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Ppfia1
Gene Detail
Symbol

Name
ID
Ppfia1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
MGI:1924750
Synonyms
C030014K08Rik, liprin, Liprin-alpha1, Liprin-alpha1a, Liprin-alpha1b
Feature Type
protein coding gene
Genetic Map
Chromosome 7
88.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:144476755-144553729 bp, - strand
From VEGA annotation of GRCm38

  76975 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20802  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PPFIA1
Gene Tree: Ppfia1

Human
homologs
PPFIA1, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8500
neXtProt AC: NX_Q13136

Human Synonyms: LIP1, LIP.1, LIPRIN

Human Chr (Location): 11q13.3; chr11:70270687-70384501 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ppfia1 interacts with 251 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (29)    Tissues (29)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 29
cDNA source data(161)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ppfia1    NEW 
Molecular
reagents
All nucleic(161) cDNA(161)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000043428 (Evidence)
Ensembl Gene Model ENSMUSG00000037519 (Evidence)
Entrez Gene 233977 (Evidence)
UniGene 490347
DFCI TC1602053, TC1600458, TC1621032
DoTS DT.94213688, DT.40177260, DT.101722392, DT.94213692
NIA Mouse Gene Index U365840, U375679, U029525
Consensus CDS Project CCDS52464.1, CCDS59738.1
International Mouse Phenotyping Consortium Status Ppfia1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043428 VEGA Gene Model | MGI Sequence Detail 76975 C57BL/6J ±  kb
transcript OTTMUST00000113932 VEGA | MGI Sequence Detail 4829 Not Applicable 
polypeptide OTTMUSP00000063626 VEGA | MGI Sequence Detail 1266 Not Applicable 

For the selected sequences
All sequences(108) RefSeq(44) UniProt(6)
Polymorphisms
SNPs within 2kb(378 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR021129 Sterile alpha motif, type 1
InterPro IPR011510 Sterile alpha motif, type 2
Protein Ontology PR:000013068 liprin-alpha-1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:201692 Wentzel C, et al., mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking. Neuron. 2013 Jun 19;78(6):1012-23
All references(35)
Other
accession IDs
MGI:2142372

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory