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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lbr
lamin B receptor
MGI:2138281
112 phenotypes from 7 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lbrem1(IMPC)Tcp/Lbrem1(IMPC)Tcp
C57BL/6N-Lbrem1(IMPC)Tcp/Tcp
abnormal bone structure J:211773
abnormal coat/ hair morphology J:211773
abnormal cranium morphology J:211773
abnormal digit morphology J:211773
abnormal forelimb morphology J:211773
abnormal skin morphology J:211773
abnormal tail morphology J:211773
absent vibrissae J:211773
decreased body length J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating alkaline phosphatase level J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
decreased mean corpuscular hemoglobin J:211773
decreased prepulse inhibition J:211773
enlarged lymph nodes J:211773
impaired pupillary reflex J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
preweaning lethality, incomplete penetrance J:211773
short tibia J:211773
shortened PR interval J:211773
small seminal vesicle J:211773
small testis J:211773
LbrGt(XE569)Byg/LbrGt(XE569)Byg
involves: 129P2/OlaHsd * C57BL/6Cr
abnormal cell nucleus morphology J:138854
abnormal eye physiology J:138854
abnormal granulocyte differentiation J:138854
abnormal granulocyte morphology J:138854
abnormal lymphocyte morphology J:138854
abnormal neutrophil morphology J:138854
abnormal nuclear lamina morphology J:138854
abnormal rib morphology J:138854
decreased subcutaneous adipose tissue amount J:138854
enlarged lateral ventricles J:138854
enlarged lymph nodes J:138854
female infertility J:138854
gliosis J:138854
normal homeostasis/metabolism phenotype J:138854
hyperkeratosis J:138854
increased neuron apoptosis J:138854
male infertility J:138854
postnatal lethality, incomplete penetrance J:138854
premature death J:138854
prenatal lethality, incomplete penetrance J:138854
scoliosis J:138854
uterus hypoplasia J:138854
Lbric-2J/Lbric-2J
involves: A/J
abnormal blood cell morphology/development J:80915
abnormal coat/ hair morphology J:80915
abnormal epidermal layer morphology J:80915
abnormal immune system cell morphology J:80915
abnormal nervous system morphology J:80915
decreased body size J:80915
perinatal lethality J:80915
prenatal lethality J:80915
Lbric-3J/Lbric-3J
involves: A/J
abnormal blood cell morphology/development J:80915
abnormal coat/ hair morphology J:80915
abnormal epidermal layer morphology J:80915
abnormal immune system cell morphology J:80915
abnormal nervous system morphology J:80915
decreased body size J:80915
perinatal lethality J:80915
prenatal lethality J:80915
Lbric-J/Lbr+
(NZW/LacJ x C57BL/6J-Lbric-J/J)F1
abnormal kidney morphology J:234168
abnormal neutrophil morphology J:234168
abnormal renal glomerulus morphology J:234168
enlarged spleen J:234168
glomerulosclerosis J:234168
increased anti-chromatin antibody level J:234168
increased anti-nuclear antigen antibody level J:234168
increased autoantibody level J:234168
increased susceptibility to systemic lupus erythematosus J:234168
renal interstitial fibrosis J:234168
Lbric-J/Lbr+
C57BL/6J-Lbric-J
abnormal granulocyte morphology J:80915
Lbric-J/Lbric-J
C57BL/6J-Lbric-J
abnormal cell nucleus morphology J:80915
abnormal eosinophil morphology J:80915
abnormal lymphocyte morphology J:80915
abnormal neutrophil morphology J:80915
decreased body size J:80915
dilated lateral ventricle J:80915
dilated piliary canal J:80915
epidermal hyperplasia J:80915
hydrocephaly J:80915
orthokeratosis J:80915
perinatal lethality, incomplete penetrance J:80915
prenatal lethality, incomplete penetrance J:80915
scaly skin J:80915
sparse hair J:80915
syndactyly J:80915
Lbric-J/Lbric-J
involves: 129S4/SvJae * C57BL/6
abnormal long bone epiphyseal plate morphology J:143838
abnormal neutrophil differentiation J:143838
abnormal spleen morphology J:143838
abnormal trabecular bone morphology J:143838
dry skin J:143838
postnatal growth retardation J:143838
scaly skin J:143838
sparse hair J:143838
syndactyly J:143838
Lbric-J/Lbrlym3
C57BL/6-Lbric-J/Lbrlym3
decreased leukocyte cell number J:180355
decreased lymphocyte cell number J:180355
normal mortality/aging J:180355
Lbric/Lbr+
Not Specified
abnormal cell nucleus morphology J:5569
Lbric/Lbric
Not Specified
abnormal cell nucleus morphology J:5569
abnormal epidermal layer morphology J:5552
abnormal epidermis stratum corneum morphology J:13065
abnormal epidermis stratum granulosum morphology J:5740
abnormal hair growth J:13065
abnormal respiration J:13065
abnormal skin condition J:13065
abnormal vibrissa morphology J:13065
absent scrotum J:13065
constricted vagina orifice J:13065
cryptorchism J:13065
decreased vocalization J:13065
delayed hair appearance J:13065
epidermis stratum spinosum hyperplasia J:13065
increased keratohyalin granule size J:5740
increased mitochondrial fission J:5740
male infertility J:13065
postnatal growth retardation J:13065
postnatal lethality J:13065
reduced female fertility J:13065
scaly skin J:13065
short vibrissae J:13065
tail necrosis J:13065
Lbrlym3/Lbr+
C57BL/6-Lbrlym3
abnormal neutrophil morphology J:180355
Lbrlym3/Lbrlym3
C57BL/6-Lbrlym3
abnormal B cell physiology J:180355
abnormal blood cell morphology/development J:180355
abnormal lymphocyte cell number J:180355
abnormal lymphocyte morphology J:180355
abnormal neutrophil morphology J:180355
abnormal T cell physiology J:180355
decreased B cell number J:180355
decreased CD4-positive, alpha-beta T cell number J:180355
decreased CD8-positive, alpha-beta T cell number J:180355
decreased leukocyte cell number J:180355
decreased lymphocyte cell number J:180355
decreased T cell number J:180355
decreased T cell proliferation J:180355
lymph node hypoplasia J:180355
normal skeleton phenotype J:180355
spleen hypoplasia J:180355
thymus hypoplasia J:180355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory