139 phenotypes from 6 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfe2l2em1(IMPC)Ccpcz/Nfe2l2em1(IMPC)Ccpcz C57BL/6NCrl-Nfe2l2em1(IMPC)Ccpcz/Ccpcz	abnormal lymph node morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal tooth morphology	J:211773
	decreased body weight	J:211773
	decreased circulating glucose level	J:211773
	enlarged lymph nodes	J:211773
	enlarged seminal vesicle	J:211773
	enlarged thymus	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating phosphate level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean platelet volume	J:211773
Nfe2l2tm1.1Sred/Nfe2l2tm1.1Sred Tg(Scgb1a1-cre)1Grau/0 involves: C57BL/6 * C57BL/6J	abnormal cell death	J:191916
	decreased interleukin-1 beta secretion	J:191916
	decreased tumor necrosis factor secretion	J:191916
	increased susceptibility to injury	J:191916
Nfe2l2tm1Mym/Nfe2l2+ involves: 129P2/OlaHsd	abnormal enamel morphology	J:95372
	abnormal iron level	J:95372
Nfe2l2tm1Mym/Nfe2l2tm1Mym B6.129P2-Nfe2l2tm1Mym	decreased body weight	J:208590
	normal homeostasis/metabolism phenotype	J:208590
Nfe2l2tm1Mym/Nfe2l2tm1Mym involves: 129P2/OlaHsd	abnormal enamel morphology	J:95372
	abnormal incisor color	J:95372
	abnormal iron homeostasis	J:95372
	abnormal iron level	J:95372
	abnormal tooth morphology	J:95372
	ameloblast degeneration	J:95372
	increased liver iron level	J:95372
Nfe2l2tm1Mym/Nfe2l2tm1Mym involves: 129P2/OlaHsd * C57BL/6	abnormal leukocyte adhesion	J:150597
	abnormal physiological response to xenobiotic	J:136120
	cachexia	J:136120
	hypoglycemia	J:136120
	increased circulating alanine transaminase level	J:136120
	increased circulating interleukin-6 level	J:136120
	increased circulating tumor necrosis factor level	J:136120
	increased hepatocyte apoptosis	J:136120
	increased susceptibility to experimental autoimmune uveoretinitis	J:150597
	increased susceptibility to xenobiotic induced morbidity/mortality	J:136120
	liver inflammation	J:136120
	macrovesicular hepatic steatosis	J:136120
	oxidative stress	J:150597
Nfe2l2tm1Mym/Nfe2l2tm1Mym involves: 129P2/OlaHsd * C57BL/6J	increased susceptibility to induced colitis	J:116676
Nfe2l2tm1Mym/Nfe2l2tm1Mym involves: 129P2/OlaHsd * CD-1	abnormal behavior	J:122813
	circling	J:122813
	increased acute inflammation	J:122813
	increased cerebral infarct size	J:122813
	increased susceptibility to ischemic brain injury	J:122813
Nfe2l2tm1Mym/Nfe2l2tm1Mym involves: 129P2/OlaHsd * ICR	abnormal glomerular capillary morphology	J:104016
	abnormal glomerular mesangium morphology	J:104016
	abnormal macrophage physiology	J:118068
	abnormal physiological response to xenobiotic	J:68072, J:118068
	abnormal renal glomerulus morphology	J:104016
	abnormal respiratory system physiology	J:118068
	decreased CD4-positive, alpha-beta T cell number	J:104016
	decreased T cell number	J:104016
	decreased urine creatinine level	J:104016
	enlarged lymph nodes	J:104016
	glomerular crescent	J:104016
	glomerulonephritis	J:104016
	glomerulosclerosis	J:104016
	normal hematopoietic system phenotype	J:41943
	increased anti-double stranded DNA antibody level	J:104016
	increased anti-nuclear antigen antibody level	J:104016
	increased IgG level	J:104016
	increased IgM level	J:104016
	increased incidence of tumors by chemical induction	J:68072
	increased kidney cell proliferation	J:104016
	increased lung weight	J:118068
	increased mesangial cell number	J:104016
	increased spleen weight	J:104016
	increased stomach tumor incidence	J:68072
	increased urine protein level	J:104016
	lung inflammation	J:118068
	oxidative stress	J:104016
	premature death	J:104016
	pulmonary fibrosis	J:118068
	weight loss	J:118068
Nfe2l2tm1Ney/Nfe2l2tm1Ney involves: 129X1/SvJ * C57BL/6	normal hematopoietic system phenotype	J:47440
Nfe2l2tm1Sud/Nfe2l2tm1Sud involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:101977
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk B6.129X1-Nfe2l2tm1Ywk	abnormal enzyme/coenzyme activity	J:165602
	abnormal enzyme/coenzyme level	J:165602, J:310044
	abnormal lipid homeostasis	J:165602
	abnormal male germ cell morphology	J:165602
	abnormal ovary physiology	J:310044
	abnormal seminiferous tubule morphology	J:165602
	abnormal spermatogenesis	J:165602
	asthenozoospermia	J:165602
	normal behavior/neurological phenotype	J:165602
	normal cellular phenotype	J:310044
	decreased epididymis weight	J:165602
	decreased glutathione level	J:165602, J:310044
	decreased glutathione peroxidase activity	J:165602
	decreased primordial ovarian follicle number	J:310044
	decreased tertiary ovarian follicle number	J:310044
	decreased testis weight	J:165602
	early reproductive senescence	J:310044
	normal homeostasis/metabolism phenotype	J:165602, J:310044
	increased anti-double stranded DNA antibody level	J:165602
	increased male germ cell apoptosis	J:165602
	normal limbs/digits/tail phenotype	J:165602
	normal mortality/aging	J:165602
	oligozoospermia	J:165602
	oxidative stress	J:165602
	polyovular ovarian follicle	J:310044
	reduced male fertility	J:165602
	normal renal/urinary system phenotype	J:165602
	seminiferous tubule degeneration	J:165602
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk B6.129X1-Nfe2l2tm1Ywk/J	abnormal neutrophil physiology	J:233699
	abnormal periodontal ligament morphology	J:233699
	alveolar process atrophy	J:233699
	decreased catalase level	J:233699
	oxidative stress	J:233699
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk involves: 129X1/SvJ	abnormal erythrocyte physiology	J:91407
	abnormal liver physiology	J:130473
	abnormal myelin sheath morphology	J:122195
	abnormal spleen physiology	J:91407
	abnormal splenocyte physiology	J:91407
	abnormal tooth color	J:91407
	acanthocytosis	J:91407
	anisocytosis	J:91407
	astrocytosis	J:122195
	decreased circulating interleukin-1 beta level	J:100106
	decreased erythrocyte cell number	J:91407
	decreased hematocrit	J:91407
	decreased hemoglobin content	J:91407
	decreased hepatocyte proliferation	J:130473
	decreased liver weight	J:130473
	delayed liver regeneration	J:130473
	normal embryo phenotype	J:37053
	enlarged spleen	J:91407
	normal hematopoietic system phenotype	J:37053
	hemolytic anemia	J:91407
	normal homeostasis/metabolism phenotype	J:100106
	increased cellular sensitivity to hydrogen peroxide	J:91407
	increased circulating bilirubin level	J:130473
	increased circulating interleukin-1 beta level	J:100106
	increased fibroblast apoptosis	J:86725
	increased lactate dehydrogenase level	J:91407
	increased macrophage cell number	J:100106
	increased number of Howell-Jolly bodies	J:91407
	increased spleen weight	J:91407
	increased splenocyte apoptosis	J:91407
	oxidative stress	J:86725, J:91407, J:122195, J:130473
	poikilocytosis	J:91407
	reticulocytosis	J:91407
	schistocytosis	J:91407
	spongiform encephalopathy	J:122195
	thrombocytopenia	J:91407
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk involves: 129X1/SvJ * C57BL	enlarged lung	J:112943
	increased physiological sensitivity to xenobiotic	J:112943
	increased susceptibility to xenobiotic induced morbidity/mortality	J:112943
	lung hemorrhage	J:112943