells	J:190943
	decreased germinal center B cell number	J:190943
	decreased T follicular helper cell number	J:190943
Bcl6tm1.1Toka/Bcl6tm1.1Toka involves: C57BL/6 * NZB	abnormal Peyer's patch morphology	J:174014
	decreased germinal center B cell number	J:174014
	decreased T follicular helper cell number	J:174014
	normal immune system phenotype	J:174014
Bcl6tm1Gdba/Bcl6tm1Gdba Tg(ACTA1-rtTA,tetO-cre)102Monk/0 involves: C3H * C57BL/6	increased body fat mass	J:271078
	increased white adipose tissue amount	J:271078
	increased white fat cell size	J:271078
Bcl6tm1Gdba/Bcl6tm1Gdba Tg(Adipoq-cre)1Evdr/0 involves: C57BL/6 * FVB/NJ	abnormal gonadal fat pad morphology	J:271078
	abnormal lipid level	J:271078
	decreased adipocyte glucose uptake	J:271078
	decreased ceramide level	J:271078
	decreased circulating free fatty acids level	J:271078
	decreased circulating insulin level	J:271078
	decreased circulating triglyceride level	J:271078
	decreased fasting circulating glucose level	J:271078
	decreased liver triglyceride level	J:271078
	decreased liver weight	J:271078
	decreased respiratory quotient	J:271078
	decreased susceptibility to diet-induced hepatic steatosis	J:271078
	impaired gluconeogenesis	J:271078
	increased adipocyte glucose uptake	J:271078
	increased body fat mass	J:271078
	increased circulating adiponectin level	J:271078
	increased circulating leptin level	J:271078
	increased insulin sensitivity	J:271078
	increased lipogenesis	J:271078
	increased muscle cell glucose uptake	J:271078
	increased subcutaneous adipose tissue amount	J:271078
	increased susceptibility to diet-induced obesity	J:271078
	increased white fat cell size	J:271078
	white adipose tissue inflammation	J:271078
Bcl6tm1Htno/Bcl6+ involves: 129S1/Sv * 129X1/SvJ	abnormal apoptosis	J:82037
Bcl6tm1Htno/Bcl6tm1Htno involves: 129S1/Sv * 129X1/SvJ	decreased fertilization frequency	J:82037
	increased male germ cell apoptosis	J:82037
	oligozoospermia	J:82037
	reduced male fertility	J:82037
Bcl6tm1Htno/Bcl6tm1Htno involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal spleen morphology	J:55952
	cardiac interstitial fibrosis	J:55952
	decreased body size	J:55952
	decreased body weight	J:55952
	dilated heart ventricle	J:55952
	lung inflammation	J:55952
	myocardial fiber degeneration	J:55952
	myocarditis	J:55952
	postnatal lethality, incomplete penetrance	J:55952
	premature death	J:55952
	thin ventricular wall	J:55952
Bcl6tm1Rdf/Bcl6tm1Rdf involves: 129S1/Sv	abnormal B cell physiology	J:40769
	abnormal humoral immune response	J:40769
	abnormal immune system morphology	J:40769
	abnormal immune system physiology	J:40769
	abnormal Peyer's patch germinal center morphology	J:40769
	abnormal T-helper 2 physiology	J:40769
	absent lymph node germinal center	J:40769
	absent spleen germinal center	J:40769
	decreased IgG level	J:40769
	decreased IgM level	J:40769
	heart inflammation	J:40769
	increased eosinophil cell number	J:40769
	increased inflammatory response	J:40769
	increased susceptibility to bacterial infection	J:40769
	liver inflammation	J:40769
	lung inflammation	J:40769
	postnatal growth retardation	J:40769
	small thymus	J:40769
	spleen hyperplasia	J:40769
Bcl6tm1Sdt/Bcl6tm1Sdt involves: 129/Sv * C57BL/6	abnormal blood cell morphology/development	J:123621
	abnormal chemokine level	J:123621
	abnormal immune system physiology	J:123621
	decreased bone marrow cell number	J:123621
	postnatal growth retardation	J:123621
	postnatal lethality, incomplete penetrance	J:123621
	spleen hypoplasia	J:123621
Bcl6tm2Rdf/Bcl6tm2Rdf involves: 129S1/Sv	abnormal B cell physiology	J:40769
	abnormal humoral immune response	J:40769
	abnormal immune system morphology	J:40769
	abnormal immune system physiology	J:40769
	abnormal Peyer's patch germinal center morphology	J:40769
	abnormal T-helper 2 physiology	J:40769
	absent lymph node germinal center	J:40769
	absent spleen germinal center	J:40769
	decreased B cell proliferation	J:40769
	decreased body size	J:194821
	decreased IgG level	J:40769
	decreased IgM level	J:40769
	heart inflammation	J:40769
	increased eosinophil cell number	J:40769
	increased inflammatory response	J:40769
	increased susceptibility to bacterial infection	J:40769
	liver inflammation	J:40769
	lung inflammation	J:40769
	postnatal growth retardation	J:40769
	prenatal lethality, incomplete penetrance	J:194821
	small thymus	J:40769
	spleen hyperplasia	J:40769