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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bmi1
Bmi1 polycomb ring finger oncogene
MGI:88174
66 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Bmi1tm1(cre/ERT)Mrc/\Bmi1+
\Ctnnb1tm1Mmt/\Ctnnb1+
involves: 129S1/Sv * 129X1/SvJ 		abnormal crypts of Lieberkuhn morphology J:138364
increased intestinal adenoma incidence J:138364
premature death J:138364
\Bmi1tm1(cre/ERT)Mrc/\Bmi1+
\Gt(ROSA)26Sortm1(DTA)Mrc/\Gt(ROSA)26Sor+
involves: 129S1/Sv * 129X1/SvJ 		abnormal duodenum crypts of Lieberkuhn morphology J:138364
abnormal jejunum crypts of Lieberkuhn morphology J:138364
premature death J:138364
slow postnatal weight gain J:138364
\Bmi1tm1.1Lees/\Bmi1tm1.1Lees
\Apctm2Cip/\Apc+
\Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 		normal cellular phenotype J:204354
decreased alimentary system tumor incidence J:204354
decreased colon tumor incidence J:204354
decreased intestinal adenoma incidence J:204354
\Bmi1tm1Brn/\Bmi1+
\E2f6tm1Lees/\E2f6+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
\Bmi1tm1Brn/\Bmi1+
\E2f6tm1Lees/\E2f6tm1Lees
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
\Bmi1tm1Brn/\Bmi1tm1Brn
\Apctm2Cip/\Apc+
\Cdkn2atm1Cjs/\Cdkn2atm1Cjs
\Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		cachexia J:204354
hunched posture J:204354
increased intestinal adenoma incidence J:204354
\Bmi1tm1Brn/\Bmi1tm1Brn
\Apctm2Cip/\Apc+
\Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased alimentary system tumor incidence J:204354
decreased colon tumor incidence J:204354
decreased intestinal adenoma incidence J:204354
increased apoptosis J:204354
\Bmi1tm1Brn/\Bmi1tm1Brn
\E2f6tm1Lees/\E2f6+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal vertebrae morphology J:134271
cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
\Bmi1tm1Brn/\Bmi1tm1Brn
\E2f6tm1Lees/\E2f6tm1Lees
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal bone marrow cell morphology/development J:134271
abnormal cell cycle J:134271
abnormal vertebrae morphology J:134271
anemia J:134271
ataxia J:134271
cerebellum hypoplasia J:134271
cervical vertebral transformation J:134271
decreased bone marrow cell number J:134271
decreased cell proliferation J:134271
decreased double-positive T cell number J:134271
decreased hematopoietic cell number J:134271
early cellular replicative senescence J:134271
lumbar vertebral transformation J:134271
postnatal growth retardation J:134271
postnatal lethality, incomplete penetrance J:134271
premature death J:134271
prenatal lethality, incomplete penetrance J:134271
thoracic vertebral transformation J:134271
\Bmi1tm1Brn/\Bmi1tm1Brn
\Rnf2tm1Mvl/\Rnf2+
involves: 129/Ola * FVB 		abnormal axial skeleton morphology J:82399
abnormal cerebellar granule layer morphology J:82399
abnormal cerebellar molecular layer J:82399
abnormal gait J:82399
abnormal Purkinje cell dendrite morphology J:82399
decreased body size J:82399
decreased body weight J:82399
gliosis J:82399
impaired coordination J:82399
postnatal growth retardation J:82399
premature death J:82399
small cerebellum J:82399
\Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/\Gt(ROSA)26Sor+
\Bmi1tm1(cre/ERT)Mrc/\Bmi1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		increased tumor incidence J:194308
\Pcgf2tm1Hko/\Pcgf2+
\Bmi1tm1Brn/\Bmi1tm1Brn
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal axial skeleton morphology J:68216
abnormal cervical atlas morphology J:68216
abnormal craniofacial bone morphology J:68216
abnormal rib joint morphology J:68216
abnormal scapula morphology J:68216
abnormal sternum ossification J:68216
acromion hypoplasia J:68216
cervical vertebral transformation J:68216
cleft secondary palate J:68216
scapular bone foramen J:68216
split exoccipital bone J:68216
\Pcgf2tm1Hko/\Pcgf2tm1Hko
\Bmi1tm1Brn/\Bmi1+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal axial skeleton morphology J:68216
abnormal cervical atlas morphology J:68216
abnormal craniofacial bone morphology J:68216
abnormal rib joint morphology J:68216
abnormal scapula morphology J:68216
abnormal sternum ossification J:68216
acromion hypoplasia J:68216
cervical vertebral transformation J:68216
cleft secondary palate J:68216
scapular bone foramen J:68216
split exoccipital bone J:68216
\Pcgf2tm1Hko/\Pcgf2tm1Hko
\Bmi1tm1Brn/\Bmi1tm1Brn
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal brain morphology J:68216
abnormal cervical atlas morphology J:68216
abnormal dorsal aorta morphology J:68216
abnormal first pharyngeal arch morphology J:68216
abnormal neural tube morphology J:68216
abnormal notochord morphology J:68216
abnormal optic eminence morphology J:68216
abnormal second pharyngeal arch morphology J:68216
abnormal somatic mesoderm morphology J:68216
abnormal somite development J:68216
abnormal tail bud morphology J:68216
cervical vertebral transformation J:68216
embryonic growth arrest J:68216
embryonic lethality during organogenesis, complete penetrance J:68216
hindbrain hypoplasia J:68216
increased neural tube apoptosis J:68216
small notochord J:68216
split notochord J:68216
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory