61 phenotypes from 9 alleles in 17 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grhl3ct-2J/Grhl3ct-2J C57BL/6J-Grhl3ct-2J/J	abnormal neural tube morphology	J:87349
	curly tail	J:87349
Grhl3ct-J/Grhl3ct-J STOCK T(7;15)9H	curly tail	J:87487
	open neural tube	J:87487
Grhl3ct/Grhl3+ involves: C57BL/6 * GFF	curly tail	J:24376
Grhl3ct/Grhl3ct-J Not Specified	curly tail	J:87487
	open neural tube	J:87487
Grhl3ct/Grhl3ct GFF-Grhl3ct	abnormal neural tube closure	J:1549, J:6246
	curly tail	J:6864
	exencephaly	J:6245, J:6864
	fetal growth retardation	J:6864
	spina bifida	J:6864
Grhl3ct/Grhl3ct involves: CBA/Gr * GFF	abnormal dorsal-ventral axis patterning	J:79
	anencephaly	J:264
	curly tail	J:264
	delayed neural tube closure	J:79
	spina bifida	J:264
Grhl3ct/Grhl3ct involves: GFF	abnormal neural tube closure	J:14716
	curly tail	J:14716
	spina bifida	J:14716
Grhl3ct/Grhl3ct STOCK Grhl3ct/J	curly tail	J:86772
	exencephaly	J:86772
	spina bifida cystica	J:86772
Grhl3ct/Grhl3ct Tg(Grhl3)1Ndeg/0 involves: GFF	normal nervous system phenotype	J:129979
Grhl3ct/Grhl3tm1Jane involves: 129S1/Sv * C57BL/6 * STOCK ct/J	spina bifida	J:86772
Grhl3tm1(cre)Cgh/Grhl3tm1(cre)Cgh involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal brain development	J:157446
	abnormal neural tube morphology	J:157446
	exencephaly	J:157446
	spina bifida	J:157446
Grhl3tm1a(EUCOMM)Wtsi/Grhl3+ C57BL/6N-Grhl3tm1a(EUCOMM)Wtsi/Ics	abnormal eye morphology	J:165965
	abnormal locomotor activation	J:165965
	abnormal retina morphology	J:165965
	decreased blood urea nitrogen level	J:165965
	decreased circulating alkaline phosphatase level	J:165965
	decreased circulating triglyceride level	J:165965
	decreased IgE level	J:165965
	increased circulating calcium level	J:165965
	increased circulating glucose level	J:165965
Grhl3tm1Bogi/Grhl3+ involves: C57BL/6J	abnormal craniofacial development	J:226218
	abnormal periderm development	J:226218
Grhl3tm1Bogi/Grhl3tm1Bogi involves: C57BL/6 * C57BL/6J	abnormal palate development	J:226218
	abnormal periderm development	J:226218
	cleft palate	J:226218
Grhl3tm1Bogi/Grhl3tm1Bogi involves: C57BL/6J	abnormal corneocyte morphology	J:114626
	abnormal epidermal layer morphology	J:114626
	abnormal epidermis stratum basale morphology	J:114626
	abnormal epidermis stratum corneum morphology	J:114626
	abnormal epidermis stratum granulosum morphology	J:114626
	abnormal intestine morphology	J:114626
	abnormal keratinocyte differentiation	J:114626
	abnormal lipid level	J:114626
	abnormal neural tube closure	J:114626
	abnormal stomach epithelium morphology	J:114626
	curly tail	J:114626
	epidermal hyperplasia	J:114626
	exencephaly	J:114626
	eyelids open at birth	J:114626
	impaired skin barrier function	J:114626
	increased keratinocyte proliferation	J:114626
	intestinal hemorrhage	J:114626
	perinatal lethality, complete penetrance	J:114626
	spina bifida	J:114626
	thick epidermis	J:114626
	thick epidermis stratum spinosum	J:114626
Grhl3tm1Jane/Grhl3+ involves: 129S1/Sv	normal neoplasm	J:178952
Grhl3tm1Jane/Grhl3tm1Jane involves: 129S1/Sv	abnormal vertebral pedicle morphology	J:164805
	increased keratinocyte proliferation	J:178952
	spina bifida	J:164805
	thick epidermis	J:178952
Grhl3tm1Jane/Grhl3tm1Jane involves: 129S1/Sv * C57BL/6	abnormal corneocyte envelope morphology	J:233531
	abnormal vertebrae morphology	J:86772
	abnormal vertebral spinous process morphology	J:86772
	absent vertebral arch	J:86772
	decreased embryo size	J:86772
	exencephaly	J:86772
	kinked tail	J:86772
	kyphosis	J:86772
	preweaning lethality, complete penetrance	J:86772
	spina bifida	J:86772
Grhl3tm1Jane/Grhl3tm3.1Jane Tg(KRT14-cre)8Brn/0 involves: 129S1/Sv * C57BL/6 * FVB/N	epidermal hyperplasia	J:178952
	increased incidence of tumors by chemical induction	J:178952
	increased skin papilloma incidence	J:178952
	increased skin squamous cell carcinoma incidence	J:178952
	normal integument phenotype	J:178952, J:233531
Grhl3tm1Jane/Grhl3tm3.1Jane Tg(MMTV-cre)4Mam/0 involves: 129S1/Sv * C57BL/6 * FVB	abnormal skin morphology	J:178952
	abnormal skin physiology	J:178952
	increased tumor incidence	J:178952
Grhl3tm3.1Jane/Grhl3tm3.1Jane involves: 129S1/Sv * C57BL/6	no abnormal phenotype detected	J:178952