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Hsd17b6 Gene Detail
Summary
  • Symbol
    Hsd17b6
  • Name
    hydroxysteroid (17-beta) dehydrogenase 6
  • Synonyms
    17betaHSD9, Hsd17b9, Rdh8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351670
    NCBI Gene: 27400
  • Gene Overview
    MyGene.info: HSD17B6
Location & Maps
more
  • Sequence Map
    Chr10:127990941-128000678 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9738 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 76.39 cM, cytoband D3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    HSD17B6, hydroxysteroid 17-beta dehydrogenase 6
  • Vertebrate Orthologs
    5
  • Human Ortholog
    HSD17B6, hydroxysteroid 17-beta dehydrogenase 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HSE, RODH, SDR9C6
  • Links
    NCBI Gene ID: 8630
    neXtProt AC: NX_O14756

  • Chr Location
    12q13; chr12:56752449-56787790 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025396 Ensembl Gene Model | MGI Sequence Detail 9738 C57BL/6J ±  kb
transcript ENSMUST00000026462 Ensembl | MGI Sequence Detail 1392 Not Applicable  
polypeptide ENSMUSP00000026462 Ensembl | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    191 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:58333 Su J, et al., Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase. Endocrinology. 1999 Nov;140(11):5275-84
  • Latest
    J:216177 Labialle S, et al., The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory