Zbtb7b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zbtb7b
zinc finger and BTB domain containing 7B
MGI:102755

18 phenotypes from 17 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(CD2-Zbtb7b)C8Rbo/? involves: C57BL/6	absent CD8-positive, alpha-beta T cells	J:97610
Tg(CD2-Zbtb7b)C8Rbo/? involves: C57BL/6	increased CD4-positive, alpha-beta T cell number	J:97610
Tg(CD4-Zbtb7b*,-GFP)1Itan/? Not Specified	no abnormal phenotype detected	J:141142
Zbtb7b^hd/Zbtb7b^hd involves: 129/Sv * BALB/c * C3H * C57BL/6	abnormal CD4-positive T cell differentiation	J:48734
	absent CD4-positive, alpha-beta T cells	J:48734
	increased CD8-positive, alpha-beta T cell number	J:48734
	reduced female fertility	J:48734
Zbtb7b^hpls/Zbtb7b^hpls involves: C57BL/6JAnu	abnormal humoral immune response	J:104190
Zbtb7b^hpls/Zbtb7b^hpls involves: C57BL/6JAnu	decreased CD4-positive, alpha-beta T cell number	J:104190
Zbtb7b^tm1.1Rbo/Zbtb7b^tm1.1Rbo Not Specified	abnormal CD8-positive, alpha-beta T cell number	J:141145
	abnormal T cell differentiation	J:141145
	decreased CD4-positive, alpha-beta T cell number	J:141145
Zbtb7b^tm1.1Skok/Zbtb7b^tm1.1Skok involves: 129/Sv * C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:169841
Zbtb7b^tm1Itan/Zbtb7b^tm1Tani involves: 129 * C57BL/6	abnormal CD4-positive, alpha beta T cell morphology	J:141142
	abnormal CD4-positive, alpha-beta T cell physiology	J:141142
	decreased CD4-positive, alpha-beta T cell number	J:141142
	increased CD8-positive, alpha-beta T cell number	J:141142
	increased double-negative T cell number	J:141142
Zbtb7b^tm1Itan/Zbtb7b^tm2Itan involves: 129 * C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:141142
	increased CD8-positive, alpha-beta T cell number	J:141142
	increased double-negative T cell number	J:141142
Zbtb7b^tm1Litt/Zbtb7b^tm1.2Litt involves: C57BL/6	abnormal double-positive T cell morphology	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
	increased CD8-positive, alpha-beta T cell number	J:141144
	increased interferon-gamma secretion	J:141144
Zbtb7b^tm1Tani/Zbtb7b^tm1Tani involves: 129 * C57BL/6	increased double-negative T cell number	J:141142
Zbtb7b^tm2Itan/Zbtb7b⁺ involves: 129 * C57BL/6	no abnormal phenotype detected	J:141142
Zbtb7b^tm2Litt/Zbtb7b^tm1.2Litt involves: 129P2/OlaHsd	decreased CD4-positive, alpha-beta T cell number	J:141144
Zbtb7b^tm2Litt/Zbtb7b^tm1.2Litt Tg(Lck-cre)1Cwi/? involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
Zbtb7b^tm2Litt/Zbtb7b^tm2Litt involves: 129P2/OlaHsd * C57BL/6 * FVB/N	absent CD4-positive, alpha-beta T cells	J:141519
Zbtb7b^tm2Tani/Zbtb7b⁺ Not Specified	decreased CD8-positive, alpha-beta T cell number	J:131081
Zbtb7b^tm3Itan/Zbtb7b^tm3Itan Not Specified	no abnormal phenotype detected	J:141142
Zbtb7b^tm4.1Itan/Zbtb7b^tm4.1Itan Not Specified	decreased CD4-positive, alpha-beta T cell number	J:193321
Zbtb7b^tm4.1Itan/Zbtb7b^tm4.1Itan Not Specified	increased CD8-positive, alpha-beta T cell number	J:193321
Zbtb7b^tm6.1Itan/Zbtb7b^tm6.1Itan Tg(Cd4-cre)1Cwi/? involves: C57BL/6 * DBA/2	decreased CD8-positive, alpha-beta T cell number	J:195348
Zbtb7b^tm6.1Itan/Zbtb7b^tm6.1Itan Tg(Cd8a-cre)1Itan/? involves: C57BL/6	normal immune system phenotype	J:195348
Zbtb7b^tm7Itan/Zbtb7b^tm7Itan Not Specified	decreased CD4-positive, alpha-beta T cell number	J:195348

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