53 phenotypes from 7 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alpltm1(cre)Nagy/Alpl+ Pknox1tm1.1Rygo/Pknox1tm1.1Rygo involves: 129 * C57BL/6 * C57BL/6JJcl	abnormal spermatogonia morphology	J:258387
	abnormal spermatogonia proliferation	J:258387
	arrest of spermatogenesis	J:258387
	azoospermia	J:258387
	decreased male germ cell number	J:258387
	decreased testis weight	J:258387
	increased male germ cell apoptosis	J:258387
	seminiferous tubule degeneration	J:258387
	small testis	J:258387
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+ Pknox1tm1.1Rygo/Pknox1tm1.1Rygo involves: 129 * C57BL/6 * C57BL/6JJcl	abnormal spermatogonia morphology	J:258387
	arrest of spermatogenesis	J:258387
	azoospermia	J:258387
	decreased male germ cell number	J:258387
	increased testis apoptosis	J:258387
	normal reproductive system phenotype	J:258387
	seminiferous tubule degeneration	J:258387
Pknox1Gt(OST71835)Lex/Pknox1Gt(OST71835)Lex B6.129S5-Pknox1Gt(OST71835)Lex	abnormal erythropoiesis	J:111418
	abnormal eye development	J:111418
	abnormal eye morphology	J:111418
	abnormal liver development	J:111418
	abnormal prenatal growth/weight/body size	J:111418
	abnormal retina neuronal layer morphology	J:111418
	abnormal retina pigment epithelium morphology	J:111418
	anemia	J:111418
	decreased angiogenesis	J:111418
	decreased erythroid progenitor cell number	J:111418
	decreased fetal size	J:111418
	decreased hematocrit	J:111418
	edema	J:111418
	hemorrhage	J:111418
	increased nucleated erythrocyte cell number	J:111418
	pallor	J:111418
	perinatal lethality, complete penetrance	J:111418
	small lens	J:111418
Pknox1Gt(OST71835)Lex/Pknox1Gt(OST71835)Lex involves: 129S5/SvEvBrd	abnormal blood cell morphology/development	J:192251
Pknox1Gt(OST71835)Lex/Pknox1Gt(OST71835)Lex involves: 129S5/SvEvBrd * C57BL/6	decreased birth body size	J:103769
	decreased single-positive T cell number	J:103769
	increased double-negative T cell number	J:103769
	increased T cell apoptosis	J:103769
	lethality throughout fetal growth and development, complete penetrance	J:103769
	thymus hypoplasia	J:103769
Pknox1Gt(OST71835)Lex/Pknox1Gt(OST71835)Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased body weight	J:103485
	decreased percent body fat/body weight	J:103485
Pknox1tm1.1Xzh/Pknox1tm1.1Xzh Tfap2atm1(cre)Moon/Tfap2a+ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	normal vision/eye phenotype	J:182769
Pknox1tm1.1Xzh/Pknox1tm1.1Xzh Tg(Pax6-cre,GFP)1Pgr/0 involves: 129S6/SvEvTac * C57BL/6 * FVB	no abnormal phenotype detected	J:182769
Pknox1tm1.2Xzh/Pknox1tm1.2Xzh involves: C57BL/6	embryonic lethality, complete penetrance	J:182769
Pknox1tm1Fbla/Pknox1tm1Fbla B6.Cg-Pknox1tm1Fbla	abnormal embryonic tissue morphology	J:165811
	abnormal extraembryonic tissue morphology	J:165811
	abnormal pluripotent precursor cell morphology	J:165811
	abnormal visceral endoderm morphology	J:165811
	absent anterior visceral endoderm	J:165811
	absent mesoderm	J:165811
	decreased embryo size	J:165811
	embryonic growth retardation	J:165811
	embryonic lethality between implantation and somite formation, complete penetrance	J:165811
	failure of primitive streak formation	J:165811
Pknox1tm1Ngc/Pknox1tm1Ngc Not Specified	embryonic lethality between implantation and somite formation, complete penetrance	J:111418
Pknox1tm2.1Fbla/Pknox1tm2.1Fbla Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ involves: 129P2/OlaHsd	decreased pre-B cell number	J:192251
	increased pro-B cell number	J:192251