About   Help   FAQ
Boc Gene Detail
Summary
  • Symbol
    Boc
  • Name
    BOC cell adhesion associated, oncogene regulated
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151153
    NCBI Gene: 117606
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:44305408-44379233 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 28.81 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2120 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151153
 protein coding gene Chr16:44305408-44379260 (-)
129S1/SvImJ ENSMUSG00200021122
 protein coding gene Chr16:41202399-41276170 (-)
A/J ENSMUSG00195003296
 protein coding gene Chr16:40781976-40855887 (-)
AKR/J ENSMUSG00220021710
 protein coding gene Chr16:41117415-41191341 (-)
BALB/cJ ENSMUSG00180025486
 protein coding gene Chr16:40988430-41062353 (-)
C3H/HeJ ENSMUSG00175024050
 protein coding gene Chr16:41264414-41338236 (-)
C57BL/6NJ ENSMUSG00215005994
 protein coding gene Chr16:41085462-41159359 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020768
 protein coding gene Chr16:41345361-41420824 (-)
CAST/EiJ ENSTCUG00005012384
 protein coding gene Chr16:41515522-41590481 (-)
CBA/J ENSMUSG00210016650
 protein coding gene Chr16:41287160-41360972 (-)
DBA/2J ENSMUSG00185010824
 protein coding gene Chr16:41168140-41242061 (-)
FVB/NJ ENSMUSG00205012029
 protein coding gene Chr16:41118896-41192655 (-)
JF1/MsJ ENSUMUG00000024464
 protein coding gene Chr16:41389121-41463868 (-)
LP/J ENSMUSG00230025379
 protein coding gene Chr16:43756400-43830169 (-)
NOD/ShiLtJ ENSMUSG00190018492
 protein coding gene Chr16:41296150-41369905 (-)
NZO/HlLtJ ENSMUSG00225028210
 protein coding gene Chr16:46847973-46921795 (-)
PWK/PhJ ENSLUMG00010026180
 protein coding gene Chr16:41287746-41362268 (-)
SPRET/EiJ ENSMSPG00010007085
 protein coding gene Chr16:41347687-41422588 (-)
WSB/EiJ ENSIUOG00005013148
 protein coding gene Chr16:41400045-41473980 (-)



Homology
more
  • Human Ortholog
    BOC, BOC cell adhesion associated, oncogene regulated
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BOC, BOC cell adhesion associated, oncogene regulated
  • Synonyms
    Boi, CDON2
  • Links
    NCBI Gene ID: 91653
    UniProt: Q9BWV1

  • Chr Location
    3q13.2; chr3:113210846-113287463 (+)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 4 alleles in 6 genetic backgrounds
    39 phenotypes from multigenic genotypes
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display abnormal commissural axon projections.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1180
  • Tissues
    340
  • cDNA Data
    70
  • Literature Summary
    43
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 117606 NCBI Gene Model | MGI Sequence Detail 73826 C57BL/6J ±  kb
    transcript NM_172506 RefSeq | MGI Sequence Detail 4428 C57BL/6  
    polypeptide Q6AZB0 UniProt | EBI | MGI Sequence Detail 1110 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 80
      cDNA 71
      Primer pair 3
      Other 6
      Antibodies 2

      Microarray probesets 5
    References
    more
    • Summaries
      All 98
      Developmental Gene Expression 43
      Diseases 1
      Gene Ontology 13
      Phenotypes 36
    • Earliest
      J:72468 Kang JS, et al., BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation. EMBO J. 2002 Jan 15;21(1-2):114-24
    • Latest
      J:386380 Krueger MR, et al., Roles of sonic hedgehog signaling in retinal patterning and neurogenesis during mammalian eye development. Development. 2026 May 1;153(9):dev205143
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory