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Wnt16
Gene Detail
 Symbol
Name
ID
Wnt16
wingless-type MMTV integration site family, member 16
MGI:2136018
Synonyms E130309I19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 6
9.22 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:22288227-22298522 bp, + strand
From VEGA annotation of GRCm38

  10296 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62175  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt16

Human
homologs
Human Homolog WNT16, wingless-type MMTV integration site family, member 16
NCBI Gene ID 51384
neXtProt AC  NX_Q9UBV4
Human Chr (Location)  7q31; chr7:121325367-121341104 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased bone mineral density, cortical bone thickness and bone strength.
 
Interactions
Wnt16 interacts with 314 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process bone remodeling, cardiac epithelial to mesenchymal transition, ...
Component cytoplasm, extracellular region, ...
Function frizzled binding, receptor binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (33 records)
Data Summary: Results (380)    Tissues (355)    Images (27)
Theiler Stages: 1, 2, 3, 5, 8, 9, 10, 11, 13, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 28
Assay TypeResults
RNA in situ 358
Northern blot 4
RT-PCR 18
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) Genomic(1) cDNA(11) Primer pair(5) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026889 (Evidence)
Ensembl Gene ModelENSMUSG00000029671 (Evidence)
Entrez Gene93735 (Evidence)
UniGene137403
DFCITC1590558, TC1610123
DoTSDT.101716642, DT.91581325, DT.94155881
NIA Mouse Gene IndexU006585
Consensus CDS ProjectCCDS19936.1
International Mouse Knockout Project StatusWnt16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026889 VEGA Gene Model | MGI Sequence Detail 10296 C57BL/6J ±  kb
transcript OTTMUST00000066501 VEGA | MGI Sequence Detail 1663 Not Applicable 
polypeptide OTTMUSP00000033330 VEGA | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(138 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR013304 Wnt-16 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017439 protein Wnt-16
References (Earliest) J:57926 McWhirter JR, et al., Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11464-9
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(62)
Other
accession IDs
MGI:2444753

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory