Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS16
  • Mouse genes Vps16
  • Rat genes Vps16
  • Zfish genes vps16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Vps16	IDA		Mouse	PMID:14668490
Molecular Function	GO:0051015	actin filament binding	Vps16	IDA		Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9H270	Human	PMID:11382755
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9P253	Human	PMID:11382755
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:20190753
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:23901104
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9H270	Human	PMID:23901104
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9P253	Human	PMID:23901104
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:P56962	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q8WUH2	Human	PMID:25266290
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:25783203
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9P253	Human	PMID:25783203
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q8WUH2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9H270	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q9P253	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:28013294
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:29778605
Molecular Function	GO:0005515	protein binding	VPS16	IPI	UniProtKB:Q96AX1	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Vps16	IPI	UniProtKB:Q9H9C1	Mouse	MGI:MGI:4441246|PMID:19109425
Molecular Function	GO:0005515	protein binding	Vps16	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Vps16	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Cellular Component	GO:0005884	actin filament	Vps16	IDA		Mouse	PMID:14668490
Cellular Component	GO:0030123	AP-3 adaptor complex	Vps16	IDA		Mouse	MGI:MGI:5645203|PMID:21411634
Cellular Component	GO:0030424	axon	Vps16	IDA		Rat	PMID:14732470|RGD:1554271
Cellular Component	GO:0030136	clathrin-coated vesicle	Vps16	IDA		Mouse	MGI:MGI:5645203|PMID:21411634
Cellular Component	GO:0033263	CORVET complex	Vps16	IDA		Mouse	MGI:MGI:5645189|PMID:25266290
Cellular Component	GO:0005769	early endosome	VPS16	IDA		Human	PMID:19109425
Cellular Component	GO:0005769	early endosome	Vps16	IDA		Mouse	PMID:14668490
Cellular Component	GO:0031901	early endosome membrane	Vps16	IDA		Mouse	MGI:MGI:5645203|PMID:21411634
Cellular Component	GO:0005768	endosome	Vps16	IDA		Rat	PMID:14668490|RGD:1549677
Cellular Component	GO:0030897	HOPS complex	VPS16	IDA		Human	PMID:19109425
Cellular Component	GO:0030897	HOPS complex	VPS16	IDA		Human	PMID:23901104
Cellular Component	GO:0030897	HOPS complex	VPS16	IDA		Human	PMID:25783203
Cellular Component	GO:0005770	late endosome	VPS16	IDA		Human	PMID:11382755
Cellular Component	GO:0005770	late endosome	VPS16	IDA		Human	PMID:19109425
Cellular Component	GO:0005765	lysosomal membrane	VPS16	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	VPS16	IDA		Human	PMID:11382755
Cellular Component	GO:0005764	lysosome	VPS16	IDA		Human	PMID:21802320
Cellular Component	GO:0043025	neuronal cell body	Vps16	IDA		Rat	PMID:14732470|RGD:1554271
Cellular Component	GO:0098793	presynapse	Vps16	IDA		Rat	PMID:17027648|RGD:13702280
Cellular Component	GO:0098793	presynapse	Vps16	IMP		Rat	PMID:17027648|RGD:13702280
Cellular Component	GO:0055037	recycling endosome	VPS16	IDA		Human	PMID:19109425
Biological Process	GO:0097352	autophagosome maturation	VPS16	IMP		Human	PMID:25783203
Biological Process	GO:0008333	endosome to lysosome transport	VPS16	IMP		Human	PMID:25783203
Biological Process	GO:0007040	lysosome organization	vps16	IMP	ZFIN:ZDB-CRISPR-220308-1	Zfish	PMID:33938619
Biological Process	GO:0042552	myelination	vps16	IMP	ZFIN:ZDB-CRISPR-220308-1	Zfish	PMID:33938619
Biological Process	GO:0046718	viral entry into host cell	Vps16	IMP		Mouse	PMID:24550300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern