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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lhx2
LIM homeobox protein 2
MGI:96785
33 phenotypes from 7 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.2Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Yql/Emx1+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cerebral cortex morphology J:130167
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal cerebral cortex morphology J:130167
abnormal telencephalon development J:130167
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		normal nervous system phenotype J:154611
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal neocortex morphology J:154611
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
involves: 129P2/OlaHsd 		normal vision/eye phenotype J:176341
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
Tg(Lhx2-cre)1Lcar/0
involves: 129P2/OlaHsd 		abnormal optic vesicle formation J:176341
anophthalmia J:176341
Lhx2tm1.1Lcar/Lhx2tm1Dra
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1.1Monu/Lhx2tm1.1Monu
involves: 129P2/OlaHsd 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Dra/Lhx2tm1.1Monu
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Dra/Lhx2tm1Dra
involves: 129S4/SvJae 		abnormal basal ganglion morphology J:64676
abnormal cerebral cortex morphology J:64676
abnormal cortical plate morphology J:64676
abnormal erythropoiesis J:64676
abnormal eye development J:64676
abnormal neocortex morphology J:64676
abnormal olfactory bulb morphology J:123232
abnormal optic vesicle formation J:64676
abnormal telencephalon morphology J:64676
absent hippocampus J:64676
absent optic placodes J:64676
absent retina J:64676
anemia J:64676
anophthalmia J:64676
aphakia J:64676
decreased erythroid progenitor cell number J:64676
decreased hematocrit J:64676
flat forehead J:64676
forebrain hypoplasia J:64676
hydrops fetalis J:64676
lethality throughout fetal growth and development, complete penetrance J:64676
liver hypoplasia J:64676
pallor J:64676
small liver J:64676
Lhx2tm1Dra/Lhx2tm1Dra
involves: 129S4/SvJae * C57BL/6 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Lcar/Lhx2tm1Lcar
involves: 129/Sv * C57BL/6 		anemia J:159209
anophthalmia J:159209
decreased hair follicle number J:159209
underdeveloped hair follicles J:159209
Lhx2tm1Monu/Lhx2tm1Dra
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1Monu/Lhx2tm1Monu
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1Monu/Lhx2tm1Monu
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * CD-1 * FVB/N 		abnormal cerebral cortex morphology J:130167
abnormal telencephalon development J:130167
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory