Sequence Detail

ID/Version

Q6AZB0 Q923W7 Q6KAM5 Q8CE91 Q6P5H3 Q8CE73 Q7TMJ3 Q8R377 (UniProt | EBI)

Last sequence update: 2006-05-02
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Brother of CDO {ECO:0000303|PubMed:11782431}; Short=Protein BOC {ECO:0000303|PubMed:11782431};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1110 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Boc	BOC cell adhesion associated, oncogene regulated	25	121	3	10

Sequence references in MGI

J:72468 Kang JS, et al., BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation. EMBO J. 2002 Jan 15;21(1-2):114-24
J:92574 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Apr 30;11(2):127-35
J:94846 Kang JS, et al., Netrins and neogenin promote myotube formation. J Cell Biol. 2004 Nov 8;167(3):493-504
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108746 Zhang W, et al., Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly. Dev Cell. 2006 May;10(5):657-65
J:108747 Tenzen T, et al., The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. Dev Cell. 2006 May;10(5):647-56
J:115577 Okada A, et al., Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature. 2006 Nov 16;444(7117):369-73
J:173604 Allen BL, et al., Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function. Dev Cell. 2011 Jun 14;20(6):775-87
J:382884 Wierbowski BM, et al., Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. Dev Cell. 2020 Nov 23;55(4):450-467.e8