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Gene Ontology Browser
Term Detail
GO term:presynaptic active zone
Synonym: pre-synaptic active zone
Synonym: pre-synaptic active zone component
GO id:GO:0048786
Definition:A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aneuron part
                                        is-aapical pole of neuron
                                        is-aaxon part +
                                        is-abasal pole of neuron
                                        is-adendrite cytoplasm
                                        is-adendrite terminus +
                                        is-adendritic branch
                                        is-adendritic branch point
                                        is-adendritic filopodium
                                        is-adendritic microtubule
                                        is-adendritic shaft
                                        is-adendritic spine head
                                        is-adendritic spine neck
                                        is-adendritic tree
                                        is-agrowth cone +
                                        is-agrowth cone membrane
                                        is-aLewy body +
                                        is-aLewy body core
                                        is-aLewy body corona
                                        is-aLewy body-like hyaline inclusion
                                        is-anBAF complex
                                        is-aneurofibrillary tangle
                                        is-aneurofilament cytoskeleton
                                        is-aneuron projection +
                                        is-aneuron projection membrane +
                                        is-aneuron projection terminus +
                                        is-aneuronal cell body +
                                        is-aneuronal cell body membrane
                                        is-aneuronal postsynaptic density
                                        is-aneuronal ribonucleoprotein granule
                                        is-aperikaryon
                                        is-aphotoreceptor disc membrane
                                        is-aphotoreceptor inner segment +
                                        is-aphotoreceptor inner segment membrane
                                        is-aphotoreceptor outer segment +
                                        is-aphotoreceptor outer segment membrane
                                        is-apresynaptic active zone [GO:0048786] (17 genes, 20 annotations)
                                                part-ofpresynaptic active zone dense projection
                                                part-ofpresynaptic active zone membrane
                                                part-ofpresynaptic cytoskeletal matrix assembled at active zones
                                                part-ofpresynaptic grid
                                        is-apresynaptic active zone dense projection
                                        is-apresynaptic cytoskeletal matrix assembled at active zones
                                        is-apresynaptic grid
                                        is-apresynaptic membrane +
                                        is-asomatodendritic compartment +
                                        is-aspine apparatus
                                        is-aspine mat
                                        is-asubplasmalemmal coating


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aneuron part
                                is-aapical pole of neuron
                                is-aaxon part +
                                is-abasal pole of neuron
                                is-adendrite cytoplasm
                                is-adendrite terminus +
                                is-adendritic branch
                                is-adendritic branch point
                                is-adendritic filopodium
                                is-adendritic microtubule
                                is-adendritic shaft
                                is-adendritic spine head
                                is-adendritic spine neck
                                is-adendritic tree
                                is-agrowth cone +
                                is-agrowth cone membrane
                                is-aLewy body +
                                is-aLewy body core
                                is-aLewy body corona
                                is-aLewy body-like hyaline inclusion
                                is-anBAF complex
                                is-aneurofibrillary tangle
                                is-aneurofilament cytoskeleton
                                is-aneuron projection +
                                is-aneuron projection membrane +
                                is-aneuron projection terminus +
                                is-aneuronal cell body +
                                is-aneuronal cell body membrane
                                is-aneuronal postsynaptic density
                                is-aneuronal ribonucleoprotein granule
                                is-aperikaryon
                                is-aphotoreceptor disc membrane
                                is-aphotoreceptor inner segment +
                                is-aphotoreceptor inner segment membrane
                                is-aphotoreceptor outer segment +
                                is-aphotoreceptor outer segment membrane
                                is-apresynaptic active zone [GO:0048786] (17 genes, 20 annotations)
                                        part-ofpresynaptic active zone dense projection
                                        part-ofpresynaptic active zone membrane
                                        part-ofpresynaptic cytoskeletal matrix assembled at active zones
                                        part-ofpresynaptic grid
                                is-apresynaptic active zone dense projection
                                is-apresynaptic cytoskeletal matrix assembled at active zones
                                is-apresynaptic grid
                                is-apresynaptic membrane +
                                is-asomatodendritic compartment +
                                is-aspine apparatus
                                is-aspine mat
                                is-asubplasmalemmal coating


Gene_Ontology
        is-acellular_component
                is-asynapse
                        part-ofsynapse part
                                is-aclathrin coat of synaptic vesicle
                                is-aintegral component of synaptic vesicle membrane
                                is-aintrinsic component of synaptic vesicle membrane +
                                is-apostsynaptic density +
                                is-apresynaptic active zone [GO:0048786] (17 genes, 20 annotations)
                                        part-ofpresynaptic active zone dense projection
                                        part-ofpresynaptic active zone membrane
                                        part-ofpresynaptic cytoskeletal matrix assembled at active zones
                                        part-ofpresynaptic grid
                                is-apresynaptic active zone dense projection
                                is-apresynaptic cytoskeletal matrix assembled at active zones
                                is-apresynaptic grid
                                is-apresynaptic periactive zone
                                is-asubsynaptic reticulum
                                is-asynaptic cleft
                                is-asynaptic membrane +
                                is-asynaptic vesicle +
                                is-asynaptic vesicle lumen
                                is-asynaptic vesicle membrane +
                                is-aterminal bouton +


Gene_Ontology
        is-acellular_component
                is-asynapse part
                        is-aclathrin coat of synaptic vesicle
                        is-aintegral component of synaptic vesicle membrane
                        is-aintrinsic component of synaptic vesicle membrane +
                        is-apostsynaptic density +
                        is-apresynaptic active zone [GO:0048786] (17 genes, 20 annotations)
                                part-ofpresynaptic active zone dense projection
                                part-ofpresynaptic active zone membrane
                                part-ofpresynaptic cytoskeletal matrix assembled at active zones
                                part-ofpresynaptic grid
                        is-apresynaptic active zone dense projection
                        is-apresynaptic cytoskeletal matrix assembled at active zones
                        is-apresynaptic grid
                        is-apresynaptic periactive zone
                        is-asubsynaptic reticulum
                        is-asynaptic cleft
                        is-asynaptic membrane +
                        is-asynaptic vesicle +
                        is-asynaptic vesicle lumen
                        is-asynaptic vesicle membrane +
                        is-aterminal bouton +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory