| GO term: | actin filament |
| Synonym: | microfilament |
| GO id: | GO:0005884 |
| Definition: | A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. |
| Number of paths to term: | 24 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcellcell partintracellularintracellular partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcellcell partintracellular partintracellular organelleintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcellcell partintracellular partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellularintracellular partintracellular organelleintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellularintracellular partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellular partintracellular organelleintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentcell partintracellular partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentmacromolecular complexprotein complex1,3-beta-D-glucan synthase complex1-alkyl-2-acetylglycerophosphocholine esterase complex3-isopropylmalate dehydratase complex3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex3-methylcrotonyl-CoA carboxylase complex, mitochondrial3-phenylpropionate dioxygenase complex4-aminobutyrate transaminase complex5-lipoxygenase complex6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex6-phosphofructokinase complex7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex[Ni-Fe] hydrogenase complexABIN2-NFKB1-MAP3K8 complexacetate CoA-transferase complex +acetolactate synthase complexacetyl-CoA carboxylase complex +acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complexactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactivin complex +ADPG pyrophosphorylase complex +AIM2 inflammasome complexalkyl hydroperoxide reductase complexalpha DNA polymerase:primase complexalpha,alpha-trehalose-phosphate synthase complex (UDP-forming)alpha1-beta1 integrin-alpha3(VI) complexalpha1-beta1 integrin-tissue transglutaminase complexalpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complexalpha11-beta1 integrin-collagen type I complexalpha2-beta1 integrin-alpha3(VI) complexalpha2-beta1 integrin-CD47 complexalpha2-beta1 integrin-chondroadherin complexalpha3-beta1 integrin-basigin complexalpha3-beta1 integrin-CD151 complexalpha3-beta1 integrin-CD63 complexalpha3-beta1 integrin-thrombospondin complexalpha3-beta1 integrin-tissue transglutaminase complexalpha4-beta1 integrin-CD47 complexalpha4-beta1 integrin-CD53 complexalpha4-beta1 integrin-CD63 complexalpha4-beta1 integrin-CD81 complexalpha4-beta1 integrin-CD82 complexalpha4-beta1 integrin-JAM2 complexalpha4-beta1 integrin-paxillin complexalpha4-beta1 integrin-thrombospondin-1 complexalpha4-beta1 integrin-thrombospondin-2 complexalpha4-beta4 integrin-EMILIN-1 complexalpha5-beta1 integrin-endostatin complexalpha5-beta1 integrin-fibronectin-NOV complexalpha5-beta1 integrin-fibronectin-tissue transglutaminase complexalpha5-beta1 integrin-LPP3 complexalpha5-beta1 integrin-osteopontin complexalpha5-beta1 integrin-tissue transglutaminase complexalpha5-beta5-fibronectin-SFRP2 complexalpha6-beta1 integrin-CD151 complexalpha6-beta1 integrin-CYR61 complexalpha6-beta4 integrin-CD151 complexalpha6-beta4 integrin-CD9 complexalpha6-beta4 integrin-Fyn complexalpha6-beta4 integrin-laminin 5 complexalpha6-beta4 integrin-Shc-Grb2 complexalpha7-beta1 integrin-CD151 complexalpha7-beta1 integrin-focal adhesion kinase complexalpha7-beta1 integrin-laminin alpha-2 complexalpha7-beta1 integrin-nicotinamide riboside kinase complexalpha9-beta1 integrin-ADAM1 complexalpha9-beta1 integrin-ADAM12 complexalpha9-beta1 integrin-ADAM15 complexalpha9-beta1 integrin-ADAM2 complexalpha9-beta1 integrin-ADAM3 complexalpha9-beta1 integrin-ADAM8 complexalpha9-beta1 integrin-ADAM9 complexalpha9-beta1 integrin-osteopontin complexalpha9-beta1 integrin-tenascin complexalpha9-beta1 integrin-thrombospondin-1 complexalpha9-beta1 integrin-vascular cell adhesion molecule-1 complexalpha9-beta1 integrin-VEGF-A complexalpha9-beta1 integrin-VEGF-C complexalpha9-beta1 integrin-VEGF-D complexalphaE-beta7 integrin-E-cadherin complexalphaIIb-beta3 integrin-CD47-FAK complexalphaIIb-beta3 integrin-CD47-Src complexalphaIIb-beta3 integrin-CD9 complexalphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complexalphaIIb-beta3 integrin-CIB complexalphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complexalphaIIb-beta3 integrin-ICAM-4 complexalphaIIb-beta3 integrin-talin complexalphaM-beta2 integrin-CD63 complexalphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complexalphaPDGFR-SHP-2 complexalphav-beta1 integrin-osteopontin complexalphav-beta3 integrin-ADAM15 complexalphav-beta3 integrin-ADAM23 complexalphav-beta3 integrin-CD47 complexalphaV-beta3 integrin-CD47-FCER2 complexalphaV-beta3 integrin-CD98 complexalphav-beta3 integrin-collagen alpha3(VI) complexalphaV-beta3 integrin-EGFR complexalphaV-beta3 integrin-gelsolin complexalphav-beta3 integrin-HMGB1 complexalphav-beta3 integrin-IGF-1-IGF1R complexalphaV-beta3 integrin-laminin alpha-4 complexalphaV-beta3 integrin-LPP3 complexalphaV-beta3 integrin-NOV complexalphav-beta3 integrin-osteopontin complexalphaV-beta3 integrin-paxillin-Pyk2 complexalphav-beta3 integrin-PKCalpha complexalphav-beta3 integrin-thrombospondin complexalphaV-beta3 integrin-tissue transglutaminase complexalphaV-beta3 integrin-tumstatin complexalphav-beta3 integrin-vitronectin complexalphav-beta5 integrin-osteopontin complexalphav-beta5 integrin-vitronectin complexalphaV-beta6 integrin-osteopontin complexalphaV-beta6 integrin-TGFbeta-3 complexalphaV-beta8 integrin-MMP14-TGFbeta-1 complexalphaX-beta2 integrin-ICAM-4 complexaminoacyl-tRNA synthetase multienzyme complexaminodeoxychorismate synthase complexAMP-activated protein kinase complexanaerobic ribonucleoside-triphosphate reductase complexangiogenin-PRI complexanthranilate synthase complexAP-type membrane coat adaptor complex +APC-IQGAP complexAPC-IQGAP1-Cdc42 complexAPC-IQGAP1-CLIP-170 complexAPC-IQGAP1-Rac1 complexAPC-tubulin-IQGAP1 complexapolipoprotein B mRNA editing enzyme complexapoptosomeArp2/3 protein complexaspartate carbamoyltransferase complexaster +ASTRA complexAtg12-Atg5-Atg16 complexAtg1p signaling complexATP-binding cassette (ABC) transporter complex +ATR-ATRIP complexauxin efflux carrier complexaxonemal heterotrimeric kinesin-II complexB800-820 antenna complexB800-850 antenna complexB875 antenna complexBam protein complexBBSomeBcl-2 family protein complex +Bcl3-Bcl10 complexbeta-catenin destruction complexbeta-galactosidase complexbiotin carboxylase complex +BLOC complex +BRCA1-A complexBRCA1-B complexBRCA1-C complexBRCA1-Rad51 complexBRCA2-BRAF35 complexBRCA2-MAGE-D1 complexBRISC complexbursicon neuropeptide hormone complexCAAX-protein geranylgeranyltransferase complexCAF-1 complexCAK-ERCC2 complexcalcium- and calmodulin-dependent protein kinase complexcAMP-dependent protein kinase complexcarbamoyl-phosphate synthase complexcarboxy-terminal domain protein kinase complex +caspase complexcatenin complexcatenin-TCF7L2 complex +cation-transporting ATPase complex +caveolar macromolecular signaling complexCBF3 complexCBM complexCCR4-NOT complex +CCR4-NOT core complexCD19-Vav-PIK3R1 complexCD20-Lck-Fyn complexCD20-Lck-Lyn-Fyn complexCdc42 GTPase complexCdc48p-Npl4p-Ufd1p AAA ATPase complexCdc48p-Npl4p-Vms1p AAA ATPase complexcell envelope Sec protein transport complexcellulose synthase complex +centralspindlin complexCFTR-NHERF-ezrin complexchaperonin ATPase complexchaperonin-containing T-complexcheckpoint clamp complexchloroplast ATP synthase complexchloroplast outer membrane transloconchromatin silencing complex +chromosome segregation-directing complexCIA complexcitrate lyase complexclassical-complement-pathway C3/C5 convertase complexclathrin complexCNTFR-CLCF1 complexCoB-CoM heterodisulfide reductase complexcohesin complex +cohesin core heterodimerCOMA complexcomplement component C1 complexcondensed chromosome inner kinetochore +condensed chromosome outer kinetochore +condensin complex +condensin core heterodimerconnexon complexcontractile vacuole porecore mediator complexCORVET complexCRD-mediated mRNA stability complexcreatine kinase complex +CRLF-CLCF1 complexCSK-GAP-A.p62 complexCtf18 RFC-like complexCUGBP1-eIF2 complexCURI complexCVT complexcyclic-nucleotide phosphodiesterase complexcyclin-dependent protein kinase activating kinase holoenzyme complexcyclin-dependent protein kinase holoenzyme complex +cysteine synthase complexcytochrome b6f complexcytochrome complexcytochrome o ubiquinol oxidase complexcytosolic tRNA wobble base thiouridylase complexD-amino-acid dehydrogenase complexDbf4-dependent protein kinase complexDBIRD complexdeath-inducing signaling complex +decaprenyl diphosphate synthase complex +Delta1 complexdimethyl sulfoxide reductase complexDNA helicase complex +DNA ligase III-XRCC1 complexDNA ligase IV complexDNA polymerase complex +DNA polymerase III, beta sliding clamp processivity factor complexDNA polymerase III, clamp loader chi/psi subcomplexDNA polymerase III, clamp loader complex +DNA polymerase III, core complex +DNA polymerase III, proofreading complexDNA recombinase mediator complex +DNA replication factor A complexDNA replication factor C complex +DNA replication factor C core complexDNA topoisomerase complex (ATP-hydrolyzing)DNA topoisomerase IV complexDNA-dependent protein kinase complexDsc E3 ubiquitin ligase complexDsl1p complexDUBm complexDxr protein complexdystrobrevin complexdystroglycan complex +dystrophin-associated glycoprotein complex +E.F.G complexEcsit-NDUFAF1 complexegasyn-beta-glucuronidase complexEGFR-Grb2-Sos complexEGFR-Shc-Grb2-Sos complexEGO complexeisosome filamentEKC/KEOPS complexelectron transfer flavoprotein complex +Elg1 RFC-like complexElongator holoenzyme complexendopeptidase Clp complex +endoplasmic reticulum chaperone complexendoplasmic reticulum Sec complex +endosomal scaffold complexenterobactin synthetase complexER membrane insertion complex +ER membrane protein complexERMES complexESCRT I complexESCRT II complexESCRT III complexESCRT-0 complexethanolamine ammonia-lyase complexeukaryotic translation elongation factor 1 complexeukaryotic translation initiation factor 2 complexeukaryotic translation initiation factor 2B complexeukaryotic translation initiation factor 3 complex +eukaryotic translation initiation factor 4F complexexcinuclease repair complexexocystexodeoxyribonuclease V complexexodeoxyribonuclease VII complexexomer complexexon-exon junction complexexosome (RNase complex) +F-actin capping protein complex +FAl1-SGD1 complexFANCM-MHF complexFanconi anaemia nuclear complexFAR/SIN/STRIPAK complexfatty acid beta-oxidation multienzyme complex +fatty acid elongase complexfatty acid synthase complexfatty-acyl-CoA synthase complexFc receptor complex +ferredoxin hydrogenase complexferredoxin:thioredoxin reductase complexferritin complex +FHF complexfibrinogen complexfibronectin-tissue transglutaminase complexfilamentous actinflotillin complexfollicle-stimulating hormone complexformate dehydrogenase complexformyl-methanofuran dehydrogenase (molybdenum enzyme) complexformyl-methanofuran dehydrogenase (tungsten enzyme) complexfumarate reductase complex +G-protein alpha(13)-synembrin complexG-protein alpha(i)1-synembrin complexG-protein alpha(o)-synembrin complexG-protein alpha(q)-synembrin complexG-protein beta/gamma-Btk complexG-protein beta/gamma-Raf-1 complexG-protein beta/gamma-subunit complexGAIT complexgamma-secretase complexgamma-secretase-Delta1 complexgamma-tubulin complex +GARP complexGATA1-TAL1-TCF3-Lmo2 complexGATA2-TAL1-TCF3-Lmo2 complexGCH1 complexGemin3-Gemin4-Gemin5 complexGemin6-Gemin7-unrip complexGET complexGID complexglucose-1-phosphate adenylyltransferase complexglucosidase II complexglutamate synthase complex +glutamate-cysteine ligase complexglutamate-tRNA ligase complexglutamyl-tRNA(Gln) amidotransferase complexglutathione synthase complexglycerol-3-phosphate dehydrogenase complexglycine cleavage complexglycine reductase complexglycine-tRNA ligase complexglycolate oxidase complexglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complexGolgi transport complexGPI-anchor transamidase complexGrb2-EGFR complexGrb2-Shc complexGrb2-SHP-2 complexGrb2-Sos complexguanyl-nucleotide exchange factor complexguanylate cyclase complex, solublehaptoglobin-hemoglobin complexHedgehog signaling complexhemoglobin complexheterotrimeric G-protein complexHICS complexhigh affinity iron permease complexHIR complexhistone acetyltransferase complex +histone deacetylase complex +Holliday junction resolvase complex +HOPS complexHslUV protease complexhydrogen:potassium-exchanging ATPase complexi-AAA complexI-kappaB/NF-kappaB complex +Ig heavy chain-bound endoplasmic reticulum chaperone complexIkappaB kinase complexIKKalpha-IKKalpha compleximidazoleglycerol-phosphate synthase compleximmunoglobulin complex +inaD signaling complexinhibin complex +inhibin-betaglycan-ActRII complexinositol phosphoceramide synthase complexinsulin-like growth factor binding protein complex +integrator complexinterferon regulatory factor complex +interleukin-12 complexinterleukin-12-interleukin-12 receptor complexinterleukin-23 complexinterleukin-27 complexinterleukin-35 complexinterleukin4-interleukin-4 receptor complexintermediate filament +intraflagellar transport particle +intraflagellar transport particle Aintraflagellar transport particle Bion channel complex +IPAF inflammasome complexisoamylase complex +junctional membrane complexKibra-Ex-Mer complexkinetochore +Ku70:Ku80 complexlaminin complex +large latent transforming growth factor-beta complexlarval serum protein complexLid2 complexlight-harvesting complex +Lsd1/2 complexluminal surveillance complexlysosomal multienzyme complexm-AAA complexmagnesium chelatase complexMAML1-RBP-Jkappa- ICN1 complexMAML2-RBP-Jkappa-ICN1 complexMAML2-RBP-Jkappa-ICN2 complexMAML2-RBP-Jkappa-ICN3 complexMAML2-RBP-Jkappa-ICN4 complexMAML3-RBP-Jkappa-ICN1 complexMAML3-RBP-Jkappa-ICN2 complexMAML3-RBP-Jkappa-ICN3 complexMAML3-RBP-Jkappa-ICN4 complexmannosyltransferase complex +MCM complex +MCM core complexMECO complexmedial cortical nodemediator complexmeiotic recombination initiation complexmembrane coat +meprin A complexmethane monooxygenase complexmethanophenazine reducing hydrogenase complexmethionine adenosyltransferase complexmethionyl glutamyl tRNA synthetase complexmethyl coenzyme M reductase complexmethyl-tetrahydromethanopterin:coenzyme M methyltransferase complexmethylthiol:coenzyme M methyltransferase complexmethyltransferase complex +MHC class I peptide loading complex +MHC protein complex +microprocessor complexmicrotubule +microtubule associated complex +MIS12/MIND type complex +Mis6-Sim4 complexmismatch repair complex +mitochondrial inner membrane peptidase complexmitochondrial inner membrane presequence translocase complex +mitochondrial inner membrane protein insertion complexmitochondrial intermembrane space protein transporter complexmitochondrial outer membrane translocase complexmitochondrial processing peptidase complexmitochondrial prohibitin complexmitochondrial respiratory chain complex I, membrane segmentmitochondrial respiratory chain complex I, peripheral segmentmitochondrial respiratory chain supercomplexmitochondrial sorting and assembly machinery complexmitotic checkpoint complexMMXD complexmolybdopterin synthase complexMon1-Ccz1 complexmonopolin complexMpp10 complexMPP7-DLG1-LIN7 complexMre11 complexmRNA cleavage factor complex +mRNA editing complex +mTOR-FKBP12-rapamycin complexMyb complexMyo2p-Vac17p-Vac8p transport complexmyosin complex +NAD(P)+ transhydrogenase complex (AB-specific)NAD(P)H dehydrogenase complex (plastoquinone)NADH dehydrogenase complex +NADPH oxidase complexnascent polypeptide-associated complexNdc80 complexnexin complexNF-kappaB complex +NHE3/E3KARP/ACTN4 complexnitrate reductase complexnitrite reductase complex [NAD(P)H]nitrogenase complex +NLRP1 inflammasome complexNLRP3 inflammasome complexNMS complexNoc complex +nonhomologous end joining complex +NOS2-CD74 complexNrd1 complexnuclear pore central transport channelnuclear pore cytoplasmic filamentsnuclear pore inner ringnuclear pore linkersnuclear pore nuclear basketnuclear pore outer ringnuclear pore transmembrane ringnuclear RNA export factor complexnucleocytoplasmic shuttling complex +nucleolus organizer regionnucleotide-excision repair complex +oligosaccharyltransferase complex +origin recognition complex +ornithine carbamoyltransferase complexOst-alpha/Ost-beta complexoxoglutarate dehydrogenase complex +oxygen evolving complexP-TEFb-cap methyltransferase complexpalmitoyltransferase complex +PAN complexPar3-APC-KIF3A complexparaferritin complexPAS complexPcG protein complex +PCNA complexPCNA-p21 complexPDX1-PBX1b-MRG1 complexPeBoW complexphenylalanine-tRNA ligase complexphosphatidylinositol 3-kinase complex +phosphoenolpyruvate-dependent sugar phosphotransferase complexphosphopantothenoylcysteine decarboxylase complexphosphopyruvate hydratase complexphosphoribosylaminoimidazole carboxylase complexphosphorylase kinase complexphotosystem +photosystem I antenna complexphotosystem I reaction centerphotosystem II antenna complexphotosystem II reaction centerpICln-Sm protein complexpodosomepolarisome +polkadotspolycystin complexpolyketide synthase complex +polyphosphate kinase complexpore complex +pre-B cell receptor complexprefoldin complexpresequence translocase-associated import motorprocollagen-proline 4-dioxygenase complex +protease inhibitor complex +proteasome accessory complex +proteasome activator complexproteasome complex +proteasome core complex +proteasome core complex, alpha-subunit complex +proteasome core complex, beta-subunit complex +proteasome regulatory particle +proteasome regulatory particle, base subcomplex +proteasome regulatory particle, lid subcomplex +proteasome-activating nucleotidase complexprotein acetyltransferase complex +protein farnesyltransferase complexprotein histidine kinase complexprotein kinase CK2 complexprotein N-acetylglucosaminyltransferase complexprotein serine/threonine phosphatase complex +protein-N(PI)-phosphohistidine-sugar phosphotransferase complexprotocadherin-alpha-protocadherin-gamma complex +proton-transporting ATP synthase, catalytic core +proton-transporting ATP synthase, central stalk +proton-transporting ATP synthase, stator stalk +proton-transporting two-sector ATPase complex +proton-transporting two-sector ATPase complex, catalytic domain +proton-transporting two-sector ATPase complex, proton-transporting domain +Prp19 complexPSII associated light-harvesting complex II, core complexPSII associated light-harvesting complex II, peripheral complex +PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplexPwp2p-containing subcomplex of 90S preribosomepyrophosphate-dependent phosphofructokinase complex +pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complexpyrophosphate-dependent phosphofructokinase complex, beta-subunit complexpyruvate dehydrogenase (lipoamide) phosphatase complex +pyruvate dehydrogenase complex +R2TP complexRab-protein geranylgeranyltransferase complexRad17 RFC-like complexradial spoke +radial spoke stalkradial spokeheadRagulator complexRasGAP-Fyn-Lyn-Yes complexRAVE complexRC-1 DNA recombination complexRCAF complexreceptor complex +RecFOR complexRecQ helicase-Topo III complexreplication fork protection complexreplication inhibiting complex +RES complexrespiratory chain complex II +respiratory chain complex III +respiratory chain complex IV +retromer complex +retromer complex, inner shellretromer complex, outer shellRGS6-DNMT1-DMAP1 complexriboflavin synthase complexribonuclease H2 complexribonucleoside-diphosphate reductase complexribose phosphate diphosphokinase complexribulose bisphosphate carboxylase complex +Ric1p-Rgp1p complexripoptosomeRix1 complexRNA cap binding complex +RNA polymerase complex +RPAP3/R2TP/prefoldin-like complexsarcoglycan complexsarcosine oxidase complexSC5b-7 complexSCAR complexScrib-APC complexScrib-APC-beta-catenin complexSec62/Sec63 complexSeh1-associated complexseptin complex +serine-pyruvate aminotransferase complexShc-EGFR complexShc-Grb2-Sos complexShu complexSid2-Mob1 complexsignal peptidase complexsignal recognition particle receptor complexsignalosomesingle-stranded DNA-binding protein complexSki complexSlx1-Slx4 complexSMAD protein complex +SMC loading complexSmc5-Smc6 complexSMN complexSMN-Gemin2 complexSMN-Sm protein complex +SNARE complex +SOD1-Bcl-2 complexSOD1-calcineurin complexsodium ion-transporting two-sector ATPase complex +sodium:potassium-exchanging ATPase complexSOSS complexspindle +spindle midzone +spindle pole +spindle pole body +spitzenkorperSREBP-SCAP complexSREBP-SCAP-Insig complexSSL2-core TFIIH complex +starch utilization system complexstereocilia ankle link complexsteroid hormone