Rnf10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf10
ring finger protein 10
MGI:1859162

71 phenotypes from 5 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rnf10^em1(IMPC)Bay/Rnf10^em1(IMPC)Bay C57BL/6N-Rnf10^em1(IMPC)Bay/Bay	abnormal retina blood vessel morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased total retina thickness	J:211773
	increased vertical activity	J:211773
Rnf10^em1(IMPC)J/Rnf10^em1(IMPC)J C57BL/6NJ-Rnf10^em1(IMPC)J/J	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	decreased exploration in new environment	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased bone mineral content	J:211773
	increased vertical activity	J:211773
	limb grasping	J:211773
Rnf10^em1(IMPC)Mbp/Rnf10^em1(IMPC)Mbp C57BL/6N-Rnf10^em1(IMPC)Mbp/Ucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	anophthalmia	J:211773
	decreased brain weight	J:211773
	decreased startle reflex	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating glucose level	J:211773
Rnf10^{tm1a(KOMP)Wtsi}/Rnf10^{tm1a(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1a(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating cholesterol level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	increased body weight	J:175295
	increased circulating cholesterol level	J:175295
	increased circulating HDL cholesterol level	J:175295
	increased circulating triglyceride level	J:175295
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ieg	abnormal lens morphology	J:211773
	increased grip strength	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/MbpMmucd	increased circulating HDL cholesterol level	J:211773
	microcephaly	J:211773
	syndactyly	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ucd	decreased circulating serum albumin level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased total body fat amount	J:211773
	enlarged heart	J:211773
	increased heart weight	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Bay	abnormal behavior	J:211773
	abnormal spleen morphology	J:211773
	decreased prepulse inhibition	J:211773
	hyperactivity	J:211773
	increased vertical activity	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/H	abnormal gait	J:211773
	decreased anxiety-related response	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating total protein level	J:211773
	decreased hemoglobin content	J:211773
	decreased prepulse inhibition	J:211773
	decreased spleen weight	J:211773
	hyperactivity	J:211773
	increased large unstained cell number	J:211773
	increased red blood cell distribution width	J:211773
	limb grasping	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ics	abnormal behavior	J:211773
	abnormal freezing behavior	J:211773
	decreased body length	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased exploration in new environment	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	decreased lymphocyte cell number	J:211773
	decreased prepulse inhibition	J:211773
	decreased total retina thickness	J:211773
	improved glucose tolerance	J:211773
	increased anxiety-related response	J:211773
	increased monocyte cell number	J:211773
	increased vertical activity	J:211773
	shortened QT interval	J:211773
	shortened ST segment	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ieg	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased locomotor activity	J:211773
	decreased vertical activity	J:211773
	hyperactivity	J:211773
	increased circulating triglyceride level	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/J	abnormal auditory brainstem response	J:211773
	convulsive seizures	J:211773
	decreased circulating glucose level	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased prepulse inhibition	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	increased circulating sodium level	J:211773
	increased heart rate variability	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/MbpMmucd	microcephaly	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	syndactyly	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Rbrc	decreased bone mineral density	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased bone mineral content	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ucd	preweaning lethality, incomplete penetrance	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Wtsi	abnormal auditory brainstem response	J:211773
	abnormal tibia morphology	J:211773
	absent pinna reflex	J:211773
	decreased body length	J:211773
	decreased grip strength	J:211773
	increased bone mineral content	J:211773
	increased circulating creatinine level	J:211773
	increased lean body mass	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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