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Gene Ontology Browser
Term Detail
GO term:AP-3 adaptor complex
GO id:GO:0030123
Definition:A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
Number of paths to term: 23

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasm
                                                        part-ofcytoplasmic part
                                                                is-aAP-type membrane coat adaptor complex
                                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                        is-aAP-4 adaptor complex
                                                                        is-aAP-5 adaptor complex
                                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasm
                                                        part-ofcytoplasmic part
                                                                is-amembrane coat
                                                                        part-ofAP-type membrane coat adaptor complex
                                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                                is-aAP-4 adaptor complex
                                                                                is-aAP-5 adaptor complex
                                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasmic part
                                                        is-aAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasmic part
                                                        is-amembrane coat
                                                                part-ofAP-type membrane coat adaptor complex
                                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                        is-aAP-4 adaptor complex
                                                                        is-aAP-5 adaptor complex
                                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-amembrane coat
                                                                part-ofAP-type membrane coat adaptor complex
                                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                        is-aAP-4 adaptor complex
                                                                        is-aAP-5 adaptor complex
                                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasmic part
                                                is-aAP-type membrane coat adaptor complex
                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                        is-aAP-4 adaptor complex
                                                        is-aAP-5 adaptor complex
                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasmic part
                                                is-amembrane coat
                                                        part-ofAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-amembrane coat
                                                                part-ofAP-type membrane coat adaptor complex
                                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                        is-aAP-4 adaptor complex
                                                                        is-aAP-5 adaptor complex
                                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasmic part
                                                is-aAP-type membrane coat adaptor complex
                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                        is-aAP-4 adaptor complex
                                                        is-aAP-5 adaptor complex
                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasmic part
                                                is-amembrane coat
                                                        part-ofAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasm
                                        part-ofcytoplasmic part
                                                is-aAP-type membrane coat adaptor complex
                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                        is-aAP-4 adaptor complex
                                                        is-aAP-5 adaptor complex
                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasm
                                        part-ofcytoplasmic part
                                                is-amembrane coat
                                                        part-ofAP-type membrane coat adaptor complex
                                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                                is-aAP-4 adaptor complex
                                                                is-aAP-5 adaptor complex
                                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasmic part
                                        is-aAP-type membrane coat adaptor complex
                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                is-aAP-4 adaptor complex
                                                is-aAP-5 adaptor complex
                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasmic part
                                        is-amembrane coat
                                                part-ofAP-type membrane coat adaptor complex
                                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                        is-aAP-4 adaptor complex
                                                        is-aAP-5 adaptor complex
                                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aprotein complex
                                is-aAP-type membrane coat adaptor complex
                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                        is-aAP-4 adaptor complex
                                        is-aAP-5 adaptor complex
                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aprotein complex
                                is-amembrane coat
                                        part-ofAP-type membrane coat adaptor complex
                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                is-aAP-4 adaptor complex
                                                is-aAP-5 adaptor complex
                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amembrane
                        is-acoated membrane
                                part-ofmembrane coat
                                        part-ofAP-type membrane coat adaptor complex
                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                is-aAP-4 adaptor complex
                                                is-aAP-5 adaptor complex
                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aAP-type membrane coat adaptor complex
                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                        is-aAP-4 adaptor complex
                                        is-aAP-5 adaptor complex
                                        is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-amembrane coat
                                        part-ofAP-type membrane coat adaptor complex
                                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                                is-aAP-4 adaptor complex
                                                is-aAP-5 adaptor complex
                                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aAP-type membrane coat adaptor complex
                                is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                is-aAP-4 adaptor complex
                                is-aAP-5 adaptor complex
                                is-aclathrin adaptor complex +


Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-amembrane coat
                                part-ofAP-type membrane coat adaptor complex
                                        is-aAP-3 adaptor complex [GO:0030123] (4 genes, 4 annotations)
                                        is-aAP-4 adaptor complex
                                        is-aAP-5 adaptor complex
                                        is-aclathrin adaptor complex +


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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory