Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Syp

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SYP
- Mouse genes Syp
- Rat genes Syp
- Zfish genes sypa,sypb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	SYP	IDA		Human	PMID:10620806
Molecular Function	GO:0042802	identical protein binding	Syp	IPI	PR:Q62277	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:A0A384ME17	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O60225-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O75127	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O75155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O95363	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:O95971	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P30405	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P39905-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P43378	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q13596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q6IN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q8N0V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q8TAC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96AL5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96C03-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96DR4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96E11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96E29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96P53	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9C0E8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9H0W8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9HB07	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9NQG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9NR28	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9UBD0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9UKF7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9ULP0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9Y371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9Y4P8-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q13885	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SYP	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:O70166	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:Q8K021	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:Q8R191	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:Q8BG07	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:P63044	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:Q9QYM5	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	PR:Q8K221	Mouse	PMID:18706977
Molecular Function	GO:0005515	protein binding	Syp	IPI	RGD:620449	Rat	PMID:11786535\|RGD:633984
Molecular Function	GO:0005515	protein binding	Syp	IPI	UniProtKB:P33535	Rat	PMID:17005904\|RGD:8554727
Molecular Function	GO:0005515	protein binding	Syp	IPI	UniProtKB:Q9QWI6-2	Rat	PMID:18662323\|RGD:8553600
Molecular Function	GO:0005515	protein binding	Syp	IPI	UniProtKB:Q5XIE8	Rat	PMID:29476059\|RGD:42721991
Molecular Function	GO:0019904	protein domain specific binding	Syp	IPI	RGD:620778	Rat	PMID:11786535\|RGD:633984
Molecular Function	GO:0044877	protein-containing complex binding	Syp	IPI	RGD:3949\|RGD:1306159	Rat	PMID:8567678\|RGD:2301258
Molecular Function	GO:0042169	SH2 domain binding	Syp	IDA		Mouse	PMID:18706977
Molecular Function	GO:0000149	SNARE binding	Syp	IPI	UniProtKB:P63044	Rat	PMID:19196426\|RGD:13702278
Molecular Function	GO:0017075	syntaxin-1 binding	Syp	IDA		Rat	PMID:7553862\|RGD:70701
Cellular Component	GO:0060076	excitatory synapse	Syp	IDA		Mouse	PMID:16980967
Cellular Component	GO:0060076	excitatory synapse	Syp	IDA		Rat	PMID:19730411\|RGD:8554379
Cellular Component	GO:0043229	intracellular organelle	Syp	IDA		Rat	PMID:10340764\|RGD:4892571
Cellular Component	GO:0016020	membrane	Syp	IDA		Mouse	PMID:15748150
Cellular Component	GO:0016020	membrane	Syp	IDA		Mouse	PMID:18706977
Cellular Component	GO:0031594	neuromuscular junction	Syp	IDA		Mouse	PMID:20826656
Cellular Component	GO:0043005	neuron projection	SYP	IDA		Human	PMID:8838578
Cellular Component	GO:0043005	neuron projection	Syp	IMP		Mouse	MGI:MGI:5286805\|PMID:21664258
Cellular Component	GO:0043005	neuron projection	Syp	IDA		Mouse	MGI:MGI:4941068\|PMID:21307259
Cellular Component	GO:0043005	neuron projection	Syp	IDA		Rat	PMID:8567678\|RGD:2301258
Cellular Component	GO:0044306	neuron projection terminus	Syp	IDA		Mouse	PMID:12074840
Cellular Component	GO:0044306	neuron projection terminus	Syp	IDA		Mouse	PMID:12115694
Cellular Component	GO:0044306	neuron projection terminus	Syp	IDA		Rat	PMID:11786535\|RGD:633984
Cellular Component	GO:0044309	neuron spine	Syp	IDA		Rat	PMID:20083202\|RGD:4107359
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Syp	IDA		Mouse	PMID:17046993
Cellular Component	GO:0014069	postsynaptic density	Syp	IDA		Rat	PMID:26595655\|RGD:11085699
Cellular Component	GO:0098793	presynapse	Syp	IDA		Mouse	PMID:31787876
Cellular Component	GO:0048786	presynaptic active zone	Syp	IDA		Mouse	MGI:MGI:5286805\|PMID:21664258
Cellular Component	GO:0048786	presynaptic active zone	Syp	IDA		Rat	PMID:17310244\|RGD:10047256
Cellular Component	GO:0042734	presynaptic membrane	Syp	IDA		Mouse	MGI:MGI:4367324\|PMID:19506089
Cellular Component	GO:0042734	presynaptic membrane	Syp	IDA		Mouse	PMID:15328414
Cellular Component	GO:0032991	protein-containing complex	Syp	IDA		Rat	PMID:8567678\|RGD:2301258
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syp	IMP		Mouse	PMID:10595519
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syp	IDA		Mouse	PMID:10595519
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:12533614
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:14622577
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:23986251
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:18706977
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:10712642
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:12368914
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:10995443
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:17823315
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:23704327
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:17018287
Cellular Component	GO:0045202	synapse	Syp	IDA		Mouse	PMID:18279309
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:16407767
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:21884692
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:9364068
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:17360631
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:11879655
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Mouse	PMID:12202822
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Rat	PMID:10908612\|RGD:634537
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Rat	PMID:12928441\|RGD:8554439
Cellular Component	GO:0008021	synaptic vesicle	Syp	IDA		Rat	PMID:17004320\|RGD:12050136
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Mouse	PMID:29490264
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Mouse	PMID:12805290
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Mouse	PMID:15071120
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Rat	PMID:3923488\|RGD:13702387
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Rat	PMID:17004320\|RGD:12050136
Cellular Component	GO:0030672	synaptic vesicle membrane	Syp	IDA		Rat	PMID:23792689\|RGD:12793033
Cellular Component	GO:0043195	terminal bouton	Syp	IDA		Mouse	PMID:29350434
Cellular Component	GO:0043195	terminal bouton	Syp	IDA		Mouse	PMID:20203623
Cellular Component	GO:0043195	terminal bouton	Syp	IDA		Rat	PMID:12181340\|RGD:13210561
Cellular Component	GO:0043195	terminal bouton	Syp	HDA		Rat	PMID:24876496\|RGD:10047219
Biological Process	GO:0071310	cellular response to organic substance	Syp	IDA		Mouse	PMID:18497889
Biological Process	GO:0006897	endocytosis	Syp	IMP		Rat	PMID:17005904\|RGD:8554727
Biological Process	GO:0021782	glial cell development	sypb	IMP	ZFIN:ZDB-CRISPR-191009-25,ZFIN:ZDB-CRISPR-191009-26	Zfish	PMID:30924555
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Syp	IMP		Mouse	MGI:MGI:1349221\|PMID:10595519
Biological Process	GO:2000474	regulation of opioid receptor signaling pathway	Syp	IDA		Rat	PMID:17005904\|RGD:8554727
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	Syp	IMP		Mouse	MGI:MGI:1349221\|PMID:10595519
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Syp	IMP		Mouse	PMID:10595519
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Syp	IDA		Mouse	PMID:10595519
Biological Process	GO:1904645	response to amyloid-beta	Syp	IEP		Rat	PMID:20847448\|RGD:13506238
Biological Process	GO:0060041	retina development in camera-type eye	sypb	IMP	ZFIN:ZDB-CRISPR-191009-25,ZFIN:ZDB-CRISPR-191009-26	Zfish	PMID:30924555
Biological Process	GO:0048488	synaptic vesicle endocytosis	Syp	IMP		Mouse	MGI:MGI:5141572\|PMID:21658579

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.