Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT16
  • Mouse genes Wnt16
  • Rat genes Wnt16
  • Zfish genes wnt16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005737	cytoplasm	WNT16	IDA		Human	PMID:17200136
Cellular Component	GO:0005615	extracellular space	WNT16	IDA		Human	PMID:10500199
Biological Process	GO:0030282	bone mineralization	wnt16	IMP	ZFIN:ZDB-GENO-220831-5	Zfish	PMID:33778326
Biological Process	GO:0030282	bone mineralization	wnt16	IMP	ZFIN:ZDB-GENO-220831-4	Zfish	PMID:33778326
Biological Process	GO:0060349	bone morphogenesis	wnt16	IMP	ZFIN:ZDB-GENO-230223-1	Zfish	PMID:34206401
Biological Process	GO:1990523	bone regeneration	wnt16	IMP	ZFIN:ZDB-GENO-220831-5	Zfish	PMID:33778326
Biological Process	GO:1990523	bone regeneration	wnt16	IMP	ZFIN:ZDB-GENO-220901-4	Zfish	PMID:33778326
Biological Process	GO:1990523	bone regeneration	wnt16	IMP	ZFIN:ZDB-GENO-220901-3	Zfish	PMID:33778326
Biological Process	GO:1990523	bone regeneration	wnt16	IMP	ZFIN:ZDB-GENO-220831-4	Zfish	PMID:33778326
Biological Process	GO:0046849	bone remodeling	Wnt16	IMP	MGI:MGI:5467557	Mouse	PMID:22792071
Biological Process	GO:0060317	cardiac epithelial to mesenchymal transition	Wnt16	IMP		Mouse	PMID:19156209
Biological Process	GO:0072498	embryonic skeletal joint development	wnt16	IMP	ZFIN:ZDB-MRPHLNO-120329-1	Zfish	PMID:28684625
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	wnt16	IMP	ZFIN:ZDB-MRPHLNO-120329-2	Zfish	PMID:25230933
Biological Process	GO:0060218	hematopoietic stem cell differentiation	wnt16	IMP	ZFIN:ZDB-MRPHLNO-120329-1,ZFIN:ZDB-MRPHLNO-120329-2	Zfish	PMID:21654806
Biological Process	GO:0030216	keratinocyte differentiation	WNT16	IMP		Human	PMID:17200136
Biological Process	GO:0043616	keratinocyte proliferation	WNT16	IMP		Human	PMID:17200136
Biological Process	GO:0060548	negative regulation of cell death	WNT16	IMP		Human	PMID:17200136
Biological Process	GO:0007219	Notch signaling pathway	wnt16	IGI	ZFIN:ZDB-GENO-070214-1,ZFIN:ZDB-MRPHLNO-120329-1,ZFIN:ZDB-MRPHLNO-120329-2	Zfish	PMID:21654806
Biological Process	GO:0090403	oxidative stress-induced premature senescence	WNT16	IMP		Human	PMID:19951988
Biological Process	GO:0010628	positive regulation of gene expression	WNT16	IMP		Human	PMID:16007226
Biological Process	GO:0046330	positive regulation of JNK cascade	WNT16	IMP		Human	PMID:17200136
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	WNT16	IMP		Human	PMID:19951988
Biological Process	GO:0030500	regulation of bone mineralization	wnt16	IMP	ZFIN:ZDB-GENO-230223-1	Zfish	PMID:34206401
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	wnt16	IMP	ZFIN:ZDB-GENO-220901-10	Zfish	PMID:33778326
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	wnt16	IMP	ZFIN:ZDB-GENO-220901-9	Zfish	PMID:33778326
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	wnt16	IMP	ZFIN:ZDB-MRPHLNO-120329-2	Zfish	PMID:25428693
Biological Process	GO:0090399	replicative senescence	WNT16	IMP		Human	PMID:19951988

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern