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Vps16 Gene Detail
Summary
  • Symbol
    Vps16
  • Name
    VSP16 CORVET/HOPS core subunit
  • Synonyms
    1810074M16Rik, MGC:7352
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136772
    NCBI Gene: 80743
Location & Maps
more
  • Sequence Map
    Chr2:130424339-130444269 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19931 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 63.22 cM, cytoband F3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    VPS16, VPS16, CORVET/HOPS core subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VPS16, VPS16, CORVET/HOPS core subunit
    Orthology source: HomoloGene
  • Synonyms
    hVPS16
  • Links
    NCBI Gene ID: 64601
    neXtProt AC: NX_Q9H269

  • Chr Location
    20p13; chr20:2840697-2866732 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Vps16
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015524 VEGA Gene Model | MGI Sequence Detail 19931 C57BL/6J ±  kb
transcript OTTMUST00000036861 VEGA | MGI Sequence Detail 3161 Not Applicable  
polypeptide OTTMUSP00000016541 VEGA | MGI Sequence Detail 839 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    130 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000017323 vacuolar protein sorting-associated protein 16
  • InterPro Domains
    IPR016534 Vacuolar protein sorting-associated protein 16
    IPR006925 Vps16, C-terminal
    IPR006926 Vps16, N-terminal
Molecular
Reagents
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  • All nucleic 121
    cDNA 121

    Microarray probesets 3
Other
Accession IDs
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MGI:1917055
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:222663 Perini ED, et al., Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations. Traffic. 2014 Dec;15(12):1366-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory