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Ssbp3 Gene Detail
Summary
  • Symbol
    Ssbp3
  • Name
    single-stranded DNA binding protein 3
  • Synonyms
    2610021L12Rik, 2610200M23Rik, 5730488C10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919725
    NCBI Gene: 72475
  • Gene Overview
    MyGene.info: SSBP3
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106911470-107049694 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 49.90 cM, cytoband C7
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    840 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919725
protein coding gene Chr4:106910701-107049694 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028528
protein coding gene Chr4:107568119-107718071 (+)
A/J MGP_AJ_G0028491
protein coding gene Chr4:103717729-103857057 (+)
AKR/J MGP_AKRJ_G0028438
protein coding gene Chr4:106249923-106392757 (+)
BALB/cJ MGP_BALBcJ_G0028510
protein coding gene Chr4:103908176-104048222 (+)
C3H/HeJ MGP_C3HHeJ_G0028224
protein coding gene Chr4:106998726-107148189 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028950
protein coding gene Chr4:111453500-111599402 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026241
protein coding gene Chr4:98995550-99134029 (+)
CAST/EiJ MGP_CASTEiJ_G0027660
protein coding gene Chr4:104812854-104958544 (+)
CBA/J MGP_CBAJ_G0028193
protein coding gene Chr4:115058142-115210185 (+)
DBA/2J MGP_DBA2J_G0028341
protein coding gene Chr4:103335700-103474659 (+)
FVB/NJ MGP_FVBNJ_G0028309
protein coding gene Chr4:102197340-102340561 (+)
LP/J MGP_LPJ_G0028442
protein coding gene Chr4:107769515-107915813 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028335
protein coding gene Chr4:120372600-120513390 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028986
protein coding gene Chr4:106492514-106633022 (+)
PWK/PhJ MGP_PWKPhJ_G0027386
protein coding gene Chr4:101580439-101722697 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027210
protein coding gene Chr4:103890025-104038086 (+)
WSB/EiJ MGP_WSBEiJ_G0027741
protein coding gene Chr4:106673081-106817320 (+)



Homology
more
  • Human Ortholog
    SSBP3, single stranded DNA binding protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SSBP3, single stranded DNA binding protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CSDP, SSDP, SSDP1
  • Links
    NCBI Gene ID: 23648
    neXtProt AC: NX_Q9BWW4
    UniProt: Q9BWW4

  • Chr Location
    1p32.3; chr1:54225431-54413479 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 23411
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SSBP3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    37 phenotypes from 3 alleles in 3 genetic backgrounds
    3 phenotypes from multigenic genotypes
    1 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Embryos homozygous for a gene trap mutation that deletes the proline-rich domain show a severe anterior truncation and a lethal headless phenotype (loss of fore- and midbrain). Embryos homozygous for a gene trap mutation which retains most of the proline-rich domain show normal head development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72475 NCBI Gene Model | MGI Sequence Detail 138225 C57BL/6J ±  kb
    transcript NM_023672 RefSeq | MGI Sequence Detail 3211 C57BL/6  
    polypeptide Q9D032 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1917840, MGI:1919697, MGI:2140399, MGI:2140595
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 6
      Gene Ontology 7
      Phenotypes 13
    • Earliest
      J:57548 Raval-Fernandes S, et al., Cloning of a cDNA encoding a sequence-specific single-stranded-DNA-binding protein from Rattus norvegicus. Gene. 1999 Sep 3;237(1):201-7
    • Latest
      J:234058 Galloway JR, et al., SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes. Mol Endocrinol. 2015 Dec;29(12):1774-86

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory