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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptpn6
protein tyrosine phosphatase, non-receptor type 6
MGI:96055
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Btkxid/?
Ptpn6me/Ptpn6me
involves: C57BL/6J * CBA/N * NFS 		abnormal skin condition J:30994
absent limbs J:30994
decreased body weight J:30994
increased autoantibody level J:30994
increased IgM level J:30994
increased splenocyte proliferation J:30994
premature death J:30994
Cd22tm1Eac/Cd22+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
Cd22tm1Eac/Cd22+
Lyntm1Ard/Lyn+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
increased IgM level J:110531
Ighmtm1Cgn/Ighmtm1Cgn
Ptpn6me-v/Ptpn6me-v
involves: 129S7/SvEvBrd * C57BL/6J 		decreased retina photoreceptor cell number J:108375
retina photoreceptor degeneration J:108375
Iglc1tm2Ust/Iglc1tm2Ust
Ptpn6me-v/Ptpn6me-v
involves: 129S7/SvEvBrd * C57BL/6J 		decreased B cell number J:113218
Irak4m1Btlr/Irak4m1Btlr
Ptpn6m1Btlr/Ptpn6m1Btlr
C57BL/6J-Ptpn6m1Btlr Irak4m1Btlr 		normal immune system phenotype J:142845
Lyntm1Ard/Lyn+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal mature B cell morphology J:110531
Myd88poc/Myd88poc
Ptpn6m1Btlr/Ptpn6m1Btlr
C57BL/6J-Ptpn6m1Btlr Myd88poc 		normal immune system phenotype J:142845
Ptpn6m1Btlr/Ptpn6m1Btlr
Stat1m1Btlr/Stat1m1Btlr
C57BL/6J-Stat1m1Btlr Ptpn6m1Btlr 		ulcerated autopod J:142845
Ptpn6m1Btlr/Ptpn6m1Btlr
Ticam1Lps2/Ticam1Lps2
C57BL/6J-Ptpn6m1Btlr Ticam1Lps2 		ulcerated autopod J:142845
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal mature B cell morphology J:110531
Ptpn6me-v/Ptpn6me-v
involves: 129S7/SvEvBrd * C57BL/6J 		decreased retina photoreceptor cell number J:108375
retina photoreceptor degeneration J:108375
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory