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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rest
RE1-silencing transcription factor
MGI:104897
40 phenotypes from 10 alleles in 15 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Dcttm1(cre)Bee/Dct+
Resttm1.1Yasu/Rest+
involves: 129/Sv * 129S4/SvJae * C57BL/6
normal pigmentation phenotype J:230341
Dcttm1(cre)Bee/Dct+
Resttm1.1Yasu/Resttm1.1Yasu
involves: 129/Sv * 129S4/SvJae * C57BL/6
head spot J:230341
Resttm1.1Bban/Rest+
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
involves: 129S4/SvJaeSor * C57BL/6J
cochlear hair cell degeneration J:265659
impaired hearing J:265659
increased or absent threshold for auditory brainstem response J:265659
Resttm1.1Bban/Rest+
Gfi1tm1(cre)Gan/Gfi1+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * FVB/N
cochlear inner hair cell degeneration J:265659
deafness J:265659
Resttm1.1Jhsi/Resttm1.1Jhsi
involves: 129S6/SvEvTac * C57BL/6 * SJL
abnormal neuron differentiation J:174056
Resttm1.1Jhsi/Resttm1.1Jhsi
Tg(CAG-cre)13Miya/0
involves: 129S6/SvEvTac * C57BL/6 * SJL
embryonic lethality, complete penetrance J:174056
Resttm1.1Whk/Resttm1.1Whk
Tg(Six3-cre)69Frty/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2
abnormal retinal ganglion layer morphology J:167071
abnormal retinal inner plexiform layer morphology J:167071
abnormal retinal progenitor cell morphology J:167071
increased retinal ganglion cell number J:167071
thick retinal ganglion layer J:167071
Resttm1.1Yasu/Rest+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J
belly spot J:230341
normal mortality/aging J:230341
normal nervous system phenotype J:230341
Resttm1.1Yasu/Rest+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Dct-LacZ)A12Jkn/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal melanoblast morphology J:230341
Resttm1.1Yasu/Rest+
Tg(Mpz-cre)26Mes/0
involves: 129S4/SvJae * C57BL/6 * FVB/NTac
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Rest+
Tg(KRT14-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * DBA/2
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Rest+
Tg(Tyr-cre)1Lru/Y
involves: 129S4/SvJae * C57BL/6 * DBA/2
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Resttm1.1Yasu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J
neonatal lethality, complete penetrance J:230341
normal nervous system phenotype J:230341
Resttm1.1Yasu/Resttm1.1Yasu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Dct-LacZ)A12Jkn/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal melanoblast morphology J:230341
Resttm1.1Yasu/Resttm1.1Yasu
Tg(KRT14-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * DBA/2
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Resttm1.1Yasu
Tg(Mpz-cre)26Mes/0
involves: 129S4/SvJae * C57BL/6 * FVB/NTac
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Resttm1.1Yasu
Tg(Tyr-cre)1Lru/Y
involves: 129S4/SvJae * C57BL/6 * DBA/2
normal pigmentation phenotype J:230341
Resttm1.1Yasu/Resttm1.2Yasu
Alpltm1(cre)Nagy/Alpl+
involves: 129 * C57BL/6 * C57BL/6J
decreased primordial germ cell number J:190948
increased primordial germ cell apoptosis J:190948
normal reproductive system phenotype J:190948
Resttm1.2Bban/Rest+
involves: 129S4/SvJaeSor * FVB/N
abnormal kinocilium morphology J:265659
abnormal outer hair cell stereociliary bundle morphology J:265659
abnormal utricle morphology J:265659
cochlear hair cell degeneration J:265659
cochlear inner hair cell degeneration J:265659
deafness J:265659
impaired balance J:265659
increased or absent threshold for auditory brainstem response J:265659
normal nervous system phenotype J:265659
Resttm1And/Resttm1And
involves: 129S7/SvEvBrd * C57BL/6J
abnormal midbrain development J:50169
abnormal somite development J:50169
embryonic growth retardation J:50169
embryonic lethality during organogenesis, complete penetrance J:50169
increased embryonic tissue cell apoptosis J:50169
small embryonic telencephalon J:50169
Resttm1Mlit/Resttm1Mlit
Tg(Eno2-cre)#Mlit/0
involves: 129S1/Sv * C57BL/6 * DBA
increased neuron apoptosis J:173834
Resttm1Ymat/Resttm1Ymat
involves: 129P2/OlaHsd * C57BL/6
abnormal cranial flexure morphology J:190948
abnormal forebrain morphology J:190948
decreased primordial germ cell number J:190948
embryonic lethality during organogenesis, complete penetrance J:190948
increased primordial germ cell apoptosis J:190948
Resttm2b(EUCOMM)Wtsi/Rest+
C57BL/6N-Resttm2b(EUCOMM)Wtsi/Ieg
aorta dilation J:211773
decreased heart rate J:211773
decreased threshold for auditory brainstem response J:211773
prolonged RR interval J:211773
Resttm2b(EUCOMM)Wtsi/Resttm2b(EUCOMM)Wtsi
C57BL/6N-Resttm2b(EUCOMM)Wtsi/Ieg
preweaning lethality, complete penetrance J:211773

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory