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Tsr1 Gene Detail
Summary
  • Symbol
    Tsr1
  • Name
    TSR1 20S rRNA accumulation
  • Synonyms
    mKIAA1401
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144566
    NCBI Gene: 104662
Location & Maps
more
  • Sequence Map
    Chr11:74898071-74909342 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11272 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.76 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TSR1, TSR1, ribosome maturation factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TSR1, TSR1, ribosome maturation factor
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55720
    neXtProt AC: NX_Q2NL82

  • Chr Location
    17p13.3; chr17:2322678-2337384 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Targeted
    4
  • Genomic Mutations
    2 involving Tsr1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006188 VEGA Gene Model | MGI Sequence Detail 11272 C57BL/6J ±  kb
transcript OTTMUST00000013944 VEGA | MGI Sequence Detail 3389 Not Applicable  
polypeptide OTTMUSP00000006478 VEGA | MGI Sequence Detail 803 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    49 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016766 pre-rRNA-processing protein TSR1
  • InterPro Domains
    IPR012948 AARP2CN
    IPR030387 Bms1/Tsr1-type G domain
    IPR007034 Ribosome biogenesis protein BMS1/TSR1, C-terminal
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144422
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 17
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory