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Tsr1 Gene Detail
Summary
  • Symbol
    Tsr1
  • Name
    TSR1 20S rRNA accumulation
  • Synonyms
    mKIAA1401
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144566
    NCBI Gene: 104662
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:74898080-74909340 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.76 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144566
protein coding gene Chr11:74898071-74909342 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018701
protein coding gene Chr11:75613808-75625079 (+)
A/J MGP_AJ_G0018667
protein coding gene Chr11:72806836-72818117 (+)
AKR/J MGP_AKRJ_G0018637
protein coding gene Chr11:75014809-75027277 (+)
BALB/cJ MGP_BALBcJ_G0018641
protein coding gene Chr11:73175259-73186530 (+)
C3H/HeJ MGP_C3HHeJ_G0018454
protein coding gene Chr11:75019804-75031126 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019092
protein coding gene Chr11:77988646-78000606 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016727
protein coding gene Chr11:69832001-69843593 (+)
CAST/EiJ MGP_CASTEiJ_G0018008
protein coding gene Chr11:75401476-75413469 (+)
CBA/J MGP_CBAJ_G0018424
protein coding gene Chr11:81411008-81424097 (+)
DBA/2J MGP_DBA2J_G0018533
protein coding gene Chr11:72405385-72418262 (+)
FVB/NJ MGP_FVBNJ_G0018523
protein coding gene Chr11:71978655-71989919 (+)
LP/J MGP_LPJ_G0018604
protein coding gene Chr11:76206496-76217767 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018549
protein coding gene Chr11:82013608-82025207 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019132
protein coding gene Chr11:75204796-75216077 (+)
PWK/PhJ MGP_PWKPhJ_G0017779
protein coding gene Chr11:73104953-73115529 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017570
protein coding gene Chr11:74780029-74794051 (+)
WSB/EiJ MGP_WSBEiJ_G0018061
protein coding gene Chr11:75014593-75026809 (+)



Homology
more
  • Human Ortholog
    TSR1, TSR1 ribosome maturation factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TSR1, TSR1 ribosome maturation factor
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55720
    neXtProt AC: NX_Q2NL82
    UniProt: Q2NL82

  • Chr Location
    17p13.3; chr17:2322678-2337384 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 104662 NCBI Gene Model | MGI Sequence Detail 11261 C57BL/6J ±  kb
transcript NM_177325 RefSeq | MGI Sequence Detail 3395 C57BL/6  
polypeptide Q5SWD9 UniProt | EBI | MGI Sequence Detail 803 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144422
References
more
  • Summaries
    All 40
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory