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Gene Ontology Browser
Term Detail
GO term:replicative senescence
GO id:GO:0090399
Definition:A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell aging
                                        is-acellular senescence +
                                        is-achronological cell aging +
                                        negatively-regulatesnegative regulation of cell aging +
                                        part-ofnucleolar fragmentation +
                                        positively-regulatespositive regulation of cell aging +
                                        part-ofprogressive alteration of chromatin involved in cell aging +
                                        regulatesregulation of cell aging +
                                        is-areplicative cell aging +
                                        is-areplicative senescence [GO:0090399] (8 genes, 8 annotations)


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-aaging
                                        is-acell aging
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence [GO:0090399] (8 genes, 8 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell aging
                                        is-acellular senescence +
                                        is-achronological cell aging +
                                        negatively-regulatesnegative regulation of cell aging +
                                        part-ofnucleolar fragmentation +
                                        positively-regulatespositive regulation of cell aging +
                                        part-ofprogressive alteration of chromatin involved in cell aging +
                                        regulatesregulation of cell aging +
                                        is-areplicative cell aging +
                                        is-areplicative senescence [GO:0090399] (8 genes, 8 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-aaging
                                        is-acell aging
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence [GO:0090399] (8 genes, 8 annotations)


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory