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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
MGI:1344376
37 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Cd19tm1(cre)Cgn/\Cd19+
\Tnfsf13btm1Msc/\Tnfsf13btm1Msc
\Traf2tm1Rbr/\Traf2tm1Rbr
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		increased follicular B cell number J:132877
increased marginal zone B cell number J:132877
\Cd40tm1Kik/\Cd40tm1Kik
\Tg(Tnfsf13b)1Fma/?
B6.Cg-Cd40tm1Kik Tg(Tnfsf13b)1Fma 		abnormal B cell activation J:113556
abnormal class switch recombination J:113556
absent spleen germinal center J:113556
glomerulonephritis J:113556
increased anti-double stranded DNA antibody level J:113556
increased marginal zone B cell number J:113556
increased urine protein level J:113556
renal glomerular immunoglobulin deposits J:113556
\Chuktm2Mka/\Chuktm2Mka
\Tg(Tnfsf13b)1Fma/?
B6.Cg-Chuktm2Mka Tg(Tnfsf13b)1Fma 		abnormal B cell activation J:113556
absent spleen marginal zone J:113556
decreased marginal zone B cell number J:113556
increased anti-double stranded DNA antibody level J:113556
increased transitional stage B cell number J:113556
increased urine protein level J:113556
\Ighatm1(Myc)Janz/\Igha+
\Tg(Tnfsf13b)1Fma/0
involves: 129S1/Sv * C57BL/6 * DBA/2J 		enlarged spleen J:166158
increased B cell number J:166158
increased chronic lymphocytic leukemia incidence J:166158
increased lymphocyte cell number J:166158
increased mature B cell number J:166158
increased spleen white pulp amount J:166158
premature death J:166158
\Ighatm1Grh/\Ighatm1Grh
\Tg(Tnfsf13b)1Fma/\Tg(Tnfsf13b)1Fma
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 		normal immune system phenotype J:178227
\Nba10NZB/\Nba10NZB
\Tg(Tnfsf13b)1Fma/0
involves: C57BL/6 * DBA/2J * NZB 		glomerulonephritis J:134128
increased anti-chromatin antibody level J:134128
increased anti-double stranded DNA antibody level J:134128
increased B cell number J:134128
increased IgG level J:134128
increased IgM level J:134128
increased marginal zone B cell number J:134128
increased susceptibility to systemic lupus erythematosus J:134128
\Nfkb1tm1Bal/\Nfkb1tm1Bal
\Tg(Tnfsf13b)1Fma/?
B6.Cg-Nfkb1tm1Bal Tg(Tnfsf13b)1Fma 		abnormal B cell activation J:113556
abnormal class switch recombination J:113556
decreased marginal zone B cell number J:113556
normal immune system phenotype J:113556
increased transitional stage B cell number J:113556
\Nfkb2tm2Brv/\Nfkb2tm2Brv
\Tg(Tnfsf13b)1Fma/?
B6.Cg-Nfkb2tm2Brv Tg(Tnfsf13b)1Fma 		abnormal B cell activation J:113556
absent spleen marginal zone J:113556
decreased marginal zone B cell number J:113556
normal immune system phenotype J:113556
increased urine protein level J:113556
\Sle1NZW/\Sle1NZW
\Tg(Tnfsf13b)1Fma/0
involves: C57BL/6 * DBA/2J * NZW 		glomerulonephritis J:134128
increased B cell number J:134128
increased IgG level J:134128
increased IgM level J:134128
increased marginal zone B cell number J:134128
increased susceptibility to systemic lupus erythematosus J:134128
\Tg(Tnfsf13b)1Fma/?
\Tnfrsf13btm1Rjb/\Tnfrsf13btm1Rjb
B6.Cg-Tnfrsf13btm1Rjb Tg(Tnfsf13b)1Fma 		abnormal class switch recombination J:113556
\Tg(Tnfsf13b)1Fma/?
\Tnfrsf13ctm1Mass/\Tnfrsf13ctm1Mass
B6.Cg-Tnfrsf13ctm1Mass Tg(Tnfsf13b)1Fma 		abnormal class switch recombination J:113556
\Tg(Tnfsf13b)1Fma/0
\Tnfsf14tm1Kpf/\Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J 		abnormal mesangial cell morphology J:114782
abnormal spleen germinal center morphology J:114782
abnormal spleen marginal zone morphology J:114782
increased B cell number J:114782
increased IgA level J:114782
increased plasma cell number J:114782
renal glomerular immunoglobulin deposits J:114782
\Tnfsf13btm1Msc/\Tnfsf13btm1Msc
\Traf2tm1Rbr/\Traf2tm1Rbr
involves: 129S2/SvPas * C57BL/6 		absent follicular B cells J:132877
absent marginal zone B cells J:132877
decreased mature B cell number J:132877
\Traf3ip2tm1.1Lix/\Traf3ip2tm1.1Lix
\Tnfsf13btm1Msc/\Tnfsf13btm1Msc
involves: 129 * 129S2/SvPas * BALB/c 		decreased B cell number J:138560
decreased follicular B cell number J:138560
decreased mature B cell number J:138560
decreased transitional stage B cell number J:138560
enlarged lymph nodes J:93923
enlarged spleen J:93923
increased autoantibody level J:138560
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory