Mapping Data Summary

• Symbol: Tcrb
• Name: T cell receptor beta chain
• ID: MGI:98578
• Chromosome: 6

68 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross	6	J:1187 Bahary N, et al., Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome. Genomics. 1992 Jul;13(3):761-9
CROSS	Cross Type: Backcross	6	J:3321 Bahary N, et al., Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics. 1991 Sep;11(1):33-47
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:35238 Ben-Arie N, et al., Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. Hum Mol Genet. 1996 Sep;5(9):1207-16
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:35238 Ben-Arie N, et al., Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. Hum Mol Genet. 1996 Sep;5(9):1207-16
CROSS	Cross Type: Backcross	6	J:8525 Bucan M, et al., Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7. EMBO J. 1986 Nov;5(11):2899-905
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:45591 Chidambaram A, et al., Chromosomal localization of the human and murine orthologues of the Drosophila smoothened gene. Genomics. 1998 Nov 1;53(3):416-7
CROSS	Cross Type: Backcross	6	J:8024 D'Hoostelaere LA, et al., Localization of CT beta and C kappa on mouse chromosome 6. Immunogenetics. 1985;22(3):277-83
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:15505 Dean M, et al., Chromosomal localization of the met proto-oncogene in the mouse and cat genome. Genomics. 1987 Oct;1(2):167-73
CROSS	Cross Type: Backcross	6	J:15505 Dean M, et al., Chromosomal localization of the met proto-oncogene in the mouse and cat genome. Genomics. 1987 Oct;1(2):167-73
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:35627 Farris AD, et al., Genes for murine Y1 and Y3 Ro RNAs have class 3 RNA polymerase III promoter structures and are unlinked on mouse chromosome 6. Gene. 1996 Sep 26;174(1):35-42
CROSS	Cross Type: Backcross	6	J:1908 Friedman JM, et al., Molecular mapping of the mouse ob mutation. Genomics. 1991 Dec;11(4):1054-62
CROSS	Cross Type: Backcross	6	J:18473 Gariboldi M, et al., Comparative mapping of the actin-binding protein 280 genes in human and mouse. Genomics. 1994 May 15;21(2):428-30
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:12846 Godfrey P, et al., GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function. Nat Genet. 1993 Jul;4(3):227-32
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:62532 Gray TA, et al., The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system. Genomics. 2000 May 15;66(1):76-86
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:62532 Gray TA, et al., The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system. Genomics. 2000 May 15;66(1):76-86
CROSS	Cross Type: Backcross Mapping Panel: Seldin	6	J:32076 Guthridge MA, et al., Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts. Oncogene. 1996 Mar 21;12(6):1267-78
CROSS	Cross Type: Backcross Mapping Panel: Kozak Skive	6	J:17608 Hake LE, et al., The genes encoding the somatic and testis-specific isotypes of the mouse cytochrome c genes map to paralogous regions of chromosomes 6 and 2. Genomics. 1994 Apr;20(3):503-5
CROSS	Cross Type: Backcross	6	J:17608 Hake LE, et al., The genes encoding the somatic and testis-specific isotypes of the mouse cytochrome c genes map to paralogous regions of chromosomes 6 and 2. Genomics. 1994 Apr;20(3):503-5
CROSS	Cross Type: Intercross	6	J:12780 Jones JM, et al., mnd2: a new mouse model of inherited motor neuron disease. Genomics. 1993 Jun;16(3):669-77
CROSS	Cross Type: Backcross	6	J:16150 Klocke R, et al., Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal. Genomics. 1993 Dec;18(3):568-74
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:18647 Ko MS, et al., Genetic mapping of 40 cDNA clones on the mouse genome by PCR. Mamm Genome. 1994 Jun;5(6):349-55
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:18647 Ko MS, et al., Genetic mapping of 40 cDNA clones on the mouse genome by PCR. Mamm Genome. 1994 Jun;5(6):349-55
CROSS	Cross Type: Backcross	6	J:22835 Kozak CA, et al., Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1). Genomics. 1995 Jan 1;25(1):66-72
CROSS	Cross Type: Backcross Mapping Panel: Kozak Skive	6	J:22835 Kozak CA, et al., Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1). Genomics. 1995 Jan 1;25(1):66-72
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:19453 Kumar S, et al., Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev. 1994 Jul 15;8(14):1613-26
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:69072 Lee S, et al., The mouse Kell blood group gene (Kel): cDNA sequence, genomic organization, expression, and enzymatic function. Immunogenetics. 2000 Nov;52(1-2):53-62
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:3474 Li YS, et al., Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization. J Biol Chem. 1992 Dec 25;267(36):26011-6
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:20038 Lueders KK, et al., Mapping of mouse intracisternal A-particle proviral markers in an interspecific backcross. Mamm Genome. 1994 Aug;5(8):473-8
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:45742 Marazziti D, et al., Molecular cloning and chromosomal localization of the mouse Gpr37 gene encoding an orphan G-protein-coupled peptide receptor expressed in brain and testis. Genomics. 1998 NOV 1;53(3):315-324
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:45742 Marazziti D, et al., Molecular cloning and chromosomal localization of the mouse Gpr37 gene encoding an orphan G-protein-coupled peptide receptor expressed in brain and testis. Genomics. 1998 NOV 1;53(3):315-324
CROSS	Cross Type: Backcross Mapping Panel: Seldin	6	J:51382 Matsui M, et al., Mapping of five subtype genes for Muscarinic acetylcholine receptor to mouse chromosomes. Genes Genet Syst. 1998;73(1):15-21
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	6	J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	6	J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
CROSS	Cross Type: Backcross	6	J:8820 Mock BA, et al., A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6. Genetics. 1987 Aug;116(4):607-12
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:29922 Moon C, et al., The mouse aquaporin-1 gene. Genomics. 1995 Nov 20;30(2):354-7
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:31569 Nakamura T, et al., Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias [see comments]. Nat Genet. 1996 Feb;12(2):149-53
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:9924 Regnier DC, et al., Identification of two murine loci homologous to the v-cbl oncogene. J Virol. 1989 Sep;63(9):3678-82
CROSS	Cross Type: Intercross	6	J:7941 Roehm NW, et al., The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol. 1985 Sep;135(3):2176-82
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:26141 Roller ML, et al., Localization of the thyrotropin-releasing hormone gene, Trh, on mouse chromosome 6. Mamm Genome. 1995 Jun;6(6):443-4
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:18140 Rowe LB, et al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource [published erratum appears in Mamm Genome 1994 Jul;5(7):463]. Mamm Genome. 1994 May;5(5):253-74
CROSS	Cross Type: Backcross Mapping Panel: Seldin	6	J:9125 Seldin MF, et al., Mapping of the Ly-4 (L3T4) T-cell differentiation antigen on mouse chromosome 6 by the use of RFLPs in an interspecific cross. Immunogenetics. 1988;27(5):396-8
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:79792 Simckes AM, et al., Chromosomal localization of three vacuolar-H(+)-ATPase 16 kDa subunit (ATP6V0C) genes in the murine genome. Cytogenet Genome Res. 2002;97(1-2):111-5
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:11120 Siracusa LD, et al., Identification and applications of repetitive probes for gene mapping in the mouse. Genetics. 1991 Jan;127(1):169-79
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:11320 Siracusa LD, et al., Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome. Genomics. 1991 Jun;10(2):313-26
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSB)	6	J:30577 Sorenson RC, et al., The genetic mapping and gene structure of mouse paraoxonase/arylesterase. Genomics. 1995 Dec 10;30(3):431-8
CROSS	Cross Type: Backcross	6	J:752 Steinmeyer K, et al., Inactivation of muscle chloride channel by transposon insertion in myotonic mice. Nature. 1991 Nov 28;354(6351):304-8
CROSS	Cross Type: Backcross	6	J:752 Steinmeyer K, et al., Inactivation of muscle chloride channel by transposon insertion in myotonic mice. Nature. 1991 Nov 28;354(6351):304-8
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	6	J:21914 Wen XY, et al., Genetic mapping of two mouse homeobox genes Tlx-1 and Tlx-2 to murine chromosomes 19 and 6. Genomics. 1994 Nov 15;24(2):388-90
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	6	J:22084 Yamin M, et al., Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene. Endocrinology. 1994 Dec;135(6):2635-43
HYBRID		6	J:7499 Caccia N, et al., The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans. Cell. 1984 Jul;37(3):1091-9
HYBRID		6	J:7557 Lee NE, et al., Murine T cell receptor beta chain is encoded on chromosome 6. J Exp Med. 1984 Sep 1;160(3):905-13
IN SITU	Band: A-C	6	J:7499 Caccia N, et al., The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans. Cell. 1984 Jul;37(3):1091-9
RI	RI/RC Set: CXJ	6	J:7825 Epstein R, et al., Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 1;161(5):1219-24
RI	RI/RC Set: CXJ	6	J:16092 Malek TR, et al., The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15. Immunogenetics. 1993;38(2):154-6
RI	RI/RC Set: CXJ	6	J:8573 Melvold RW, et al., Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromoome 6. J Immunol. 1987 Mar 1;138(5):1429-33
RI	RI/RC Set: OXA	6	J:8820 Mock BA, et al., A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6. Genetics. 1987 Aug;116(4):607-12
RI	RI/RC Set: AKXL	6	J:7941 Roehm NW, et al., The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol. 1985 Sep;135(3):2176-82
RI	RI/RC Set: OXA	6	J:17755 ten Berg R, SD patterns of a series of OXA recombinant inbred strains. Mouse News Lett. 1989;84:102-104
TEXT		6	J:164867 Spicuglia S, et al., Epigenetic control of Tcrb gene rearrangement. Semin Immunol. 2010 Dec;22(6):330-6
TEXT-Genetic Cross		6	J:29406 Davies PO, et al., An anchored molecular map of mouse chromosome 6 with an analysis of interference. Mamm Genome. 1995 Oct;6(10):738-40
TEXT-Genetic Cross		6	J:29218 Manenti G, et al., Different susceptibility to lung tumorigenesis in mice with an identical Kras2 intron 2. Genomics. 1995 Sep 20;29(2):438-44
TEXT-QTL		6	J:108420 Hamano Y, et al., Genetic dissection of vasculitis, myeloperoxidase-specific antineutrophil cytoplasmic autoantibody production, and related traits in spontaneous crescentic glomerulonephritis-forming/Kinjoh mice. J Immunol. 2006 Mar 15;176(6):3662-73
TEXT-QTL		6	J:71668 Hardy CL, et al., Identification of quantitative trait loci controlling activation of TRBV4 CD8+ T cells during murine gamma-herpesvirus-induced infectious mononucleosis. Immunogenetics. 2001 Jul;53(5):395-400
TEXT-QTL		6	J:11074 Hirose S, et al., Contribution of the gene linked to the T cell receptor beta chain gene complex of NZW mice to the autoimmunity of (NZB x NZW)F1 mice. Eur J Immunol. 1991 Mar;21(3):823-6
TEXT-QTL		6	J:4933 Sudweeks JD, et al., Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3700-4
TEXT-QTL		6	J:4933 Sudweeks JD, et al., Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3700-4