| GO term: | presynaptic active zone |
| Synonym: | pre-synaptic active zone |
| GO id: | GO:0048786 |
| Definition: | A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix. |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partneuron partdendritic treeLewy body +Lewy body-like hyaline inclusionnBAF complexneurofibrillary tangleneurofilament cytoskeleton +neuron projection +neuronal cell body +presynaptic active zone [GO:0048786] (16 genes, 18 annotations)presynaptic active zone dense projectionpresynaptic active zone membranepresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic membrane +spine apparatusspine matsubplasmalemmal coatingcellular_componentcell partneuron partdendritic treeLewy body +Lewy body-like hyaline inclusionnBAF complexneurofibrillary tangleneurofilament cytoskeleton +neuron projection +neuronal cell body +presynaptic active zone [GO:0048786] (16 genes, 18 annotations)presynaptic active zone dense projectionpresynaptic active zone membranepresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic membrane +spine apparatusspine matsubplasmalemmal coatingcellular_componentsynapsesynapse partclathrin coat of synaptic vesicleintegral to synaptic vesicle membranepostsynaptic densitypresynaptic active zone [GO:0048786] (16 genes, 18 annotations)presynaptic active zone dense projectionpresynaptic active zone membranepresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic active zone dense projectionpresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic periactive zonesubsynaptic reticulumsynaptic cleftsynaptic membrane +synaptic vesicle +synaptic vesicle lumensynaptic vesicle membrane +terminal bouton +cellular_componentsynapse partclathrin coat of synaptic vesicleintegral to synaptic vesicle membranepostsynaptic densitypresynaptic active zone [GO:0048786] (16 genes, 18 annotations)presynaptic active zone dense projectionpresynaptic active zone membranepresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic active zone dense projectionpresynaptic cytoskeletal matrix assembled at active zonespresynaptic gridpresynaptic periactive zonesubsynaptic reticulumsynaptic cleftsynaptic membrane +synaptic vesicle +synaptic vesicle lumensynaptic vesicle membrane +terminal bouton +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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