Rest Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rest
RE1-silencing transcription factor
MGI:104897

39 phenotypes from 10 alleles in 15 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dct^tm1(cre)Bee/Dct⁺ Rest^tm1.1Yasu/Rest⁺ involves: 129/Sv * 129S4/SvJae * C57BL/6	normal pigmentation phenotype	J:230341
Dct^tm1(cre)Bee/Dct⁺ Rest^tm1.1Yasu/Rest^tm1.1Yasu involves: 129/Sv * 129S4/SvJae * C57BL/6	head spot	J:230341
Rest^tm1.1Bban/Rest⁺ Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJaeSor * C57BL/6J	cochlear hair cell degeneration	J:265659
	impaired hearing	J:265659
	increased or absent threshold for auditory brainstem response	J:265659
Rest^tm1.1Bban/Rest⁺ Gfi1^tm1(cre)Gan/Gfi1⁺ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * FVB/N	cochlear inner hair cell degeneration	J:265659
	deafness	J:265659
Rest^tm1.1Jhsi/Rest^tm1.1Jhsi involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal neuron differentiation	J:174056
Rest^tm1.1Jhsi/Rest^tm1.1Jhsi Tg(CAG-cre)13Miya/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	embryonic lethality, complete penetrance	J:174056
Rest^tm1.1Whk/Rest^tm1.1Whk Tg(Six3-cre)69Frty/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2	abnormal retina ganglion layer morphology	J:167071
	abnormal retina progenitor cell morphology	J:167071
	increased retina ganglion cell number	J:167071
	thick retina ganglion layer	J:167071
	thick retina inner plexiform layer	J:167071
Rest^tm1.1Yasu/Rest⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J	belly spot	J:230341
	normal mortality/aging	J:230341
	normal nervous system phenotype	J:230341
Rest^tm1.1Yasu/Rest⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Dct-lacZ)A12Jkn/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal melanoblast morphology	J:230341
Rest^tm1.1Yasu/Rest⁺ Tg(Mpz-cre)26Mes/0 involves: 129S4/SvJae * C57BL/6 * FVB/NTac	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest⁺ Tg(KRT14-cre)1Cgn/0 involves: 129S4/SvJae * C57BL/6 * DBA/2	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest⁺ Tg(Tyr-cre)1Lru/Y involves: 129S4/SvJae * C57BL/6 * DBA/2	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest^tm1.1Yasu H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J	neonatal lethality, complete penetrance	J:230341
	normal nervous system phenotype	J:230341
Rest^tm1.1Yasu/Rest^tm1.1Yasu H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Dct-lacZ)A12Jkn/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal melanoblast morphology	J:230341
Rest^tm1.1Yasu/Rest^tm1.1Yasu Tg(KRT14-cre)1Cgn/0 involves: 129S4/SvJae * C57BL/6 * DBA/2	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest^tm1.1Yasu Tg(Mpz-cre)26Mes/0 involves: 129S4/SvJae * C57BL/6 * FVB/NTac	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest^tm1.1Yasu Tg(Tyr-cre)1Lru/Y involves: 129S4/SvJae * C57BL/6 * DBA/2	normal pigmentation phenotype	J:230341
Rest^tm1.1Yasu/Rest^tm1.2Yasu Alpl^tm1(cre)Nagy/Alpl⁺ involves: 129 * C57BL/6 * C57BL/6J	decreased primordial germ cell number	J:190948
	increased primordial germ cell apoptosis	J:190948
	normal reproductive system phenotype	J:190948
Rest^tm1.2Bban/Rest⁺ involves: 129S4/SvJaeSor * FVB/N	abnormal kinocilium morphology	J:265659
	abnormal outer hair cell stereociliary bundle morphology	J:265659
	abnormal utricle morphology	J:265659
	cochlear hair cell degeneration	J:265659
	cochlear inner hair cell degeneration	J:265659
	deafness	J:265659
	impaired balance	J:265659
	increased or absent threshold for auditory brainstem response	J:265659
	normal nervous system phenotype	J:265659
Rest^tm1And/Rest^tm1And involves: 129S7/SvEvBrd * C57BL/6J	abnormal midbrain development	J:50169
	abnormal somite development	J:50169
	embryonic growth retardation	J:50169
	embryonic lethality during organogenesis, complete penetrance	J:50169
	increased embryonic tissue cell apoptosis	J:50169
	small embryonic telencephalon	J:50169
Rest^tm1Mlit/Rest^tm1Mlit Tg(Eno2-cre)#Mlit/0 involves: 129S1/Sv * C57BL/6 * DBA	increased neuron apoptosis	J:173834
Rest^tm1Ymat/Rest^tm1Ymat involves: 129P2/OlaHsd * C57BL/6	abnormal cranial flexure morphology	J:190948
	abnormal forebrain morphology	J:190948
	decreased primordial germ cell number	J:190948
	embryonic lethality during organogenesis, complete penetrance	J:190948
	increased primordial germ cell apoptosis	J:190948
Rest^{tm2b(EUCOMM)Wtsi}/Rest⁺ C57BL/6N-Rest^{tm2b(EUCOMM)Wtsi}/Ieg	abnormal auditory brainstem response	J:211773
	decreased heart rate	J:211773
	decreased mean platelet volume	J:211773
Rest^{tm2b(EUCOMM)Wtsi}/Rest^{tm2b(EUCOMM)Wtsi} C57BL/6N-Rest^{tm2b(EUCOMM)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773

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