aporeceptor complexsuccinate dehydrogenase complex +sucrase-isomaltase complexsulfate adenylyltransferase complex (ATP)sulfite reductase complex (NADPH)sulfopyruvate decarboxylase complexSUMO activating enzyme complexSUN-KASH complexSWI/SNF superfamily-type complex +Swi5-Swi2 complexsyntrophin complext-UTP complexTACC/TOG complexTAM protein secretion complexTAP complexTAT protein transport complexTCTN-B9D complexTEAD-2 multiprotein complexthioglucosidase complexTHO complex +Tic complexToc complexTor2-Mei2-Ste11 complexTORC1 complexTORC2 complexTRAF2-GSTP1 complexTRAMP complextranscription elongation factor complex +transcription export complex +transcription export complex 2transcription factor complex +transcriptional repressor complex +transforming growth factor beta activated kinase 1 complextransforming growth factor beta1-type II receptor complextransforming growth factor beta1-type II receptor-type I receptor complextranslation release factor complextranslocon complex +TRAPP complex +tricarboxylic acid cycle enzyme complex +trimethylamine-N-oxide reductase complextripartite ATP-independent periplasmic transporter complextRNA-intron endonuclease complextRNA-specific adenosine-34 deaminase complextRNA-splicing ligase complextroponin complexTSC1-TSC2 complextubulin complextubulobulbar complextype I protein secretion system complexType I site-specific deoxyribonuclease complextype II protein secretion system complexType II site-specific deoxyribonuclease complextype III protein secretion system complexType III site-specific deoxyribonuclease complextype IV secretion system complexType IV site-specific deoxyribonuclease complextype V protein secretion system complextype VI protein secretion system complexubiquitin conjugating enzyme complex +ubiquitin ligase complex +UDP-N-acetylglucosamine transferase complexUDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexULK1-ATG13-FIP200 complexurease complexUTP-C complexvacuolar transporter chaperone complexviral integration complexviral portal complexviral scaffoldviral terminase complex +viral transcriptional complexvirus terminase, large subunitVps55/Vps68 complexVRK3/VHR/ERK complexWASH complexxanthine dehydrogenase complexzona pellucida receptor complexcellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentorganelleintracellular organelleintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellecytoskeletonactin cytoskeletonactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actomyosin +actomyosin contractile ring +Arp2/3 protein complexcortical actin cytoskeleton +dynactin complex +F-actin capping protein complex +myosin complex +podosomestriated muscle thin filament +cellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellecytoskeletoncytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentorganelleorganelle partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexcellular_componentorganelle partintracellular organelle partcytoskeletal partactin capactin cortical patchactin filament [GO:0005884] (64 genes, 69 annotations)actomyosin, actin partcontractile vacuole porefilamentous actinactin filament bundle +actin rod +actin tubuleactomyosin +actomyosin contractile ring +Arp2/3 protein complexaster +centralspindlin complexciliary rootletcleavage apparatus septin structure +conoidcontractile vacuole porecortical actin cytoskeleton +cortical microtubule cytoskeleton +cuticular platecytoskeletal calyxdeep fiberF-actin capping protein complex +filamentous actinintermediate filament +investment conemacropinocytic cup cytoskeletonmanchettemicrotubule +microtubule associated complex +microtubule bundle +microtubule organizing center +microtubule organizing center part +microtubule plus endMMXD complexmuscle thin filament tropomyosinmyosin complex +podosomepostsynaptic densitypreprophase bandseptin band +septin cap +septin collar +septin complex +septin filament array +septin ring +spectrinspindle +spindle matrixspindle midzone +spindle pole +split septin rings +striated muscle thin filament +subpellicular networktroponin complextubulin complexMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 06/05/2013 MGI 5.13 |
|
|
|
||
Analysis Tools