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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
a
nonagouti
MGI:1855937
Summary 119 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
a/a involves: SM/J MGI:3789001
hm2
a/a Not Specified MGI:5460860
ht3
au/a (C3H/HeH x 101/H)F1 MGI:2687037
ht4
ax/a B6.Cg-ax MGI:5085916
ht5
Ay/a B6.Cg-Ay/J MGI:3799322
ht6
a/Aw-22J C57BL/10Rk MGI:5446397
ht7
Aw-46J/a C57BL/6J MGI:2181394
ht8
Asy/a C57BL/6J MGI:3052033
ht9
a/Aw-20J C57BL/6J MGI:5446384
ht10
Aw-26J/a C57BL/6J MGI:5463493
ht11
Aw-27J/a C57BL/6J MGI:5463495
ht12
atd/a C57BL/6J-atd/J MGI:3819402
ht13
Atm1Brd/a C57BL/6N-Atm1Brd MGI:3849879
ht14
Atm1.1Arte/a C57BL/6NTac-Atm1.1Arte/a MGI:5585625
ht15
a/a6H involves: 101/H * C3H/HeH MGI:3051515
ht16
al/a involves: 101/H * C3H/HeH MGI:3611222
ht17
a/a13H involves: 101/H * C3H/HeH MGI:5299221
ht18
a/a17H involves: 101/H * C3H/HeH MGI:5299224
ht19
am/a involves: 101/Rl * C3H/Rl MGI:4829948
ht20
ax/a involves: 101/Rl * C3H/Rl MGI:5085915
ht21
a/a19H involves: C3H/HeH MGI:5299235
ht22
Avy/a involves: C3H/HeJ * C57BL/6 MGI:3772367
ht23
am-J/a involves: C3H/HeJ * C57BL/6J MGI:3805305
ht24
Avy/a involves: C57BL/6J MGI:3778284
ht25
Aw-15J/a involves: C57BL/6J * DBA/2J MGI:5444873
ht26
Ay/a involves: KK MGI:3760281
ht27
Aw/a involves: SM/J MGI:3789002
ht28
ajl10/a Not Specified MGI:3047806
ht29
ajl41/a Not Specified MGI:3047815
ht30
ajl85/a Not Specified MGI:3047817
ht31
a/atwp Not Specified MGI:4367209
ht32
a/a20H Not Specified MGI:5299236
cx33
a/a
Hps6ru/Hps6ru
B6.Cg-Hps6ru MGI:3805043
cx34
Ay/a
Sik2tm1Htake/Sik2+
C57BL/6-Sik2tm1Htake MGI:5609871
cx35
a/a
KitW-2J/Kit+
C57BL/6J MGI:3813609
cx36
a/a
Mlphln/Mlphln
Tyrp1b/Tyrp1b
C57L/J MGI:3052536
cx37
a/a
Pax3Sp-1H/Pax3Sp-1H
involves: 101/H * C3H/HeH * C57BL/6 MGI:5636497
cx38
Ay/a
Npbwr1tm1Rck/Npbwr1tm1Rck
involves: 129P/Ola * C57BL/6J MGI:3526898
cx39
Ay/a
Apoetm1Unc/Apoetm1Unc
involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl MGI:5297860
cx40
Ay/a
Apoetm1Unc/Apoetm1Unc
Ccr2tm1Mae/Ccr2tm1Mae
involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl MGI:5297861
cx41
Avy/a
Axin1Fu/Axin1+
involves: 129P4/RrRk * C67BL/6J MGI:3778273
cx42
Ay/a
Agrptm2(DTR)Rpa/Agrp+
involves: 129S4/SvJaeSor * KK/Upj MGI:3776093
cx43
a/A
Pomctm1Sora/Pomctm1Sora
involves: 129S6/SvEvTac MGI:3805940
cx44
a/A
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
involves: 129S6/SvEvTac * C57BL/6Ha MGI:3805942
cx45
a/a
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
involves: 129S6/SvEvTac * C57BL/6Ha MGI:3805943
cx46
Aw/a
Corintm1Bamo/Corintm1Bamo
involves: 129X1/SvJ * C57BL/6 * FVB/N MGI:3772887
cx47
a/a
Corintm1Bamo/Corintm1Bamo
involves: 129X1/SvJ * C57BL/6 * FVB/N MGI:3772889
cx48
a/a
Oca2p-J/Oca2p-J
involves: C3H/HeJ MGI:4454423
cx49
a/a
Lystbg/Lystbg
Oca2p-J/Oca2p-J
involves: C3H/HeJ * C3H/Rl * C57BL/6J MGI:4454430
cx50
a/a
Rab27aash/Rab27aash
involves: C3H/HeSnJ * C57BL/6J MGI:5505784
cx51
a/a
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J MGI:4454426
cx52
a/a
Lystbg/Lystbg
Tyrc/Tyrc
involves: C3H/Rl * C57BL/6J MGI:4454429
cx53
a/a
Hps6ru/Hps6ru
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J MGI:4454431
cx54
a/a
Lystbg/Lystbg
Tyrp1b/Tyrp1b
involves: C3H/Rl * C57BL/6J MGI:4454432
cx55
Ay/a
Rmi1Gt(pUHachi)0283Imeg/Rmi1+
involves: C57BL/6 * KK MGI:4936833
cx56
a/a
Rmi1Gt(pUHachi)0283Imeg/Rmi1+
involves: C57BL/6 * KK MGI:4936834
cx57
a/a
Tyrc/Tyrc
involves: C57BL/6J MGI:4454419
cx58
a/a
Hps6ru/Hps6ru
involves: C57BL/6J MGI:4454424
cx59
a/a
Tyrp1b/Tyrp1b
involves: C57BL/6J MGI:4454425
cx60
a/a
Bloc1s6pa/Bloc1s6pa
involves: C57BL/6J MGI:4454434
cx61
a/a
Mregdsu/Mregdsu
Hps6ru/Hps6ru
involves: C57BL/6J MGI:5466757
cx62
a/a
Zc3h4KK/Zc3h4KK
involves: C57BL/6J * KK-Ay MGI:2175418
cx63
a/Ay
Zc3h4KK/Zc3h4KK
involves: C57BL/6J * KK-Ay MGI:2679980
cx64
a/Ay
Zc3h4C57BL/6J/Zc3h4KK
involves: C57BL/6J * KK-Ay MGI:2679981
cx65
a/Ay
Bwq2KK/Bwq2KK
involves: C57BL/6J * KK-Ay MGI:3487268
cx66
a/Ay
Bwq10C57BL/6J/Bwq10C57BL/6J
involves: C57BL/6J * KK-Ay MGI:3773901
cx67
a/Ay
Guq1KK/Guq1KK
involves: C57BL/6J * KK-Ay MGI:3773902
cx68
a/Ay
Guq2C57BL/6J/Guq2C57BL/6J
involves: C57BL/6J * KK-Ay MGI:3773903
cx69
Ay/a
Mssq1KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833436
cx70
a/a
Mssq1KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833437
cx71
Ay/a
Mssq2C57BL/6JJcl/Mssq2KK/TaJcl
involves: C57BL/6JJcl * KK/TaJcl MGI:3833439
cx72
Ay/a
Mssq3KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833448
cx73
a/a
Mssq3KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833451
cx74
Ay/a
Mssq4KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833452
cx75
a/a
Mssq4KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833453
cx76
Ay/a
Mssq5C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833454
cx77
a/a
Mssq5C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833455
cx78
Ay/a
Mssq6C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833456
cx79
a/a
Mssq6C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833457
cx80
Ay/a
Mssq6KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833460
cx81
a/a
Mssq6KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833461
cx82
Ay/a
Mssq7KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833471
cx83
a/a
Mssq7KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833472
cx84
a/a
Mssq8C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833967
cx85
a/a
Mssq9C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833968
cx86
Ay/a
Mssq9C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833969
cx87
a/a
Mssq10KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833970
cx88
Ay/a
Mssq10KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833971
cx89
a/a
Mssq11KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833972
cx90
Ay/a
Mssq11KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833973
cx91
a/a
Mssq12KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833974
cx92
Ay/a
Mssq12KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833975
cx93
a/a
Mssq13KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833976
cx94
Ay/a
Mssq13KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833977
cx95
a/a
Mssq13C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833978
cx96
Ay/a
Mssq13C57BL/6JJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833979
cx97
a/a
Mssq14KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833980
cx98
Ay/a
Mssq14KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833981
cx99
a/a
Mssq15C57BL/6JJcl/Mssq15KK/TaJcl
involves: C57BL/6JJcl * KK/TaJcl MGI:3833982
cx100
a/a
Mssq16KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833983
cx101
Ay/a
Mssq16KK/TaJcl/?
involves: C57BL/6JJcl * KK/TaJcl MGI:3833984
cx102
a/a
Mlphln/Mlphln
involves: C57BL/J * C57BR MGI:4454435
cx103
a/a
Myo5ad/Myo5a+
Oca2p/Oca2+
Tyrp1B-lt/Tyrp1+
involves: C58 * CT/Ch MGI:3795191
cx104
a/a
Myo5ad/Myo5ad
involves: DBA/2J MGI:4454433
cx105
Ay/a
Dmbx1tm1Sse/Dmbx1tm1Sse
involves: ICR MGI:3759412
cx106
a/a
Tyrc-i/Tyrc-i
involves: STOCK Tyrc-r MGI:2663195
cx107
a/a
Tyrp1B-lt/Tyrp1B-lt
Not Specified MGI:3795183
cx108
a/a
Tyrp1B-lt/Tyrp1+
Not Specified MGI:3795185
cx109
A/a
Tyrp1B-lt/Tyrp1B-lt
Not Specified MGI:3795188
cx110
Ay/a
Tyrp1B-lt/?
Not Specified MGI:3795189
cx111
a/a
U/U
Not Specified MGI:3844552
cx112
a/a
Oca2p/Oca2p
Not Specified MGI:3844692
cx113
a/a
Hps6ru/Hps6ru
Not Specified MGI:4361342
cx114
a/a
Tyrp1b/Tyrp1b
wad/wad+
Not Specified MGI:4818897
cx115
a/a
Tyrp1b/Tyrp1b
wad/wad
Not Specified MGI:4818908
cx116
Ay/a
Ednrbs/Ednrbs
Not Specified MGI:5086233
cx117
a/a
Myo5ad/Myo5ad
Not Specified MGI:5440857
cx118
a/a
Tyrp1b/Tyrp1b
Not Specified MGI:5440939
cx119
a/a
Mlphln/Mlphln
Not Specified MGI:5468335


Genotype
MGI:3789001
hm1
Allelic
Composition
a/a
Genetic
Background
involves: SM/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• total cortex and x-zone of adrenal cortex are of similar thickness to Aw/a or Aw/ Aw 70-day old virgin mice (J:19308)
• X-zone is composed exclusively of non-vacuolated cells (J:19308)
• zona glomerulosa, zona fasciculata, and zona reticularis are morphologically similar between genotypes (J:19308)
• total cortex and x-zone of adrenal cortex are of similar thickness to Aw/a or Aw/ Aw 70-day old virgin mice (J:19308)
• X-zone is composed exclusively of non-vacuolated cells (J:19308)
• zona glomerulosa, zona fasciculata, and zona reticularis are morphologically similar between genotypes (J:19308)




Genotype
MGI:5460860
hm2
Allelic
Composition
a/a
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• hairs lack the yellow pigment band found in the wild-type agouti black coat (J:36414)
• hairs lack the yellow pigment band found in the wild-type agouti black coat (J:36414)
• hairs are black except for yellow hairs around ears, mammae, and perineum (J:36414)
• hairs are black except for yellow hairs around ears, mammae, and perineum (J:36414)

pigmentation
• hairs lack the yellow pigment band found in the wild-type agouti black coat (J:36414)
• hairs lack the yellow pigment band found in the wild-type agouti black coat (J:36414)
• hairs are black except for yellow hairs around ears, mammae, and perineum (J:36414)
• hairs are black except for yellow hairs around ears, mammae, and perineum (J:36414)




Genotype
MGI:2687037
ht3
Allelic
Composition
au/a
Genetic
Background
(C3H/HeH x 101/H)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
au mutation (2 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• with a, coat is nonagouti on the back with dark agouti belly and pinna hairs are yellow (J:13694)
• with at, coat is nonagouti on the back with tan belly and pinna hairs are yellow (J:13694)
• with a, coat is nonagouti on the back with dark agouti belly and pinna hairs are yellow (J:13694)
• with at, coat is nonagouti on the back with tan belly and pinna hairs are yellow (J:13694)

integument
• with a, coat is nonagouti on the back with dark agouti belly and pinna hairs are yellow (J:13694)
• with at, coat is nonagouti on the back with tan belly and pinna hairs are yellow (J:13694)
• with a, coat is nonagouti on the back with dark agouti belly and pinna hairs are yellow (J:13694)
• with at, coat is nonagouti on the back with tan belly and pinna hairs are yellow (J:13694)




Genotype
MGI:5085916
ht4
Allelic
Composition
ax/a
Genetic
Background
B6.Cg-ax
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
ax mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• at 3-4 weeks of age, mice of this genotype have more yellow-banded agouti hair on their sides than do homozygous non-agouti mice (J:11953)
• at 3-4 weeks of age, mice of this genotype have more yellow-banded agouti hair on their sides than do homozygous non-agouti mice (J:11953)
• at 3-4 weeks of age, a paler ventrum distinguishes this genotype from homozygous non-agouti or mice (J:11953)
• at 3-4 weeks of age, a paler ventrum distinguishes this genotype from homozygous non-agouti or mice (J:11953)

pigmentation
• at 3-4 weeks of age, mice of this genotype have more yellow-banded agouti hair on their sides than do homozygous non-agouti mice (J:11953)
• at 3-4 weeks of age, mice of this genotype have more yellow-banded agouti hair on their sides than do homozygous non-agouti mice (J:11953)
• at 3-4 weeks of age, a paler ventrum distinguishes this genotype from homozygous non-agouti or mice (J:11953)
• at 3-4 weeks of age, a paler ventrum distinguishes this genotype from homozygous non-agouti or mice (J:11953)




Genotype
MGI:3799322
ht5
Allelic
Composition
Ay/a
Genetic
Background
B6.Cg-Ay/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Ay/a mouse

behavior/neurological
• the stress of isolation, restraint, or ip injection inhibits feeding (J:102986)
• the stress of isolation, restraint, or ip injection inhibits feeding (J:102986)

pigmentation
• tyrosinase levels in hairbulb melanocytes ,as determined by 35S methionine incorporation and immunotitration, are reduced in comparison to a/a controls (J:1295)
• decreased tyrosinase suggests the production of predominantly phaeomelanin (yellow) (J:1295)
• tyrosinase levels in hairbulb melanocytes ,as determined by 35S methionine incorporation and immunotitration, are reduced in comparison to a/a controls (J:1295)
• decreased tyrosinase suggests the production of predominantly phaeomelanin (yellow) (J:1295)

integument
• tyrosinase levels in hairbulb melanocytes ,as determined by 35S methionine incorporation and immunotitration, are reduced in comparison to a/a controls (J:1295)
• decreased tyrosinase suggests the production of predominantly phaeomelanin (yellow) (J:1295)
• tyrosinase levels in hairbulb melanocytes ,as determined by 35S methionine incorporation and immunotitration, are reduced in comparison to a/a controls (J:1295)
• decreased tyrosinase suggests the production of predominantly phaeomelanin (yellow) (J:1295)




Genotype
MGI:5446397
ht6
Allelic
Composition
a/Aw-22J
Genetic
Background
C57BL/10Rk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-22J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)

pigmentation
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)




Genotype
MGI:2181394
ht7
Allelic
Composition
Aw-46J/a
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-46J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype



Genotype
MGI:3052033
ht8
Allelic
Composition
Asy/a
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Asy mutation (2 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• dark or sooty yellow due to black tips on otherwise yellow hair (J:13497)
• dark or sooty yellow due to black tips on otherwise yellow hair (J:13497)

integument
• dark or sooty yellow due to black tips on otherwise yellow hair (J:13497)
• dark or sooty yellow due to black tips on otherwise yellow hair (J:13497)




Genotype
MGI:5446384
ht9
Allelic
Composition
a/Aw-20J
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-20J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)

pigmentation
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:79402)




Genotype
MGI:5463493
ht10
Allelic
Composition
Aw-26J/a
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-26J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the ventral and flank coat is agouti instead of the expected non-agouti black (J:78801)
• the ventral and flank coat is agouti instead of the expected non-agouti black (J:78801)
• the ventrum is white or "light" (J:78801)
• the ventrum is white or "light" (J:78801)

pigmentation
• the ventral and flank coat is agouti instead of the expected non-agouti black (J:78801)
• the ventral and flank coat is agouti instead of the expected non-agouti black (J:78801)
• the ventrum is white or "light" (J:78801)
• the ventrum is white or "light" (J:78801)




Genotype
MGI:5463495
ht11
Allelic
Composition
Aw-27J/a
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-27J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the ventrum and flank coat is agouti (J:78801)
• the ventrum and flank coat is agouti (J:78801)
• the ventrum is white or "light" (J:78801)
• the ventrum is white or "light" (J:78801)

pigmentation
• the ventrum and flank coat is agouti (J:78801)
• the ventrum and flank coat is agouti (J:78801)
• the ventrum is white or "light" (J:78801)
• the ventrum is white or "light" (J:78801)




Genotype
MGI:3819402
ht12
Allelic
Composition
atd/a
Genetic
Background
C57BL/6J-atd/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
atd mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• the first coat has a tan belly with agouti hairs among the mostly black hairs on the side of the body, and after the first molt the agouti hairs spread over the back so that the back appears to be a darkened agouti color, instead of black (J:13082)
• appearance resembles Aw/? (J:13082)
• the first coat has a tan belly with agouti hairs among the mostly black hairs on the side of the body, and after the first molt the agouti hairs spread over the back so that the back appears to be a darkened agouti color, instead of black (J:13082)
• appearance resembles Aw/? (J:13082)

integument
• the first coat has a tan belly with agouti hairs among the mostly black hairs on the side of the body, and after the first molt the agouti hairs spread over the back so that the back appears to be a darkened agouti color, instead of black (J:13082)
• appearance resembles Aw/? (J:13082)
• the first coat has a tan belly with agouti hairs among the mostly black hairs on the side of the body, and after the first molt the agouti hairs spread over the back so that the back appears to be a darkened agouti color, instead of black (J:13082)
• appearance resembles Aw/? (J:13082)




Genotype
MGI:3849879
ht13
Allelic
Composition
Atm1Brd/a
Genetic
Background
C57BL/6N-Atm1Brd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Atm1Brd mutation (62 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• mice heterozygous for this targeted reversion to agouti on an otherwise normal C57BL/6N background have uniformly agouti coats, the hairs on both dorsum and ventrum having a subapical yellow band; this differs from the phenotype of a spontaneous revertant of nonagouti that occurred in C57BL/6J, Aw-J, which results in a light- or white-bellied agouti coat (J:149352)
• mice heterozygous for this targeted reversion to agouti on an otherwise normal C57BL/6N background have uniformly agouti coats, the hairs on both dorsum and ventrum having a subapical yellow band; this differs from the phenotype of a spontaneous revertant of nonagouti that occurred in C57BL/6J, Aw-J, which results in a light- or white-bellied agouti coat (J:149352)

integument
N
• mice heterozygous for this targeted reversion to agouti on an otherwise normal C57BL/6N background have uniformly agouti coats, the hairs on both dorsum and ventrum having a subapical yellow band; this differs from the phenotype of a spontaneous revertant of nonagouti that occurred in C57BL/6J, Aw-J, which results in a light- or white-bellied agouti coat (J:149352)
• mice heterozygous for this targeted reversion to agouti on an otherwise normal C57BL/6N background have uniformly agouti coats, the hairs on both dorsum and ventrum having a subapical yellow band; this differs from the phenotype of a spontaneous revertant of nonagouti that occurred in C57BL/6J, Aw-J, which results in a light- or white-bellied agouti coat (J:149352)




Genotype
MGI:5585625
ht14
Allelic
Composition
Atm1.1Arte/a
Genetic
Background
C57BL/6NTac-Atm1.1Arte/a
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Atm1.1Arte mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)

normal phenotype
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)

pigmentation
N
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)
• mice bearing this mutation on the C57BL/6NTac background exhibit a change in coat pigmentation from the characteristic black of the background strain to the wild-type agouti pattern, i.e., black and yellow banding of individual hairs. (J:213411)




Genotype
MGI:3051515
ht15
Allelic
Composition
a/a6H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
a6H mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• with nonagouti the coat color is umbrous with yellow pinna hairs (J:5021)
• with nonagouti the coat color is umbrous with yellow pinna hairs (J:5021)
• pinna hairs are yellow, unexpected for this genotype (J:5021)
• pinna hairs are yellow, unexpected for this genotype (J:5021)

integument
• with nonagouti the coat color is umbrous with yellow pinna hairs (J:5021)
• with nonagouti the coat color is umbrous with yellow pinna hairs (J:5021)
• pinna hairs are yellow, unexpected for this genotype (J:5021)
• pinna hairs are yellow, unexpected for this genotype (J:5021)




Genotype
MGI:3611222
ht16
Allelic
Composition
al/a
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
al mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• appears as aa, homozygous nonagouti black (J:9799)
• appears as aa, homozygous nonagouti black (J:9799)




Genotype
MGI:5299221
ht17
Allelic
Composition
a/a13H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
a13H mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• umbrous-like (J:90559)
• umbrous-like (J:90559)

pigmentation
• umbrous-like (J:90559)
• umbrous-like (J:90559)




Genotype
MGI:5299224
ht18
Allelic
Composition
a/a17H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
a17H mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• nonagouti (J:90559)
• nonagouti (J:90559)

pigmentation
• nonagouti (J:90559)
• nonagouti (J:90559)




Genotype
MGI:4829948
ht19
Allelic
Composition
am/a
Genetic
Background
involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
am mutation (2 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• Background Sensitivity: there is a continuum of color pattern ranging from all black indistinguishable from mice with a ae genotype, see ae , to degrees of yellow mottling on a black background, to mice with an agouti coat color pattern (J:5964)
• Background Sensitivity: the genetic background of the mother influences the coat pattern of the offspring (J:5964)
• Background Sensitivity: there is a continuum of color pattern ranging from all black indistinguishable from mice with a ae genotype, see ae , to degrees of yellow mottling on a black background, to mice with an agouti coat color pattern (J:5964)
• Background Sensitivity: the genetic background of the mother influences the coat pattern of the offspring (J:5964)
• mice are mottled with agouti and nonagouti patches of fur with hairs of both types intermingled at the pattern edges (J:29504)
• mice are mottled with agouti and nonagouti patches of fur with hairs of both types intermingled at the pattern edges (J:29504)
• matings of genotype am/a to a/a mice produce about 50% mottled offspring (J:29504)
• matings of genotype am/a to a/a mice produce about 50% mottled offspring (J:29504)

other phenotype
• the genetic background of the mother influences the coat pattern of the offspring (J:5964)
• the genetic background of the mother influences the coat pattern of the offspring (J:5964)

integument
• Background Sensitivity: there is a continuum of color pattern ranging from all black indistinguishable from mice with a ae genotype, see ae , to degrees of yellow mottling on a black background, to mice with an agouti coat color pattern (J:5964)
• Background Sensitivity: the genetic background of the mother influences the coat pattern of the offspring (J:5964)
• Background Sensitivity: there is a continuum of color pattern ranging from all black indistinguishable from mice with a ae genotype, see ae , to degrees of yellow mottling on a black background, to mice with an agouti coat color pattern (J:5964)
• Background Sensitivity: the genetic background of the mother influences the coat pattern of the offspring (J:5964)
• mice are mottled with agouti and nonagouti patches of fur with hairs of both types intermingled at the pattern edges (J:29504)
• mice are mottled with agouti and nonagouti patches of fur with hairs of both types intermingled at the pattern edges (J:29504)
• matings of genotype am/a to a/a mice produce about 50% mottled offspring (J:29504)
• matings of genotype am/a to a/a mice produce about 50% mottled offspring (J:29504)




Genotype
MGI:5085915
ht20
Allelic
Composition
ax/a
Genetic
Background
involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
ax mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the coat is slightly paler than that of a homozygous non-agouti coat (J:174047)
• the coat is slightly paler than that of a homozygous non-agouti coat (J:174047)

pigmentation
• the coat is slightly paler than that of a homozygous non-agouti coat (J:174047)
• the coat is slightly paler than that of a homozygous non-agouti coat (J:174047)




Genotype
MGI:5299235
ht21
Allelic
Composition
a/a19H
Genetic
Background
involves: C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
a19H mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• nonagouti (J:90559)
• nonagouti (J:90559)

pigmentation
• nonagouti (J:90559)
• nonagouti (J:90559)




Genotype
MGI:3772367
ht22
Allelic
Composition
Avy/a
Genetic
Background
involves: C3H/HeJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Avy mutation (7 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Spectrum of coat colors in Avy/a mice

growth/size/body

pigmentation
• variable coat color ranging from yellow, mosaic yellow/agouti, or pseudoagouti (J:117156)
• variable coat color ranging from yellow, mosaic yellow/agouti, or pseudoagouti (J:117156)

tumorigenesis

integument
• variable coat color ranging from yellow, mosaic yellow/agouti, or pseudoagouti (J:117156)
• variable coat color ranging from yellow, mosaic yellow/agouti, or pseudoagouti (J:117156)

cellular
• sires mated with a/a dams, but not dams mated with a/a sires, that were supplemented with methyl donors ((folate, choline, betaine, vitamin B12, zinc, and methionine) during pregnancy show a significant shift in the spectrum of color phenotypes toward pseudoagouti, indicating that in utero methyl donor supplementation affects the somatic epigenetic state of the Avy allele only when the allele is derived from the male (J:117156)
• F1 pseudoagouti females that had been exposed to methyl donors in utero from E8.5 to E15.5 and mated to a/a males without further methyl donor supplementation, produce offspring (F2) showing a sift toward pseudoagouti coloration, indicating that diet/environment has an enduring influence on succeeding generations, independent of later changes in diet (J:117156)
• sires mated with a/a dams, but not dams mated with a/a sires, that were supplemented with methyl donors ((folate, choline, betaine, vitamin B12, zinc, and methionine) during pregnancy show a significant shift in the spectrum of color phenotypes toward pseudoagouti, indicating that in utero methyl donor supplementation affects the somatic epigenetic state of the Avy allele only when the allele is derived from the male (J:117156)
• F1 pseudoagouti females that had been exposed to methyl donors in utero from E8.5 to E15.5 and mated to a/a males without further methyl donor supplementation, produce offspring (F2) showing a sift toward pseudoagouti coloration, indicating that diet/environment has an enduring influence on succeeding generations, independent of later changes in diet (J:117156)

Mouse Models of Human Disease
OMIM ID Ref(s)
Obesity 601665 J:13142 , J:117156




Genotype
MGI:3805305
ht23
Allelic
Composition
am-J/a
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
am-J mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• found in both heterozygotes and homozygotes and ranges in color from almost extreme non-agouti with little ticking to full agouti with no mottling (J:16570)
• found in both heterozygotes and homozygotes and ranges in color from almost extreme non-agouti with little ticking to full agouti with no mottling (J:16570)

integument
• found in both heterozygotes and homozygotes and ranges in color from almost extreme non-agouti with little ticking to full agouti with no mottling (J:16570)
• found in both heterozygotes and homozygotes and ranges in color from almost extreme non-agouti with little ticking to full agouti with no mottling (J:16570)




Genotype
MGI:3778284
ht24
Allelic
Composition
Avy/a
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Avy mutation (7 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation

integument

cellular
• this allele is heavily methylated in the sperm of agouti colored males but hypomethylated in the sperm of yellow males (J:82396)
• this allele is heavily methylated in the sperm of agouti colored males but hypomethylated in the sperm of yellow males (J:82396)




Genotype
MGI:5444873
ht25
Allelic
Composition
Aw-15J/a
Genetic
Background
involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw-15J mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:78474)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:78474)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:78474)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:78474)

pigmentation
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:78474)
• the genetic background indicates the mouse should be non-agouti black however the dorsal coat is agouti (J:78474)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:78474)
• the ventrum is cream to white not non-agouti black as inferred from the strain background (J:78474)




Genotype
MGI:3760281
ht26
Allelic
Composition
Ay/a
Genetic
Background
involves: KK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• blood glucose levels increase with age in both sexes (J:26460)
• marked hyperglycemia (400-500 mg/dl) develops by 16 weeks of age (J:26460)
• blood glucose levels increase with age in both sexes (J:26460)
• marked hyperglycemia (400-500 mg/dl) develops by 16 weeks of age (J:26460)
• markedly elevated plasma immunoreactive insulin (IRI) level increases with age (J:26460)
• markedly elevated plasma immunoreactive insulin (IRI) level increases with age (J:26460)
• present at all ages tested (5, 10, 16 weeks) and in both sexes (J:26460)
• present at all ages tested (5, 10, 16 weeks) and in both sexes (J:26460)
• insulin sensitivity is impaired at 10 weeks and lost by 16 weeks (J:26460)
• insulin sensitivity is impaired at 10 weeks and lost by 16 weeks (J:26460)
• lipogenesis from acetate is elevated at 5 weeks of age, the enhanced activity is maintained until 16 weeks of age (J:26460)
• the acetate/glucose ratio is higher than control in young mice (J:26460)
• lipogenesis from acetate is elevated at 5 weeks of age, the enhanced activity is maintained until 16 weeks of age (J:26460)
• the acetate/glucose ratio is higher than control in young mice (J:26460)

adipose tissue
• adipose tissue weight increases with age, reaching a maximum at 10 weeks of age (J:26460)
• adipose tissue weight increases with age, reaching a maximum at 10 weeks of age (J:26460)

growth/size/body
• adipose tissue weight increases with age, reaching a maximum at 10 weeks of age (J:26460)
• adipose tissue weight increases with age, reaching a maximum at 10 weeks of age (J:26460)
• greater body weight gain occurs in females as compared to black KK controls (J:26460)
• greater body weight gain occurs in females as compared to black KK controls (J:26460)

endocrine/exocrine glands
• islets are hypertrophic in 10-16 week old mice (J:26460)
• central cavity formation with occasional red blood cells is observed in islets (J:26460)
• islets are hypertrophic in 10-16 week old mice (J:26460)
• central cavity formation with occasional red blood cells is observed in islets (J:26460)
• beta cells are degranulated (J:26460)
• degranulated islets are infiltrated with fine glycogen granules (J:26460)
• beta cells are degranulated (J:26460)
• degranulated islets are infiltrated with fine glycogen granules (J:26460)

renal/urinary system
• present at all ages tested (5, 10, 16 weeks) and in both sexes (J:26460)
• present at all ages tested (5, 10, 16 weeks) and in both sexes (J:26460)
• basement membrane of Bowman's capsules is thickened (J:26460)
• basement membrane of Bowman's capsules is thickened (J:26460)
• some glomeruli exhibit an accumulation of eosinophilic material in the outer parts of the capillary (J:26460)
• some glomeruli exhibit an accumulation of eosinophilic material in the outer parts of the capillary (J:26460)
• mesangial matrix is thickened (J:26460)
• mesangial matrix is thickened (J:26460)
• basement membrane of tubules is thickened (J:26460)
• hyaline materials or hyaline cast is present in tubules (J:26460)
• basement membrane of tubules is thickened (J:26460)
• hyaline materials or hyaline cast is present in tubules (J:26460)
• hyaline materials or hyaline cast is present in tubules (J:26460)
• hyaline materials or hyaline cast is present in tubules (J:26460)

Mouse Models of Human Disease
OMIM ID Ref(s)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM 125853 J:26460




Genotype
MGI:3789002
ht27
Allelic
Composition
Aw/a
Genetic
Background
involves: SM/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw mutation (17 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• total cortex and x-zone of adrenal cortex are of similar thickness to a/a and Aw/ Aw 70-day old virgin mice (J:19308)
• X-zone is composed exclusively of non-vacuolated cells (J:19308)
• 70-day old hybrids of mixed C57BL/6 and SM/J background have non-vacuolated x-zones (J:19308)
• total cortex and x-zone of adrenal cortex are of similar thickness to a/a and Aw/ Aw 70-day old virgin mice (J:19308)
• X-zone is composed exclusively of non-vacuolated cells (J:19308)
• 70-day old hybrids of mixed C57BL/6 and SM/J background have non-vacuolated x-zones (J:19308)




Genotype
MGI:3047806
ht28
Allelic
Composition
ajl10/a
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
ajl10 mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)

integument
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)




Genotype
MGI:3047815
ht29
Allelic
Composition
ajl41/a
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
ajl41 mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)

integument
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)




Genotype
MGI:3047817
ht30
Allelic
Composition
ajl85/a
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
ajl85 mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)

integument
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)
• jet-black appearance is probably equivalent to extreme nonagouti (J:16567)




Genotype
MGI:4367209
ht31
Allelic
Composition
a/atwp
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
atwp mutation (0 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a black dorsum and white ventrum (J:16568)
• mice have a black dorsum and white ventrum (J:16568)
• mice have a white ventrum, the pattern identical to that seen on at/- mice (J:16568)
• mice have a subtle yellow throat patch (J:16568)
• mice have a white ventrum, the pattern identical to that seen on at/- mice (J:16568)
• mice have a subtle yellow throat patch (J:16568)

integument
• mice have a black dorsum and white ventrum (J:16568)
• mice have a black dorsum and white ventrum (J:16568)
• mice have a white ventrum, the pattern identical to that seen on at/- mice (J:16568)
• mice have a subtle yellow throat patch (J:16568)
• mice have a white ventrum, the pattern identical to that seen on at/- mice (J:16568)
• mice have a subtle yellow throat patch (J:16568)




Genotype
MGI:5299236
ht32
Allelic
Composition
a/a20H
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
a20H mutation (1 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• umbrous-like (J:90559)
• umbrous-like (J:90559)

pigmentation
• umbrous-like (J:90559)
• umbrous-like (J:90559)




Genotype
MGI:3805043
cx33
Allelic
Composition
a/a
Hps6ru/Hps6ru
Genetic
Background
B6.Cg-Hps6ru
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Hps6ru mutation (6 available); any Hps6 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• platelet ADP levels are much lower than in C57BL/6J controls (J:7327)
• platelet ADP levels are much lower than in C57BL/6J controls (J:7327)
• platelet ATP levels are much lower than in C57BL/6J controls (J:7327)
• platelet ATP levels are much lower than in C57BL/6J controls (J:7327)
• fewer platelet dense granules than normal (J:7327)
• fewer platelet dense granules than normal (J:7327)
• less than 7% of normal levels of platelet serotonin (J:7327)
• less than 7% of normal levels of platelet serotonin (J:7327)
• platelet serotonin level is also lower than that of control when fed an atherogenic diet (J:29748)
• platelet serotonin level is also lower than that of control when fed an atherogenic diet (J:29748)

homeostasis/metabolism
• less than 7% of normal levels of platelet serotonin (J:7327)
• less than 7% of normal levels of platelet serotonin (J:7327)
• platelet serotonin level is also lower than that of control when fed an atherogenic diet (J:29748)
• platelet serotonin level is also lower than that of control when fed an atherogenic diet (J:29748)
• bleed time averaging over 15 minutes after tail nick is much greater than the 3.8 minutes for C57BL/6J controls (J:7327)
• bleed time averaging over 15 minutes after tail nick is much greater than the 3.8 minutes for C57BL/6J controls (J:7327)

cardiovascular system
• on an atherogenic diet homozygotes develop fewer aortic lesions and smaller lesions than C57BL/6J controls (J:29748)
• 60% of homozygotes survive to 48 weeks of age on an atherogenic diet, when no C57BL/6J controls survive, and, although there are significant atherosclerotic lesions in these 48 week old homozygotes, the lesions are smaller than those in 39 week old C57BL/6J controls fed the atherogenic diet (J:29748)
• on an atherogenic diet homozygotes develop fewer aortic lesions and smaller lesions than C57BL/6J controls (J:29748)
• 60% of homozygotes survive to 48 weeks of age on an atherogenic diet, when no C57BL/6J controls survive, and, although there are significant atherosclerotic lesions in these 48 week old homozygotes, the lesions are smaller than those in 39 week old C57BL/6J controls fed the atherogenic diet (J:29748)

integument

pigmentation

nervous system
• the ipsilateral lateral geniculate nucleus has fewer projections from the retinal ganglion cells (J:6064)
• the ipsilateral lateral geniculate nucleus has fewer projections from the retinal ganglion cells (J:6064)
• there is a reduced number of projections of retinal ganglion cells to the ipsilateral lateral geniculate nucleus (J:6064)
• there is a reduced number of projections of retinal ganglion cells to the ipsilateral lateral geniculate nucleus (J:6064)

vision/eye
• there is a reduced number of projections of retinal ganglion cells to the ipsilateral lateral geniculate nucleus (J:6064)
• there is a reduced number of projections of retinal ganglion cells to the ipsilateral lateral geniculate nucleus (J:6064)

renal/urinary system
• concentration of lysosomal enzymes is elevated (J:6422)
• decreased rate of secretion of lysosomal enzyme into urine (J:6422)
• concentration of lysosomal enzymes is elevated (J:6422)
• decreased rate of secretion of lysosomal enzyme into urine (J:6422)




Genotype
MGI:5609871
cx34
Allelic
Composition
Ay/a
Sik2tm1Htake/Sik2+
Genetic
Background
C57BL/6-Sik2tm1Htake
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Sik2tm1Htake mutation (0 available); any Sik2 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• slightly darker than in Ay/a mice on the dorsal region (J:215877)
• darker ventral region hair compared with Ay/a mice (J:215877)
• slightly darker than in Ay/a mice on the dorsal region (J:215877)
• darker ventral region hair compared with Ay/a mice (J:215877)

pigmentation
• slightly darker than in Ay/a mice on the dorsal region (J:215877)
• darker ventral region hair compared with Ay/a mice (J:215877)
• slightly darker than in Ay/a mice on the dorsal region (J:215877)
• darker ventral region hair compared with Ay/a mice (J:215877)




Genotype
MGI:3813609
cx35
Allelic
Composition
a/a
KitW-2J/Kit+
Genetic
Background
C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
KitW-2J mutation (5 available); any Kit mutation (113 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• about 75% of the coat is pigmented on this background (J:192797)
• about 75% of the coat is pigmented on this background (J:192797)

integument
• about 75% of the coat is pigmented on this background (J:192797)
• about 75% of the coat is pigmented on this background (J:192797)




Genotype
MGI:3052536
cx36
Allelic
Composition
a/a
Mlphln/Mlphln
Tyrp1b/Tyrp1b
Genetic
Background
C57L/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mlphln mutation (14 available); any Mlph mutation (20 available)
Tyrp1b mutation (97 available); any Tyrp1 mutation (152 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• due to clumping of pigment (J:5095)
• due to clumping of pigment (J:5095)
• results in clumping rather than even distribution of pigment during hair development (J:5095)
• results in clumping rather than even distribution of pigment during hair development (J:5095)

integument
• due to clumping of pigment (J:5095)
• due to clumping of pigment (J:5095)




Genotype
MGI:5636497
cx37
Allelic
Composition
a/a
Pax3Sp-1H/Pax3Sp-1H
Genetic
Background
involves: 101/H * C3H/HeH * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Pax3Sp-1H mutation (1 available); any Pax3 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryogenesis
• in half of E13.5 embryos examined, parts of the rostral neural tube are not closed properly (J:19818)
• in half of E13.5 embryos examined, parts of the rostral neural tube are not closed properly (J:19818)

nervous system
• in half of E13.5 embryos examined, parts of the rostral neural tube are not closed properly (J:19818)
• in half of E13.5 embryos examined, parts of the rostral neural tube are not closed properly (J:19818)
• in some mutants the rostral nueral tube does not close leaving the hindbrain, midbrain, and most of the forebrain exposed (J:19818)
• in some mutants the rostral nueral tube does not close leaving the hindbrain, midbrain, and most of the forebrain exposed (J:19818)
• incomplete closure of anterior neuropore leads to collapse of lateral ventricles (J:19818)
• incomplete closure of anterior neuropore leads to collapse of lateral ventricles (J:19818)
• noted in lateral ventricles of E16.5 fetuses (J:19818)
• noted in lateral ventricles of E16.5 fetuses (J:19818)
• E16.5 fetuses do not show lamination in the cerebral cortex (J:19818)
• E16.5 fetuses do not show lamination in the cerebral cortex (J:19818)
• noted at E16.5 of gestation (J:19818)
• noted at E16.5 of gestation (J:19818)




Genotype
MGI:3526898
cx38
Allelic
Composition
Ay/a
Npbwr1tm1Rck/Npbwr1tm1Rck
Genetic
Background
involves: 129P/Ola * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Npbwr1tm1Rck mutation (0 available); any Npbwr1 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• male double homozygotes were more obese than heterozygous Ay males whereas females weighted the same as heterozygous Ay females (J:94820)
• male double homozygotes were more obese than heterozygous Ay males whereas females weighted the same as heterozygous Ay females (J:94820)




Genotype
MGI:5297860
cx39
Allelic
Composition
Ay/a
Apoetm1Unc/Apoetm1Unc
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Apoetm1Unc mutation (22 available); any Apoe mutation (64 available)
Ay mutation (10 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• mutants develop larger atherosclerotic plaques than a/a Apoetm1Unc/Apoetm1Unc mice (J:177084)
• plaques contain a higher proportion of macrophage infiltration (J:177084)
• mutants develop larger atherosclerotic plaques than a/a Apoetm1Unc/Apoetm1Unc mice (J:177084)
• plaques contain a higher proportion of macrophage infiltration (J:177084)

growth/size/body
• mutants exhibit increased weight gain, despite similar food intake as controls (J:177084)
• mutants exhibit increased weight gain, despite similar food intake as controls (J:177084)

hematopoietic system
• increase in the proportion of inflammatory monocytes in the blood, liver, muscle, and kidney, but not epididymal fat pads (J:177084)
• increase in the proportion of inflammatory monocytes in the blood, liver, muscle, and kidney, but not epididymal fat pads (J:177084)

homeostasis/metabolism

immune system
• increase in the proportion of inflammatory monocytes in the blood, liver, muscle, and kidney, but not epididymal fat pads (J:177084)
• increase in the proportion of inflammatory monocytes in the blood, liver, muscle, and kidney, but not epididymal fat pads (J:177084)
• increase in systemic inflammation (J:177084)
• increase in systemic inflammation (J:177084)

renal/urinary system
• mutants develop features of diabetic nephropathy (J:177084)
• mutants develop features of diabetic nephropathy (J:177084)
• mutants exhibit mesangial expansion as indicated by glycogen deposition in the glomeruli (J:177084)
• mutants exhibit mesangial expansion as indicated by glycogen deposition in the glomeruli (J:177084)
• 20-30% of mutants exhibit nodular sclerosis in the kidney (J:177084)
• 20-30% of mutants exhibit nodular sclerosis in the kidney (J:177084)




Genotype
MGI:5297861
cx40
Allelic
Composition
Ay/a
Apoetm1Unc/Apoetm1Unc
Ccr2tm1Mae/Ccr2tm1Mae
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Apoetm1Unc mutation (22 available); any Apoe mutation (64 available)
Ay mutation (10 available); any a mutation (350 available)
Ccr2tm1Mae mutation (2 available); any Ccr2 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mutants are protected against the metabolic syndrome, atherosclerosis, and diabetic nephropathy that develops in Ay/a Apoetm1Unc double mutants (J:177084)
• mutants are protected against the metabolic syndrome, atherosclerosis, and diabetic nephropathy that develops in Ay/a Apoetm1Unc double mutants (J:177084)




Genotype
MGI:3778273
cx41
Allelic
Composition
Avy/a
Axin1Fu/Axin1+
Genetic
Background
involves: 129P4/RrRk * C67BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Avy mutation (7 available); any a mutation (350 available)
Axin1Fu mutation (1 available); any Axin1 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• penetrance of fused and viable yellow are independent of each other with double heterozygotes displaying all combinations of coat color and tail phenotypes due to independent variations in penetrance of each (J:82396)
• penetrance of fused and viable yellow are independent of each other with double heterozygotes displaying all combinations of coat color and tail phenotypes due to independent variations in penetrance of each (J:82396)




Genotype
MGI:3776093
cx42
Allelic
Composition
Ay/a
Agrptm2(DTR)Rpa/Agrp+
Genetic
Background
involves: 129S4/SvJaeSor * KK/Upj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Agrptm2(DTR)Rpa mutation (0 available); any Agrp mutation (2 available)
Ay mutation (10 available); any a mutation (350 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in mice treated with diptheria toxin (DT) to specifically ablate NPY-expressing cells (J:132184)
• in mice treated with diptheria toxin (DT) to specifically ablate NPY-expressing cells (J:132184)

growth/size/body
• in mice treated with diptheria toxin (DT) to specifically ablate NPY-expressing cells (J:132184)
• in mice treated with diptheria toxin (DT) to specifically ablate NPY-expressing cells (J:132184)




Genotype
MGI:3805940
cx43
Allelic
Composition
a/A
Pomctm1Sora/Pomctm1Sora
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
A mutation (33 available); any a mutation (350 available)
Pomctm1Sora mutation (0 available); any Pomc mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a slightly more yellow coat than agouti controls (J:129904)
• mice have a slightly more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (0.30) than in agouti controls (0.19) (J:129904)
• the phaeomelanin to total melanin ratio is higher (0.30) than in agouti controls (0.19) (J:129904)

integument
• mice have a slightly more yellow coat than agouti controls (J:129904)
• mice have a slightly more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (0.30) than in agouti controls (0.19) (J:129904)
• the phaeomelanin to total melanin ratio is higher (0.30) than in agouti controls (0.19) (J:129904)




Genotype
MGI:3805942
cx44
Allelic
Composition
a/A
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6Ha
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
A mutation (33 available); any a mutation (350 available)
Mc1re mutation (6 available); any Mc1r mutation (17 available)
Pomctm1Sora mutation (0 available); any Pomc mutation (8 available)
Tg(MC1R)1Jkn mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a much more yellow coat than agouti controls (J:129904)
• mice have a much more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19) (J:129904)
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19) (J:129904)

integument
• mice have a much more yellow coat than agouti controls (J:129904)
• mice have a much more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19) (J:129904)
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19) (J:129904)




Genotype
MGI:3805943
cx45
Allelic
Composition
a/a
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6Ha
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mc1re mutation (6 available); any Mc1r mutation (17 available)
Pomctm1Sora mutation (0 available); any Pomc mutation (8 available)
Tg(MC1R)1Jkn mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a much more yellow coat than agouti controls (J:129904)
• mice have a much more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20) (J:129904)
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20) (J:129904)

integument
• mice have a much more yellow coat than agouti controls (J:129904)
• mice have a much more yellow coat than agouti controls (J:129904)
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20) (J:129904)
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20) (J:129904)




Genotype
MGI:3772887
cx46
Allelic
Composition
Aw/a
Corintm1Bamo/Corintm1Bamo
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Aw mutation (17 available); any a mutation (350 available)
Corintm1Bamo mutation (0 available); any Corin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele (J:130426)
• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)
• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele (J:130426)
• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)

integument
• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele (J:130426)
• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)
• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele (J:130426)
• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)




Genotype
MGI:3772889
cx47
Allelic
Composition
a/a
Corintm1Bamo/Corintm1Bamo
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Corintm1Bamo mutation (0 available); any Corin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
N
• mice exhibit normal black coat color (J:130426)
• Background Sensitivity: authors state that mice on a C57BL/6 background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)
• mice exhibit normal black coat color (J:130426)
• Background Sensitivity: authors state that mice on a C57BL/6 background for more than 6 generation exhibit a qualitatively similar phenotype (J:130426)




Genotype
MGI:4454423
cx48
Allelic
Composition
a/a
Oca2p-J/Oca2p-J
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Oca2p-J mutation (4 available); any Oca2 mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 20% of melanosomes in adult retina are fibrillar in nature, the rest are particulate (J:5346)
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 20% of melanosomes in adult retina are fibrillar in nature, the rest are particulate (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)
• premature termination of melanization of the premelanosome filaments in the retina (J:5346)
• premature termination of melanization of the premelanosome filaments in the retina (J:5346)

vision/eye
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)




Genotype
MGI:4454430
cx49
Allelic
Composition
a/a
Lystbg/Lystbg
Oca2p-J/Oca2p-J
Genetic
Background
involves: C3H/HeJ * C3H/Rl * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Lystbg mutation (5 available); any Lyst mutation (47 available)
Oca2p-J mutation (4 available); any Oca2 mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 35% of melanosomes in adult retina are fibrillar in nature, the rest are particulate (J:5346)
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 35% of melanosomes in adult retina are fibrillar in nature, the rest are particulate (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)

vision/eye
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)
• 2% of premelanosomes in the choroid are fused to form giant granules (J:5346)




Genotype
MGI:5505784
cx50
Allelic
Composition
a/a
Rab27aash/Rab27aash
Genetic
Background
involves: C3H/HeSnJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Rab27aash mutation (3 available); any Rab27a mutation (128 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• Background Sensitivity: platelet-dense granules and platelet coagulation are normal or near normal unlike on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: concentrations of adenine nucleotides, ADP and ATP, of platelets are only nominally lower than controls and are not significantly different from controls compared to on the C3H/HeSnJ background where levels are depressed (J:77395)
• Background Sensitivity: platelet-dense granules and platelet coagulation are normal or near normal unlike on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: concentrations of adenine nucleotides, ADP and ATP, of platelets are only nominally lower than controls and are not significantly different from controls compared to on the C3H/HeSnJ background where levels are depressed (J:77395)
• Background Sensitivity: platelet-dense granule serotonin levels are somewhat depressed in platelets compared to wild-type, but levels are much greater than on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: platelet-dense granule serotonin levels are somewhat depressed in platelets compared to wild-type, but levels are much greater than on the C3H/HeSnJ background (J:77395)

homeostasis/metabolism
• Background Sensitivity: platelet-dense granule serotonin levels are somewhat depressed in platelets compared to wild-type, but levels are much greater than on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: platelet-dense granule serotonin levels are somewhat depressed in platelets compared to wild-type, but levels are much greater than on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: modest increase in bleeding time to 6.9 minutes from the normal 2.7 minutes, but shorter than on the C3H/HeSnJ background (J:77395)
• Background Sensitivity: modest increase in bleeding time to 6.9 minutes from the normal 2.7 minutes, but shorter than on the C3H/HeSnJ background (J:77395)

Mouse Models of Human Disease
OMIM ID Ref(s)
Griscelli Syndrome, Type 2; GS2 607624 J:77395




Genotype
MGI:4454426
cx51
Allelic
Composition
a/a
Lystbg/Lystbg
Genetic
Background
involves: C3H/Rl * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Lystbg mutation (5 available); any Lyst mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• 80% of premelanosomes in the choroid and retina are fused to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina are fused to form giant granules (J:5346)
• 80% of premelanosomes in the retina and choroid are fused to form giant granules (J:5346)
• 80% of premelanosomes in the retina and choroid are fused to form giant granules (J:5346)

vision/eye
• 80% of premelanosomes in the choroid and retina are fused to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina are fused to form giant granules (J:5346)
• 80% of premelanosomes in the retina and choroid are fused to form giant granules (J:5346)
• 80% of premelanosomes in the retina and choroid are fused to form giant granules (J:5346)




Genotype
MGI:4454429
cx52
Allelic
Composition
a/a
Lystbg/Lystbg
Tyrc/Tyrc
Genetic
Background
involves: C3H/Rl * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Lystbg mutation (5 available); any Lyst mutation (47 available)
Tyrc mutation (138 available); any Tyr mutation (348 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• absence of fibrillar melanosomes in the choroid and retina (J:5346)
• absence of fibrillar melanosomes in the choroid and retina (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• absence of melanin deposition on premelanosome filaments (J:5346)
• absence of melanin deposition on premelanosome filaments (J:5346)

vision/eye
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)
• number of granules diminishes in adults after birth (J:5346)




Genotype
MGI:4454431
cx53
Allelic
Composition
a/a
Hps6ru/Hps6ru
Lystbg/Lystbg
Genetic
Background
involves: C3H/Rl * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Hps6ru mutation (6 available); any Hps6 mutation (8 available)
Lystbg mutation (5 available); any Lyst mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 5% of melanosomes in the choroid and 60% in the retina are fibrillar in nature, the rest are particulate (J:5346)
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 5% of melanosomes in the choroid and 60% in the retina are fibrillar in nature, the rest are particulate (J:5346)
• 80% of premelanosomes in the retina are fused to form giant premelanosomes (J:5346)
• 80% of premelanosomes in the retina are fused to form giant premelanosomes (J:5346)
• premelanosome formation in the choroid is delayed until after birth (J:5346)
• premelanosome formation in the choroid is delayed until after birth (J:5346)

vision/eye
• 80% of premelanosomes in the retina are fused to form giant premelanosomes (J:5346)
• 80% of premelanosomes in the retina are fused to form giant premelanosomes (J:5346)




Genotype
MGI:4454432
cx54
Allelic
Composition
a/a
Lystbg/Lystbg
Tyrp1b/Tyrp1b
Genetic
Background
involves: C3H/Rl * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Lystbg mutation (5 available); any Lyst mutation (47 available)
Tyrp1b mutation (97 available); any Tyrp1 mutation (152 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)

vision/eye
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)
• 80% of premelanosomes in the choroid and retina fuse to form giant granules (J:5346)




Genotype
MGI:4936833
cx55
Allelic
Composition
Ay/a
Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic
Background
involves: C57BL/6 * KK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Rmi1Gt(pUHachi)0283Imeg mutation (0 available); any Rmi1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)

homeostasis/metabolism
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)

behavior/neurological
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)

liver/biliary system
• compared with Ay/a mice (J:168271)
• compared with Ay/a mice (J:168271)

adipose tissue
N
• mice exhibit normal intra-abdominal fat (J:168271)
• mice exhibit normal intra-abdominal fat (J:168271)




Genotype
MGI:4936834
cx56
Allelic
Composition
a/a
Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic
Background
involves: C57BL/6 * KK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Rmi1Gt(pUHachi)0283Imeg mutation (0 available); any Rmi1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)

homeostasis/metabolism
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)

liver/biliary system
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)

adipose tissue
• compared with a/a homozygotes (J:168271)
• compared with a/a homozygotes (J:168271)

behavior/neurological
N
• mice exhibit normal food intake (J:168271)
• mice exhibit normal food intake (J:168271)




Genotype
MGI:4454419
cx57
Allelic
Composition
a/a
Tyrc/Tyrc
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Tyrc mutation (138 available); any Tyr mutation (348 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• premelanosomes form normally but melanin is not deposited on the filaments and they never mature and eventually disappear in the retina (J:5346)
• premelanosomes form normally but melanin is not deposited on the filaments and they never mature and eventually disappear in the retina (J:5346)




Genotype
MGI:4454424
cx58
Allelic
Composition
a/a
Hps6ru/Hps6ru
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Hps6ru mutation (6 available); any Hps6 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 5% of melanosomes in the choroid and 50% in the retina are fibrillar in nature, the rest are particulate (J:5346)
• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 5% of melanosomes in the choroid and 50% in the retina are fibrillar in nature, the rest are particulate (J:5346)
• premelanosome formation and the subsequent deposition of melanin in the choroid is delayed until after birth (J:5346)
• decrease in the melanization of pigment granules (J:5346)
• premelanosome formation and the subsequent deposition of melanin in the choroid is delayed until after birth (J:5346)
• decrease in the melanization of pigment granules (J:5346)

vision/eye




Genotype
MGI:4454425
cx59
Allelic
Composition
a/a
Tyrp1b/Tyrp1b
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Tyrp1b mutation (97 available); any Tyrp1 mutation (152 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• reorganization of fibrillar melanosomes into particulate melanin granules, such that 20% of granules in the choroid are particulate (J:5346)
• reorganization of fibrillar melanosomes into particulate melanin granules, such that 20% of granules in the choroid are particulate (J:5346)




Genotype
MGI:4454434
cx60
Allelic
Composition
a/a
Bloc1s6pa/Bloc1s6pa
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Bloc1s6pa mutation (11 available); any Bloc1s6 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• number of granules in the retina is greatly reduced (J:5346)
• size of granules is diminished (J:5346)
• number of granules in the retina is greatly reduced (J:5346)
• size of granules is diminished (J:5346)

vision/eye
• number of granules in the retina is greatly reduced (J:5346)
• size of granules is diminished (J:5346)
• number of granules in the retina is greatly reduced (J:5346)
• size of granules is diminished (J:5346)




Genotype
MGI:5466757
cx61
Allelic
Composition
a/a
Mregdsu/Mregdsu
Hps6ru/Hps6ru
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Hps6ru mutation (6 available); any Hps6 mutation (8 available)
Mregdsu mutation (1 available); any Mreg mutation (94 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• products of this genotype normalize eye color from ruby to wild-type black (J:29467)
• coat color dilution is not affected (J:29467)
• products of this genotype normalize eye color from ruby to wild-type black (J:29467)
• coat color dilution is not affected (J:29467)

integument
• coat color dilution is not affected by the dilute repressor mutation, Mregdsu (J:29467)
• the wild-type nonagouti black coat is diluted to a dull reddish brown (J:29467)
• coat color dilution is not affected by the dilute repressor mutation, Mregdsu (J:29467)
• the wild-type nonagouti black coat is diluted to a dull reddish brown (J:29467)

pigmentation
• coat color dilution is not affected by the dilute repressor mutation, Mregdsu (J:29467)
• the wild-type nonagouti black coat is diluted to a dull reddish brown (J:29467)
• coat color dilution is not affected by the dilute repressor mutation, Mregdsu (J:29467)
• the wild-type nonagouti black coat is diluted to a dull reddish brown (J:29467)




Genotype
MGI:2175418
cx62
Allelic
Composition
a/a
Zc3h4KK/Zc3h4KK
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Zc3h4KK mutation (0 available); any Zc3h4 mutation (138 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body




Genotype
MGI:2679980
cx63
Allelic
Composition
a/Ay
Zc3h4KK/Zc3h4KK
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Zc3h4KK mutation (0 available); any Zc3h4 mutation (138 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body




Genotype
MGI:2679981
cx64
Allelic
Composition
a/Ay
Zc3h4C57BL/6J/Zc3h4KK
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Zc3h4C57BL/6J mutation (0 available); any Zc3h4 mutation (138 available)
Zc3h4KK mutation (0 available); any Zc3h4 mutation (138 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased body weight (J:48704)
• increased body weight (J:48704)




Genotype
MGI:3487268
cx65
Allelic
Composition
a/Ay
Bwq2KK/Bwq2KK
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Bwq2KK mutation (0 available); any Bwq2 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased body weight at 40-100 days of age (J:93199)
• increased body weight at 40-100 days of age (J:93199)
• increased body weight at 40, 50, and 60 days of age (J:131439)
• increased body weight at 40, 50, and 60 days of age (J:131439)
• increased weight gain at 30-40 days of age (J:93199)
• increased weight gain at 30-40 days of age (J:93199)




Genotype
MGI:3773901
cx66
Allelic
Composition
a/Ay
Bwq10C57BL/6J/Bwq10C57BL/6J
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Bwq10C57BL/6J mutation (0 available); any Bwq10 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased body weight at 40, 50, and 60 days of age (J:131439)
• increased body weight at 40, 50, and 60 days of age (J:131439)




Genotype
MGI:3773902
cx67
Allelic
Composition
a/Ay
Guq1KK/Guq1KK
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Guq1KK mutation (0 available); any Guq1 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased glucosuria severity at 40 days of age (J:131439)
• increased glucosuria severity at 40 days of age (J:131439)

renal/urinary system
• increased glucosuria severity at 40 days of age (J:131439)
• increased glucosuria severity at 40 days of age (J:131439)




Genotype
MGI:3773903
cx68
Allelic
Composition
a/Ay
Guq2C57BL/6J/Guq2C57BL/6J
Genetic
Background
involves: C57BL/6J * KK-Ay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Guq2C57BL/6J mutation (0 available); any Guq2 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased glucosuria severity at 40 days of age (J:131439)
• increased glucosuria severity at 40 days of age (J:131439)

renal/urinary system
• increased glucosuria severity at 40 days of age (J:131439)
• increased glucosuria severity at 40 days of age (J:131439)




Genotype
MGI:3833436
cx69
Allelic
Composition
Ay/a
Mssq1KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq1KK/TaJcl mutation (0 available); any Mssq1 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833437
cx70
Allelic
Composition
a/a
Mssq1KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq1KK/TaJcl mutation (0 available); any Mssq1 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833439
cx71
Allelic
Composition
Ay/a
Mssq2C57BL/6JJcl/Mssq2KK/TaJcl
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq2C57BL/6JJcl mutation (0 available); any Mssq2 mutation (0 available)
Mssq2KK/TaJcl mutation (0 available); any Mssq2 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833448
cx72
Allelic
Composition
Ay/a
Mssq3KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq3KK/TaJcl mutation (0 available); any Mssq3 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833451
cx73
Allelic
Composition
a/a
Mssq3KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq3KK/TaJcl mutation (0 available); any Mssq3 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833452
cx74
Allelic
Composition
Ay/a
Mssq4KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq4KK/TaJcl mutation (0 available); any Mssq4 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833453
cx75
Allelic
Composition
a/a
Mssq4KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq4KK/TaJcl mutation (0 available); any Mssq4 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833454
cx76
Allelic
Composition
Ay/a
Mssq5C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq5C57BL/6JJcl mutation (0 available); any Mssq5 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833455
cx77
Allelic
Composition
a/a
Mssq5C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq5C57BL/6JJcl mutation (0 available); any Mssq5 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833456
cx78
Allelic
Composition
Ay/a
Mssq6C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq6C57BL/6JJcl mutation (0 available); any Mssq6 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased values for principal component analysis of mandible size (J:143893)
• increased values for principal component analysis of mandible size (J:143893)

skeleton
• increased values for principal component analysis of mandible size (J:143893)
• increased values for principal component analysis of mandible size (J:143893)




Genotype
MGI:3833457
cx79
Allelic
Composition
a/a
Mssq6C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq6C57BL/6JJcl mutation (0 available); any Mssq6 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased values for pricipal component analysis of mandible size (J:143893)
• increased values for pricipal component analysis of mandible size (J:143893)

skeleton
• increased values for pricipal component analysis of mandible size (J:143893)
• increased values for pricipal component analysis of mandible size (J:143893)




Genotype
MGI:3833460
cx80
Allelic
Composition
Ay/a
Mssq6KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq6KK/TaJcl mutation (0 available); any Mssq6 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833461
cx81
Allelic
Composition
a/a
Mssq6KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq6KK/TaJcl mutation (0 available); any Mssq6 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833471
cx82
Allelic
Composition
Ay/a
Mssq7KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq7KK/TaJcl mutation (0 available); any Mssq7 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833472
cx83
Allelic
Composition
a/a
Mssq7KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq7KK/TaJcl mutation (0 available); any Mssq7 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833967
cx84
Allelic
Composition
a/a
Mssq8C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq8C57BL/6JJcl mutation (0 available); any Mssq8 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased values for principal component analysis of mandible size (J:143893)
• increased values for principal component analysis of mandible size (J:143893)

skeleton
• increased values for principal component analysis of mandible size (J:143893)
• increased values for principal component analysis of mandible size (J:143893)




Genotype
MGI:3833968
cx85
Allelic
Composition
a/a
Mssq9C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq9C57BL/6JJcl mutation (0 available); any Mssq9 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833969
cx86
Allelic
Composition
Ay/a
Mssq9C57BL/6JJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq9C57BL/6JJcl mutation (0 available); any Mssq9 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833970
cx87
Allelic
Composition
a/a
Mssq10KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq10KK/TaJcl mutation (0 available); any Mssq10 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833971
cx88
Allelic
Composition
Ay/a
Mssq10KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Ay mutation (10 available); any a mutation (350 available)
Mssq10KK/TaJcl mutation (0 available); any Mssq10 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased mandible size (J:143893)
• increased mandible size (J:143893)

skeleton
• increased mandible size (J:143893)
• increased mandible size (J:143893)




Genotype
MGI:3833972
cx89
Allelic
Composition
a/a
Mssq11KK/TaJcl/?
Genetic
Background
involves: C57BL/6JJcl * KK/TaJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (178 available); any a mutation (350 available)
Mssq11KK/TaJcl mutation (0 available); any Mssq11 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• increased values for principal component analysis of mandible size measurements (J:143893)
• increased values for principal component analysis of mandible size measurements (J:143893)

skeleton
• increased values for principal component analysis of mandible size measurements (J:143893)
• increased values for principal component analysis of mandible size measurements (J:143893)




Genotype
MGI:3833973
cx90
Allelic
Composition