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Fancb
Gene Detail
Symbol

Name
ID
Fancb
Fanconi anemia, complementation group B
MGI:2448558
Synonyms
MGC:31411
Feature Type
protein coding gene
Genetic Map
Chromosome X
76.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:164980592-164997272 bp, + strand
From VEGA annotation of GRCm38

  16681 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:51880  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 1 zebrafish

HCOP human homology predictions: FANCB
Gene Tree: Fancb

Human
homologs
FANCB, Fanconi anemia, complementation group B
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2187
neXtProt AC: NX_Q8NB91

Human Synonyms: FA2, FAAP90, FAAP95, FAB, FACB

Human Chr (Location): Xp22.2; chrX:14796153-14873317 (-)  GRCh38.p2

Disease Associations: (3) Diseases Associated with Human FANCB

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from APF )
Interactions
Fancb interacts with 57 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process cellular response to DNA damage stimulus, DNA repair
Component Fanconi anaemia nuclear complex, nucleus
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000019556 (Evidence)
Ensembl Gene Model ENSMUSG00000047757 (Evidence)
Entrez Gene 237211 (Evidence)
UniGene 336317
DFCI TC1591025, TC1584521, TC1609292
DoTS DT.111031841, DT.94276944, DT.91378222, DT.97359313
NIA Mouse Gene Index U043805
Consensus CDS Project CCDS53242.1
International Mouse Phenotyping Consortium Status Fancb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019556 VEGA Gene Model | MGI Sequence Detail 16681 C57BL/6J ±  kb
transcript OTTMUST00000046697 VEGA | MGI Sequence Detail 2980 Not Applicable 
polypeptide OTTMUSP00000021096 VEGA | MGI Sequence Detail 862 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(7) UniProt(6)
Polymorphisms
SNPs within 2kb(52 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000007331 Fanconi anemia group B protein
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory