51 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctnnb1tm1Mmt/Ctnnb1+ Krt19tm1(cre)Mmt/Krt19+ involves: 129X1/SvJ	increased intestinal adenoma incidence	J:58367
	premature death	J:58367
Flt4tm1Ali/Flt4tm2.1Ali Krt19tm1(cre)Mmt/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL	abnormal blood vessel morphology	J:137909
	embryonic lethality during organogenesis, complete penetrance	J:137909
Gt(ROSA)26Sortm1(Neurog3*S183A*S187A)Axbe/? Krt19tm1(cre/ERT)Ggu/? B6.Cg-Gt(ROSA)26Sortm1(Neurog3*S183A*S187A)Axbe Krt19tm1(cre/ERT)Ggu	increased pancreatic beta cell number	J:215154
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Krt19tm1(cre/ERT)Ggu/Krt19+ involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac	increased carcinoma incidence	J:172048
	increased gastrointestinal tumor incidence	J:172048
	increased skin tumor incidence	J:172048
	lethality, complete penetrance	J:172048
Krastm4Tyj/Kras+ Krt19tm1(cre/ERT)Ggu/Krt19+ involves: 129S4/SvJae * 129S6/SvEvTac	abnormal skin sebaceous gland morphology	J:172048
	enlarged sebaceous gland	J:172048
	increased cell proliferation	J:172048
	increased hair follicle cell proliferation	J:172048
	increased lip tumor incidence	J:172048
	increased skin papilloma incidence	J:172048
	increased skin tumor incidence	J:172048
	sebaceous gland hyperplasia	J:172048
Krastm4Tyj/Kras+ Krt19tm1(cre/ERT)Ggu/Krt19+ Ptentm2Mak/Ptentm2Mak involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac	abnormal colon morphology	J:254370
	abnormal cystic duct morphology	J:254370
	abnormal extrahepatic bile duct morphology	J:254370
	abnormal gallbladder morphology	J:254370
	abnormal liver morphology	J:254370
	bronchial epithelial hyperplasia	J:254370
	dilated gallbladder	J:254370
	increased pancreatic intraepithelial neoplasia incidence	J:254370
	lung inflammation	J:254370
	premature death	J:254370
	respiratory failure	J:254370
	stomach mucosa hyperplasia	J:254370
Krt18tm1Tmm/Krt18tm1Tmm Krt19tm2Mmt/Krt19tm2Mmt involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * FVB/N	abnormal extraembryonic tissue morphology	J:65090
	abnormal trophoblast giant cell morphology	J:65090
	decreased embryo size	J:65090
	embryonic lethality during organogenesis, complete penetrance	J:65090
	small placenta	J:65090
Krt19tm2Mmt/Krt19tm2Mmt Krt8tm1Rgo/Krt8tm1Rgo FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo	abnormal allantois morphology	J:65498
	abnormal placenta labyrinth morphology	J:65498
	abnormal placenta morphology	J:65498
	abnormal placental labyrinth vasculature morphology	J:65498
	abnormal spongiotrophoblast cell morphology	J:65498
	abnormal spongiotrophoblast layer morphology	J:65498
	abnormal trophoblast giant cell morphology	J:65498
	abnormal trophoblast layer morphology	J:65498
	decreased spongiotrophoblast cell number	J:65498
	embryonic growth retardation	J:65498
	embryonic lethality during organogenesis, complete penetrance	J:65498
	impaired placental function	J:65498
	increased trophoblast giant cell number	J:65498
	small placenta	J:65498
Sox9tm1Gsr/Sox9tm1Gsr Krt19tm1(cre)Mmt/Krt19+ involves: 129P2/OlaHsd * C57BL/6	abnormal cartilage development	J:104330
	abnormal testis development	J:104330
	absent Leydig cells	J:104330
	absent testis cords	J:104330
	embryonic lethality during organogenesis, incomplete penetrance	J:104330
	failure of Mullerian duct regression	J:104330
	heart hypoplasia	J:104330
	impaired cranial neural crest cell differentiation	J:104330
	primary sex reversal	J:104330