About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Bmp7
bone morphogenetic protein 7
MGI:103302
105 phenotypes from 9 alleles in 11 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
B6.Cg-Bmp7tm1.1Dgra
no abnormal phenotype detected J:149134
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * CBA/J
abnormal basicranium angle J:302309
abnormal basisphenoid bone morphology J:302309
abnormal face development J:302309
abnormal nasal bone morphology J:302309
abnormal neurocranium morphology J:302309
abnormal respiration J:302309
abnormal snout morphology J:302309
abnormal turbinate morphology J:302309
apnea J:302309
decreased body temperature J:302309
decreased oxygen consumption J:302309
decreased pulmonary respiratory rate J:302309
deviated nasal septum J:302309
frontal bossing J:302309
impaired exercise endurance J:302309
increased circulating hydroxyproline level J:302309
midface hypoplasia J:302309
nasal obstruction J:302309
premature death J:302309
short basicranium J:302309
short nasal bone J:302309
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Tg(Prrx1-cre)1Cjt/0
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * SJL/J
abnormal cartilage morphology J:221175
abnormal joint morphology J:221175
joint inflammation J:221175
osteoarthritis J:221175
Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
B6.Cg-Bmp7tm1.2Dgra
abnormal basioccipital bone morphology J:148972
abnormal cochlea morphology J:148972
abnormal craniofacial development J:148972
abnormal craniofacial morphology J:148972
abnormal cranium morphology J:148972
abnormal cricoid cartilage morphology J:148972
abnormal hair follicle morphology J:148972
abnormal hard palate morphology J:148972
abnormal hyoid bone morphology J:148972
abnormal lower incisor morphology J:148972
abnormal mandible morphology J:148972
abnormal maxilla morphology J:148972
abnormal maxillary shelf morphology J:148972
abnormal middle ear ossicle morphology J:148972
abnormal molar morphology J:148972
abnormal nasal capsule morphology J:148972
abnormal nasal septum cartilage morphology J:148972
abnormal semicircular canal morphology J:148972
abnormal soft palate morphology J:148972
abnormal temporal bone petrous part morphology J:148972
abnormal thyroid cartilage morphology J:148972
abnormal tooth morphology J:148972
abnormal vibrissa morphology J:148972
abnormal vibrissa number J:148972
absent cricoid cartilage J:148972
absent thyroid cartilage J:148972
absent upper incisors J:148972
anophthalmia J:148972
cleft palate J:148972
decreased molar number J:148972
exencephaly J:148972
growth retardation of molars J:148972
hair follicle outer root sheath hyperplasia J:148972
palatal shelf hypoplasia J:148972
palatal shelves fail to meet at midline J:148972
small Meckel's cartilage J:148972
Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
abnormal eye development J:149134
abnormal kidney mesenchyme morphology J:149134
abnormal lens vesicle development J:149134
abnormal renal glomerulus morphology J:149134
abnormal sternum morphology J:149134
anophthalmia J:149134
decreased fetal size J:149134
dilated renal glomerular capsule J:149134
microphthalmia J:149134
polydactyly J:149134
preweaning lethality, complete penetrance J:149134
renal hypoplasia J:149134
retina pigment epithelium atrophy J:149134
rib bifurcation J:149134
rib fusion J:149134
short rostral-caudal axis J:149134
Bmp7tm1a(EUCOMM)Hmgu/Bmp7+
C57BL/6N-Bmp7tm1a(EUCOMM)Hmgu/H
decreased erythrocyte cell number J:165965
increased mean corpuscular volume J:165965
increased monocyte cell number J:165965
Bmp7tm1Kry/Bmp7tm1Kry
involves: 129S7/SvEvBrd * C57BL/6
abnormal alisphenoid bone morphology J:30056
abnormal apical ectodermal ridge morphology J:35171
abnormal basisphenoid bone morphology J:30056
abnormal digit morphology J:35171
abnormal lens vesicle development J:30056
abnormal xiphoid process morphology J:30056
absent metanephric mesenchyme J:30056
anophthalmia J:30056
aphakia J:30056
asymmetric sternocostal joints J:30056
basisphenoid bone foramen J:30056
broad limb buds J:35171
decreased body size J:30056
decreased body weight J:30056
decreased renal glomerulus number J:30056
decreased rib number J:30056
hydroureter J:30056
polydactyly J:30056
postnatal lethality, complete penetrance J:30056
rib fusion J:30056
normal skeleton phenotype J:30056
small basisphenoid bone J:30056
small kidney J:30056
small pterygoid bone J:30056
Bmp7tm1Kry/Bmp7tm1Kry
Not Specified
normal cardiovascular system phenotype J:89237
Bmp7tm1Rob/Bmp7tm1Rob
129S-Bmp7tm1Rob
abnormal axial skeleton morphology J:30057
abnormal cranium morphology J:30057
abnormal kidney development J:30057
abnormal sternocostal joint morphology J:30057
anophthalmia J:30057
exencephaly J:30057
hydroureter J:30057
microphthalmia J:30057
neonatal lethality, incomplete penetrance J:30057
polydactyly J:30057
Bmp7tm1Rob/Bmp7tm1Rob
either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
abnormal axial skeleton morphology J:30057
abnormal cranium morphology J:30057
abnormal kidney development J:30057
abnormal sternocostal joint morphology J:30057
anophthalmia J:30057
exencephaly J:30057
hydroureter J:30057
microphthalmia J:30057
neonatal lethality, incomplete penetrance J:30057
polydactyly J:30057
Bmp7tm2Rob/Bmp7tm2Rob
involves: 129S/SvEv
abnormal kidney development J:103587
hydroureter J:103587
kidney cyst J:103587
Bmp7tm2Rob/Bmp7tm4(Bmp4)Rob
involves: 129S/SvEv
microphthalmia J:103587
Bmp7tm2Rob/Bmp7tm5(Bmp7/Bmp6)Rob
involves: 129S/SvEv
no abnormal phenotype detected J:103587
Bmp7tm3(Bmp7)Rob/Bmp7tm2Rob
involves: 129S/SvEv
no abnormal phenotype detected J:103587

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory